scholarly journals Sex and Gender are Not the Same: Why Identity Is Important for People Living with HIV and Chronic Pain

2020 ◽  
Vol Volume 13 ◽  
pp. 829-835
Author(s):  
Larissa J Strath ◽  
Robert E Sorge ◽  
Michael A Owens ◽  
Cesar E Gonzalez ◽  
Jennifer I Okunbor ◽  
...  
Author(s):  
Sameena Azhar ◽  
Jason Vaudrey ◽  
Sabitha Gandham ◽  
Sean Burr ◽  
Ganesh Oruganti ◽  
...  

AIDS Care ◽  
2021 ◽  
pp. 1-9
Author(s):  
Lisa R. LaRowe ◽  
John D. Cleveland ◽  
Dustin M. Long ◽  
Shadi Nahvi ◽  
Edward R. Cachay ◽  
...  

2019 ◽  
Vol 30 (5) ◽  
pp. 479-485
Author(s):  
James Muchira ◽  
Eileen Stuart-Shor ◽  
Jen Manne-Goehler ◽  
Janet Lo ◽  
Alexander C Tsai ◽  
...  

Sub-Saharan Africa (SSA) is facing a growing co-epidemic of chronic HIV infection and diabetes. Hemoglobin A1c (A1c) may underestimate glycemia among people living with HIV (PLWH). We estimated the validity of A1c to diagnose diabetes among PLWH and HIV-uninfected persons in rural Uganda. Data were derived from a cohort of PLWH and age- and gender-matched HIV-uninfected comparators. We compared A1c to fasting blood glucose (FBG) using Pearson correlations, regression models, and estimated the sensitivity and specificity of A1c for detecting diabetes with FBG ≥126 mg/dL as reference standard. Approximately half (48%) of the 212 participants were female, mean age of 51.7 years (SD = 7.0) at enrollment. All PLWH (n = 118) were on antiretroviral therapy for a median of 7.5 years with mean CD4 cell count of 442 cells/µL. Mean FBG (89.7 mg/dL) and A1c (5.6%) were not different between PLWH and HIV-uninfected ( P > 0.50) groups, but the HIV-uninfected group had a higher prevalence of A1c >5.7% (33% vs. 20%, P = 0.024). We found a relatively strong correlation between A1c and FBG (r = 0.67). An A1c ≥6.5% had a poor sensitivity (46%, 95% CI 26–67%) but high specificity (98%, 95% CI 96–99%) for detecting diabetes. More work is needed to define an optimal A1c for screening diabetes in SSA.


PAIN Reports ◽  
2019 ◽  
Vol 4 (2) ◽  
pp. e710 ◽  
Author(s):  
Terence M. Penn ◽  
Zina Trost ◽  
Romy Parker ◽  
William P. Wagner ◽  
Michael A. Owens ◽  
...  

2019 ◽  
Vol 10 ◽  
Author(s):  
Cesar E. Gonzalez ◽  
Jennifer I. Okunbor ◽  
Romy Parker ◽  
Michael A. Owens ◽  
Dyan M. White ◽  
...  

Author(s):  
Antonia L. Wadley ◽  
Tamar Pincus ◽  
Michael Evangeli

Background: Stigma related to the human immunodeficiency virus (HIV) remains common and has been associated with severity of HIV-related symptoms. Associations between HIV stigma and HIV-related pain, one of the most common symptoms in HIV, have however not been investigated. Data from low back pain populations suggest that stigma is associated with worse pain intensity and so we hypothesised that the same would be the case in HIV.Aim: The goal of this study was to assess the association between HIV stigma and pain intensity in people living with HIV (PLWH) with chronic pain whilst controlling for depression, a well-established correlate of pain.Setting: The study took place at an HIV clinic in Johannesburg, South Africa.Methods: Mediation analysis was used to assess the effect of depression on the relationship between stigma and pain intensity in a cross-sectional cohort of 50 PLWH and chronic pain (pain most days of the week for > 3 months). All participants were assessed using the HIV/AIDS Stigma Instrument – PLWA, an 11-point numerical pain rating scale and the Beck Depression Inventory II.Results: In all, 88% (44/50) of participants reported experiencing some form of HIV stigma (HIV stigma scale score ≥ 1). Worst pain intensity and depressive symptoms individually correlated with total stigma score (Spearman’s r = 0.33, p = 0.02 for both). The mediation analysis highlighted that mediation of the relationship by depression was equivocal (b = -0.002, bootstrapped confidence interval -0.02 to 0.00).Conclusion: Whilst these preliminary data are marginal, they do suggest that associations between HIV stigma and HIV-related pain warrant further investigation. Future study should also include potential mechanisms, which may include mediation through depression.


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