scholarly journals Comparison of the short-term outcomes after low-temperature plasma radiofrequency ablation (coblation) in the Gasserian ganglion for the treatment of idiopathic trigeminal neuralgia

2019 ◽  
Vol Volume 12 ◽  
pp. 1235-1242 ◽  
Author(s):  
Yan Li ◽  
Yuna Guo ◽  
Liqiang Yang ◽  
Jiaxiang Ni
Keyword(s):  
Radiofrequency Ablation ◽  
Low Temperature ◽  
Trigeminal Neuralgia ◽  
Gasserian Ganglion ◽  
Low Temperature Plasma ◽  
Short Term ◽  
Temperature Plasma ◽  
Idiopathic Trigeminal Neuralgia

Masticatory Dysfunction After Computed Tomography–Guided Plasma Ablation vs. Radiofrequency Ablation on Gasserian Ganglion for Idiopathic Trigeminal Neuralgia: A Randomized Controlled Trial

Pain Medicine ◽  
2020 ◽  
Author(s):  
Shuyue Zheng ◽  
Xiuhua Li ◽  
Liqiang Yang ◽  
Liangliang He ◽  
Guoqing Cao ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Trigeminal Neuralgia ◽  
Activity Index ◽  
Controlled Trial ◽  
Gasserian Ganglion ◽  
Idiopathic Trigeminal Neuralgia ◽  
Plasma Ablation ◽  
Masseter Muscles ◽  
Maximum Voltage ◽  
Anterior Temporalis

Abstract Objective We aimed to evaluate masticatory dysfunction after two different types of ablation on the Gasserian ganglion for the treatment of idiopathic trigeminal neuralgia. We hypothesized that low-temperature plasma radiofrequency ablation (LTP-RFA) was noninferior to radiofrequency thermocoagulation (RFT) with respect to initial efficacy. Methods In the randomized, single-blind, parallel-group, noninferiority trial, 204 participants with idiopathic trigeminal neuralgia were randomly allocated to receive plasma ablation in the LTP-RFA group and radiofrequency ablation in the RFT group in a 1:1 ratio, with random block sizes of four or six. Participants were examined at baseline (T0), on the day of discharge (T1), and at the 6-month follow-up (T2). The primary end point was the clinincal effective rate in the LTP-RFA group compared with that in the RFT group after intervention on the day of discharge. Noninferiority was prespecified at -10%. Results The intention-to-treat analysis revealed that the initial efficacy rates were 91.2% in LTP-RFA group and 93.1% in RFT group (rate ratio [RR] = 0.979, 95% confidence interval [CI]: 0.904–1.061, P = 0.795). The difference between the two groups was 1.9% (95% CI: -5.6% to 9.4%), which showed that LTP-RFA demonstrated noninferiority compared with RFT in initial efficacy. Compared with the RFT group, the LTP-RFA group exhibited a significantly greater improvement in the maximum voltage of the masseter muscles with mean differences of 11.40 (95% CI: 10.52 to 12.27, P < 0.001) at T1 and 17.41 (95% CI: 14.68 to 20.13, P < 0.001) at T2, respectively. Similar results were observed for the asymmetry index of occlusion, the maximum voltage of the anterior temporalis, and the activity index of anterior temporalis / masseter muscles. No serious adverse events were observed in either group. Conclusions Compared with the RFT group, noninferior efficacy for pain relief and improvement of masticatory function was revealed in the LTP-RFA group.

scholarly journals A Novel Endoscopic Nasopharyngectomy Technique Using Low-Temperature Plasma Radiofrequency Ablation with Piece Resection In Resectable Locally Recurrent Nasopharyngeal Carcinoma: Operative Video and Technical Nuances

2021 ◽  
Author(s):  
Xiong Zou ◽  
Yi-Jun Hua ◽  
You-Ping Liu ◽  
Yu-Long Xie ◽  
Yan-Feng Ouyang ◽  
...  
Keyword(s):  
Radiofrequency Ablation ◽  
Survival Rate ◽  
Nasopharyngeal Carcinoma ◽  
Low Temperature ◽  
Operation Time ◽  
Low Temperature Plasma ◽  
Temperature Plasma ◽  
Free Survival ◽  
Recurrent Nasopharyngeal Carcinoma ◽  
Locally Recurrent

