scholarly journals Non-Particulate Steroids (Betamethasone Sodium Phosphate, Dexamethasone Sodium Phosphate, and Dexamethasone Palmitate) Combined with Local Anesthetics (Ropivacaine, Levobupivacaine, Bupivacaine, and Lidocaine): A Potentially Unsafe Mixture

2021 ◽  
Vol Volume 14 ◽  
pp. 1495-1504
Author(s):  
Eun Joo Choi ◽  
Dong-Hyun Kim ◽  
Woong Ki Han ◽  
Ho-Jin Lee ◽  
Imhong Kang ◽  
...  
Keyword(s):  
Local Anesthetics ◽  
Sodium Phosphate ◽  
Dexamethasone Sodium Phosphate ◽  
Dexamethasone Palmitate ◽  
Betamethasone Sodium Phosphate

A comparative study of treatment for brain edema: Magnesium sulphate versus dexamethasone sodium phosphate

2008 ◽  
Vol 15 (1) ◽  
pp. 60-65 ◽  
Author(s):  
Omer Faruk Turkoglu ◽  
Hakan Eroglu ◽  
Ozerk Okutan ◽  
M. Kagan Tun ◽  
Ebru Bodur ◽  
...  
Keyword(s):  
Comparative Study ◽  
Brain Edema ◽  
Magnesium Sulphate ◽  
Sodium Phosphate ◽  
Dexamethasone Sodium Phosphate

Dexamethasone Sodium Phosphate (Decadron) versus Saline Placebo Injections in Strabismus Surgery

1982 ◽  
Vol 19 (3) ◽  
pp. 140-143
Author(s):  
Andrew E Choy ◽  
Sidney Weiss ◽  
Chris Chow ◽  
Don Kato ◽  
Larry Cacace
Keyword(s):  
Sodium Phosphate ◽  
Strabismus Surgery ◽  
Dexamethasone Sodium Phosphate

Comparison of the Particle Sizes of Different Steroids and the Effect of Dilution

2007 ◽  
Vol 106 (2) ◽  
pp. 331-338 ◽  
Author(s):  
Honorio T. Benzon ◽  
Teng-Leong Chew ◽  
Robert J. McCarthy ◽  
Hubert A. Benzon ◽  
David R. Walega
Keyword(s):  
Sodium Phosphate ◽  
Laser Scanning ◽  
Pure Liquid ◽  
Particle Sizes ◽  
Bonferroni Correction ◽  
Chi Square ◽  
Laser Scanning Confocal Microscope ◽  
Epidural Steroid Injections ◽  
Epidural Steroid ◽  
Betamethasone Sodium Phosphate

Background Central nervous system injuries after transforaminal epidural steroid injections have been ascribed to occlusion of the blood vessels supplying the spinal cord and brain by the particulate steroid. Methods The authors compared the sizes of the particles of the steroids methylprednisolone acetate, triamcinolone acetonide, dexamethasone sodium phosphate, betamethasone sodium phosphate/betamethasone acetate (both Celestone Soluspan; Schering-Plough, Kenilworth, NJ, the commercial betamethasone; and betamethasone repository, a betamethasone preparation that can be ordered from a compounding company), and betamethasone sodium phosphate. Both undiluted and diluted samples were examined. The samples were examined with a laser scanning confocal microscope, and images were analyzed and measured. The particles were categorized (or tabulated) into groups: 0-20, 21-50, 51-1000, and greater than 1000 mu. Chi-square analyses, with Bonferroni correction, were used to compare the proportion of particles among the undiluted and diluted drug formulations. Results Dexamethasone and betamethasone sodium phosphate were pure liquid. The proportion of larger particles was significantly greater in the methylprednisolone and the compounded betamethasone preparations compared with the commercial betamethasone. There was no statistical difference between the commercial betamethasone and triamcinolone, although betamethasone had a smaller percentage of the larger particles. Increased dilution of the compounded betamethasone with lidocaine decreased the percentage of the larger particles, whereas increased dilution of methylprednisolone 80 mg/ml with saline increased the proportion of larger particles. Conclusion Commercial betamethasone is the recommended preparation if a nonsoluble steroid is preferred. Dexamethasone is a nonparticulate steroid, but its routine use awaits further studies on its safety and efficacy.

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