scholarly journals Factors That May Affect Delayed Relief Of Trigeminal Neuralgia After Microneurosurgery And The Long-Term Outcomes Associated With Delayed Relief

2019 ◽  
Vol Volume 12 ◽  
pp. 2817-2823
Author(s):  
Zhu Deng ◽  
Ruiquan Liu ◽  
Yin Liu ◽  
Zheng Wang ◽  
Yanbing Yu ◽  
...  
Author(s):  
Takuro Inoue ◽  
Satoshi Shitara ◽  
Yukihiro Goto ◽  
Mustaqim Prasetya ◽  
Lori Radcliffe ◽  
...  

2018 ◽  
Vol 117 ◽  
pp. e300-e307 ◽  
Author(s):  
Adela Wu ◽  
Tina Doshi ◽  
Alice Hung ◽  
Tomas Garzon-Muvdi ◽  
Matthew T. Bender ◽  
...  

Neurosurgery ◽  
2016 ◽  
Vol 79 (6) ◽  
pp. 879-888 ◽  
Author(s):  
Nuria E. Martínez Moreno ◽  
Jorge Gutiérrez-Sárraga ◽  
Germán Rey-Portolés ◽  
Adolfo Jiménez-Huete ◽  
Roberto Martínez Álvarez

Abstract BACKGROUND: Gamma knife radiosurgery (GKRS) is one of the alternatives for treatment for classical trigeminal neuralgia (TN). OBJECTIVE: To retrospectively analyze long-term outcomes for TN using GKRS achieved at our institution. METHODS: One hundred seventeen patients with medically refractory TN treated by GKRS at our institution were followed up between 1993 and 2011. Mean maximum dose was 86.5 Gy (range: 80-90 Gy; median: 90 Gy). Clinical response was defined based on the Burchiel classification. We considered classes I and II as a complete response. For toxicity, we use the Barrow Neurological Institute facial numbness scale. Mean duration of follow-up was 66 months (range: 24-171 months). RESULTS: Complete response at last follow-up in our patients was 81%, with an excellent response while off medication in 52%. Pain-free rates without medication (class I) were 85% at 3 years (confidence interval [CI]: 78%-94%), 81% at 5 years (CI: 72%-91%), and 76% at 7 years (CI: 65%-90%). Complete response rates (classes I-II) were 91% at 3 years (CI: 86%-97%), 86% at 5 years (CI: 79%-93%), and 82% at 7 years (CI: 72%-93%). Poor treatment response rates differed significantly between patients who had undergone previous surgery and were refractory to management with medication prior to GKRS. New or worsening facial numbness was reported in 32.5% (30% score II and 2.5% score III). No anesthesia dolorosa was reported. Permanent recurrence pain rate was 12%. CONCLUSION: GKRS achieved favorable outcomes compared with surgery in terms of pain relief and complication rates in our cohort of patients, notwithstanding decreasing pain-free survival rates over time. We consider GKRS to be an initial treatment in the management of medically intractable TN in selected patients.


Neurosurgery ◽  
2016 ◽  
Vol 63 ◽  
pp. 175-176 ◽  
Author(s):  
Imran Noorani ◽  
O. Sparrow ◽  
Girish Vajramani

Neurosurgery ◽  
2006 ◽  
Vol 59 (2) ◽  
pp. 471
Author(s):  
Ron I. Riesenburger ◽  
Vasilios A. Zerris ◽  
Kevin C. Yao

Author(s):  
Xu-hui Wang ◽  
Chun Zhou ◽  
Guang-jian Shen ◽  
Min-hui Xu ◽  
Guang-xin Chen ◽  
...  

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