scholarly journals Healthcare Costs And Resource Utilization In Chronic Pain Patients Treated With Extended-Release Formulations Of Tapentadol, Oxycodone, Or Morphine Stratified By Type Of Pain: A Retrospective Claims Analysis, 2012–2016

2019 ◽  
Vol Volume 12 ◽  
pp. 3037-3048
Author(s):  
Vladimir Zah ◽  
Rowe B Brookfield ◽  
Martina Imro ◽  
Simona Tatovic ◽  
Jovana Pelivanovic ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Resource Utilization ◽  
Healthcare Costs ◽  
Extended Release ◽  
Claims Analysis ◽  
Chronic Pain Patients ◽  
Pain Patients ◽  
Extended Release Formulations

Concomitant use of benzodiazepines in chronic pain patients adherent to extended-release tapentadol or oxycodone treatment—A retrospective claims analysis

2020 ◽  
Vol 16 (6) ◽  
pp. 461-479
Author(s):  
Vladimir Zah, PhD ◽  
Martina Imro, MSc ◽  
Simona Tatovic, MSc ◽  
Michael DeGeorge, PharmD ◽  
Steven D. Passik, PhD ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Extended Release ◽  
Day Treatment ◽  
Opioid Overdose ◽  
Overdose Death ◽  
Opioid Treatment ◽  
National Mortality ◽  
Chronic Pain Patients ◽  
The Us ◽  
Pain Patients

Objective: To compare concomitant benzodiazepine (BZDs) use among chronic pain patients adherent to extended-release tapentadol (TapER) or oxycodone (OxnER) and estimate the number of lives potentially saved by switching patients to the less BZD coprescribed treatment.Design: Retrospective database study.Setting: Patients were identified using the IBM MarketScan® Commercial Database. The opioid overdose death estimates were obtained from the US national mortality register and were used to estimate the number of lives potentially saved by switching patients to the opioid treatment with lower rates of BZD coprescribing.Patients, Participants: The authors identified 30,213 chronic pain patients between October 2012 and March 2016. After propensity score matching, N = 2,355 and N = 6,761 patients were adherent (proportion of days covered ≥80 percent) to TapER and OxnER, respectively.Interventions: TapER versus OxnER, during the 180-day treatment. Main Outcome Measure(s): Proportions of BZD coprescribing, BZD dosing patterns in matched patients, and the estimated number of lives potentially saved by the opioid treatment switch.Results: TapER patients were less coprescribed BZDs during the treatment period (38.9 percent versus 49.2 percent, OR = 0.659, p 0.001), and had fewer days of BZD supply per patient (mean: 49.6 versus 70.2 days, p 0.001) with similar BZD average daily dose. Due to less frequent coprescribing of BZDs with TapER, it is estimated that ~800 deaths may have been avoided in the U.S. as a result of switching patients from OxnER to TapER.Conclusions: Among treatment-adherent patients, TapER patients had fewer BZD coprescriptions than OxnER patients had. Moreover, when BZDs were coprescribed, those BZD prescriptions were for shorter periods of time. Prospective studies are warranted to explore rates and consequences of BZD coprescribing among opioids.

scholarly journals PROJECTING THE COST, UTILIZATION, AND PATIENT CARE IMPACT OF PRESCRIBING EXTENDED RELEASE NON- ABUSE-DETERRENT OPIOIDS TO CHRONIC PAIN PATIENTS

2016 ◽  
Vol 19 (3) ◽  
pp. A247
Author(s):  
A.G. White ◽  
M. Yenikomshian ◽  
M.E. Carson ◽  
L.P. Garrison ◽  
G. Oderda ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Patient Care ◽  
Extended Release ◽  
Chronic Pain Patients ◽  
Cost Utilization ◽  
The Cost ◽  
Pain Patients

scholarly journals Postmarketing studies program to assess the risks and benefits of long-term use of extended-release/long-acting opioids among chronic pain patients

2019 ◽  
Vol 132 (1) ◽  
pp. 44-51 ◽  
Author(s):  
Paul M. Coplan ◽  
M. Soledad Cepeda ◽  
Kenneth R. Petronis ◽  
Angela DeVeaugh-Geiss ◽  
Alexandra I. Barsdorf ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Extended Release ◽  
Risks And Benefits ◽  
Chronic Pain Patients ◽  
Long Acting ◽  
Pain Patients

Tapentadol Extended Release for Chronic Pain Patients

2013 ◽  
Vol 30 (1) ◽  
pp. 14-27 ◽  
Author(s):  
Robert Taylor ◽  
Joseph V. Pergolizzi ◽  
Robert B. Raffa
Keyword(s):  
Chronic Pain ◽  
Extended Release ◽  
Chronic Pain Patients ◽  
Pain Patients

Healthcare costs associated with elderly chronic pain patients in primary care

2015 ◽  
Vol 71 (8) ◽  
pp. 939-947 ◽  
Author(s):  
Aida Lazkani ◽  
Tiba Delespierre ◽  
Bernard Bauduceau ◽  
Florence Pasquier ◽  
Philippe Bertin ◽  
...  
Keyword(s):  
Primary Care ◽  
Chronic Pain ◽  
Healthcare Costs ◽  
Chronic Pain Patients ◽  
Pain Patients

Pain Influences Several Levels of Attention

2005 ◽  
Vol 16 (4) ◽  
pp. 235-242 ◽  
Author(s):  
Astrid von Bueren Jarchow ◽  
Bogdan P. Radanov ◽  
Lutz Jäncke
Keyword(s):  
Chronic Pain ◽  
Divided Attention ◽  
Covert Attention ◽  
Attention Task ◽  
Attentional Deficits ◽  
Control Subjects ◽  
Chronic Pain Patients ◽  
Divided Attention Task ◽  
Pain Stimuli ◽  
Pain Patients

Abstract: The aim of the present study was to examine to what extent chronic pain has an impact on various attentional processes. To measure these attention processes a set of experimental standard tests of the “Testbatterie zur Aufmerksamkeitsprüfung” (TAP), a neuropsychological battery testing different levels of attention, were used: alertness, divided attention, covert attention, vigilance, visual search, and Go-NoGo tasks. 24 chronic outpatients and 24 well-matched healthy control subjects were tested. The control subjects were matched for age, gender, and education. The group of chronic pain patients exhibited marked deficiencies in all attentional functions except for the divided attention task. Thus, the data supports the notion that chronic pain negatively influences attention because pain patients` attention is strongly captivated by the internal pain stimuli. Only the more demanding divided attention task has the capability to distract the focus of attention to the pain stimuli. Therefore, the pain patients are capable of performing within normal limits. Based on these findings chronic pain patients' attentional deficits should be appropriately evaluated and considered for insurance and work related matters. The effect of a successful distraction away from the pain in the divided attention task can also open new therapeutic aspects.

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