scholarly journals Central Sensitization in Chronic Low Back Pain: A Population-Based Study of a Japanese Mountain Village

2021 ◽  
Vol Volume 14 ◽  
pp. 1271-1280
Author(s):  
Koji Akeda ◽  
Norihiko Takegami ◽  
Junichi Yamada ◽  
Tatsuhiko Fujiwara ◽  
Akinobu Nishimura ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Central Sensitization ◽  
Population Based ◽  
Low Back ◽  
Population Based Study ◽  
Mountain Village

scholarly journals The genetic influence of the brain-derived neurotrophic factor Val66Met polymorphism in chronic low back pain

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Angela Shiratsu Yamada ◽  
Flavia Tasmim Techera Antunes ◽  
Camila Ferraz ◽  
Alessandra Hubner de Souza ◽  
Daniel Simon
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Neurotrophic Factor ◽  
Central Sensitization ◽  
Low Back ◽  
Bdnf Gene ◽  
Val66met Polymorphism ◽  
Bdnf Val66met Polymorphism ◽  
The Brain

Abstract Background The Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene is a potential biomarker of vulnerability to pain. Thus, the present study aimed to investigate the association of this polymorphism with clinical and biopsychosocial factors in patients with chronic low back pain (CLBP). Methods A total of 107 individuals with CLBP answered questionnaires that were validated and adapted for the Brazilian population, including the Brief Inventory of Pain, the Central Sensitization Inventory, the Roland Morris Disability Questionnaire, the Tampa Scale for Kinesiophobia, the Pain Catastrophizing Scale, the Survey of Pain Attitude-Brief, and the Hospital Anxiety and Depression Scale. All of the subjects were genotyped for the BDNF Val66Met polymorphism. Results The sample showed moderate scores of disability, central sensitization, and kinesiophobia, in addition to mild anxiety, hopelessness, and ruminant thoughts. No significant association was observed between the Val66Met polymorphism and the variables analyzed. Besides, there was no relationship between the BDNF Val66Met polymorphism with CSI, catastrophization, or disabilities that were generated by CLBP. Conclusion The results showed that the Val66Met polymorphism of the BDNF gene was not associated with clinical and biopsychosocial characteristics of CLBP in the sample studied.

Motion palpation findings and self-reported low back pain in a population-based study sample

2002 ◽  
Vol 25 (2) ◽  
pp. 80-87 ◽  
Author(s):  
Charlotte Leboeuf-Yde ◽  
Jakob van Dijk ◽  
Claudia Franz ◽  
Stig Arthur Hustad ◽  
Dorthe Olsen ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Population Based ◽  
Low Back ◽  
Population Based Study

Does educational attainment increase the risk of low back pain when genetics are considered? A population-based study of Spanish twins

2017 ◽  
Vol 17 (4) ◽  
pp. 518-530 ◽  
Author(s):  
Joshua R. Zadro ◽  
Debra Shirley ◽  
Marina B. Pinheiro ◽  
Juan F. Sánchez-Romera ◽  
Francisco Pérez-Riquelme ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Educational Attainment ◽  
Population Based ◽  
Low Back ◽  
Population Based Study

Central Sensitization and Altered Central Pain Processing in Chronic Low Back Pain

2013 ◽  
Vol 29 (7) ◽  
pp. 625-638 ◽  
Author(s):  
Nathalie A. Roussel ◽  
Jo Nijs ◽  
Mira Meeus ◽  
Veit Mylius ◽  
Cécile Fayt ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Central Sensitization ◽  
Pain Processing ◽  
Central Pain ◽  
Low Back ◽  
Central Pain Processing
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