scholarly journals Pharmacokinetics and Pharmacodynamics of Dexmedetomidine Administered as an Adjunct to Bupivacaine for Transversus Abdominis Plane Block in Patients Undergoing Lower Abdominal Cancer Surgery

2022 ◽  
Vol Volume 15 ◽  
pp. 1-12
Author(s):  
Fatma A El Sherif ◽  
Hala Abdel-Ghaffar ◽  
Ahmed Othman ◽  
Sahar Mohamed ◽  
Mervat Omran ◽  
...  
Keyword(s):  
Transversus Abdominis Plane Block ◽  
Cancer Surgery ◽  
Transversus Abdominis ◽  
Transversus Abdominis Plane ◽  
Pharmacokinetics And Pharmacodynamics

Transversus Abdominis Plane Block Does Not Provide Additional Benefit to Multimodal Analgesia in Gynecological Cancer Surgery

2010 ◽  
Vol 111 (3) ◽  
pp. 797-801 ◽  
Author(s):  
James D. Griffiths ◽  
Justine V. Middle ◽  
Fiona A. Barron ◽  
Sarah J. Grant ◽  
Phillip A. Popham ◽  
...  
Keyword(s):  
Gynecological Cancer ◽  
Multimodal Analgesia ◽  
Transversus Abdominis Plane Block ◽  
Additional Benefit ◽  
Cancer Surgery ◽  
Transversus Abdominis ◽  
Transversus Abdominis Plane

The Analgesic Efficacy of Postoperative Bilateral, Ultrasound-Guided, Posterior Transversus Abdominis Plane Block for Laparoscopic Colorectal Cancer Surgery: A Randomized, Prospective, Controlled Study

2020 ◽  
Author(s):  
Yang Zhao ◽  
Han-Ying Zhang ◽  
Zong-Yi Yuan ◽  
Yi Han ◽  
Yi-Rong Chen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Rating Scale ◽  
Transversus Abdominis Plane Block ◽  
Cancer Surgery ◽  
Transversus Abdominis ◽  
Transversus Abdominis Plane ◽  
Ultrasound Guided ◽  
Colorectal Cancer Surgery ◽  
Pain Scores ◽  
Group Control

Abstract Background: The study aimed to observe whether a postoperative bilateral, ultrasound-guided, posterior transversus abdominis plane block offers more benefits than placebo in patients undergoing elective laparoscopic colorectal cancer surgery in the enhanced recovery after surgery program.Methods: Patients scheduled to undergo elective laparoscopic surgery following the diagnosis of colorectal cancer were included in this study and randomized into Group TAP and Group Control. The patients received a postoperative bilateral, ultrasound-guided, posterior transversus abdominis plane block either 20 mL of 0.5% ropivacaine (Group TAP) per side or an equivalent volume of normal saline (Group Control). The primary outcome was the cumulative consumption of rescue tramadol within 24 h after the surgery. Secondary endpoints included numerical rating scale (NRS) pain scores at rest and movement at 2, 4, 6, 12, 24, 36, 48, and 72 h. The related side effects, time to the first request for rescue tramadol, patient satisfaction on postoperative analgesia, time to the intestinal function return, time to mobilization, and the length of hospital stay were recorded.Results: In total, 92 patients were randomized, and 82 completed the trial. The posterior TAP block reduced numeric rating scale pain scores at rest and movement at 2, 4, 6, 12, and 24 h after surgery but showed similar scores at 48 or 72 h. The total rescue tramadol requirement within the first 24 h reduced in Group TAP. A higher level of satisfaction with postoperative analgesia was observed in Group TAP on day 1 which was similar on days 2 and 3, compared with the Group Control. There were no complications due to the TAP block. A few incidences of opioids related side effects and a lower percentage of patients needing rescue tramadol analgesia within 24 h were observed in Group TAP. The time to the first request for rescue analgesia was prolonged, and the time to mobilization and flatus was reduced with a shorter hospital stay in Group TAP.Conclusions: A postoperative bilateral, ultrasound-guided, posterior transversus abdominis plane block resulted in better pain relief and a faster recovery in patients undergoing laparoscopic colorectal cancer surgery, without adverse effects. Trial registration: The study was registered at http://www.chictr.org.cn (ChiCTR-IPR-17012650，12, Sep 2017).

EFFICACY OF TRANSVERSUS ABDOMINIS PLANE BLOCK FOR POST CESAREAN DELIVERY ANALGESIA

2018 ◽  
Vol 8 (5) ◽  
pp. 37-41
Author(s):  
Minh Nguyen Van ◽  
Nga Bui Thi Thuy ◽  
Thinh Tran Xuan
Keyword(s):  
Caesarean Section ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Transversus Abdominis Plane Block ◽  
Transversus Abdominis ◽  
Morphine Consumption ◽  
Block Group ◽  
Tap Block ◽  
Transversus Abdominis Plane ◽  
Pain Scores

Background: The transversus abdominis plane block (TAP block), a regional block, provides effective analgesia after lower abdominal surgeries. The objective of this study was to assess whether transversus abdominis plane block is effective as part of multimodal pain management following Cesarean section. Materials and Method: Totally, 60 ASA I and II parturients for Cesarean section via Pfannenstiel incision under spinal anesthesia were randomly allocated to either the TAP block group or the control. The TAP block group received a landmark-orientated, bilateral TAP block with 0.25% levobupivacain 17,5ml each side in the triangle of Petit. Postoperative pain treatment followed the same protocole for both groups with 1gram paracetamol intravenously and received patrient-controlled analgesia with intravenous morphine. The time to first request of analgesic, morphine consumption, visual analogue scale (VAS) pain scores and side effects were scored at 2, 4, 6, 8, 12 h postoperatively. Results: The time to first request of analgesic was longer, morphine consumption was lower in TAP group than in the control (p < 0.05). Visual analogue scale (VAS) pain scores at rest and on mouvement were similar in two groups at 2h, but lower in TAP group from 4h (p < 0.05). No severe adverse effects were detected in two groups. Conclusion: TAP block prolonged the time to fisrt request of analgesic and reduced morphine consumption, the VAS pain scores significantly both at rest and on mouvement. Therefore, TAP block is feasible and effective as part of a multimodal analgesia regimen after Caesarean section. Key words: Caesarean section, multimodal pain management, transversus abdominis plane block

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