Abstract Objectives: Endoscopic nasopharyngectomy (ENPG) with en bloc resection has been well accepted in resectable locally recurrent nasopharyngeal carcinoma (rNPC), but it is difficult to master the technique and disseminate. We designed a novel method using low-temperature plasma radiofrequency ablation (LPRA) with piece resection and evaluated the survival benefit.Materials and Methods: A total of 56 resectable rNPC patients were retrospectively analyzed, and the following factors were assessed: ratio of R0 margin, overall survival rate (OS), local relapse-free survival rate (LRFS), and progression-free survival rate (PFS).Results: All surgeries were successfully performed without any severe postoperative complications or deaths. The median operation time was 130 minutes (range, 32–280 minutes), with little blood loss (median, 30 ml; range, 5–500 ml). The average number of hospital days postoperation was 3 days (range, 2–5 days). All cases (100.0%) had R0 margins. The nasopharyngeal defects were completely re-epithelialized in 53 (94.6%) patients. The 2-year OS, LRFS, and PFS rates of the entire cohort were 100%, 90.7% and 88.6%, respectively. Multivariate Cox proportional hazards model analysis indicated that cycles of radiotherapy were independent risk factors for LRFS (hazard ratio [HR], 16.607; 95% CI 1.638–168.417; P = 0.017) and PFS (HR, 7.424; 95% CI 1.190–46.320; P = 0.032).Conclusions: Radical endoscopic nasopharyngectomy is a novel, safe and relatively easier method for treating resectable rNPC by using low-temperature plasma radiofrequency ablation with piece resection. However, further data and longer follow-up time are needed to prove its efficacy.

scholarly journals Low-temperature plasma radiofrequency ablation in phantom limb pain: A case report

2018 ◽  
Vol 4 (2) ◽  
pp. 62 ◽  
Author(s):  
Fei Li ◽  
Jiaxiang Ni ◽  
Hongyan Li ◽  
Yan Li ◽  
Zhaoxuan Guo ◽  
...  
Keyword(s):  
Case Report ◽  
Radiofrequency Ablation ◽  
Low Temperature ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Low Temperature Plasma ◽  
Limb Pain ◽  
Temperature Plasma

scholarly journals Plasma Modification of Carbon Coating Produced by RF CVD on Oxidized NiTi Shape Memory Alloy under Glow-Discharge Conditions

Materials ◽  
2021 ◽  
Vol 14 (17) ◽  
pp. 4842
Author(s):  
Justyna Witkowska ◽  
Michał Tarnowski ◽  
Emilia Choińska ◽  
Marek Kulpa ◽  
Jacek Szade ◽  
...  
Keyword(s):  
Low Temperature ◽  
Glow Discharge ◽  
Amorphous Carbon ◽  
Carbon Coating ◽  
Chemical Vapour ◽  
Contact Angles ◽  
Plasma Modification ◽  
Low Temperature Plasma ◽  
Short Term ◽  
Temperature Plasma

Our previous work has shown that for cardiac applications, combining low-temperature plasma oxidation with an amorphous carbon coating (a-C:N:H type) constitutes a prospective solution. In this study, a short-term modification by low-temperature oxygen plasma is proposed as an example and a method for shaping the topography and surface energy of the outer amorphous carbon coating, produced via the Radio-Frequency Chemical Vapour Deposition (RFCVD) method on NiTi alloy oxidized under glow-discharge conditions. This treatment alters the chemical composition of the outer zone of the surface layer. A slight increase is also noted in the surface roughness at the nanoscale. The contact angles were shown to increase by about 20% for water and 30% for diiodomethane, while the surface free energy decreased by ca. 11%. The obtained results indicate that even short-term contact with low-temperature plasma can shape the surface properties of the carbon coating, an outcome which shows potential in terms of its use in medical applications.

scholarly journals A Novel Endoscopic Nasopharyngectomy Technique Using Low-Temperature Plasma Radiofrequency Ablation with Piece Resection In Resectable Locally Recurrent Nasopharyngeal Carcinoma: Operative Video and Technical Nuances

2022 ◽  
Keyword(s):  
Radiofrequency Ablation ◽  
Nasopharyngeal Carcinoma ◽  
Low Temperature ◽  
Full Text ◽  
Low Temperature Plasma ◽  
Temperature Plasma ◽  
Recurrent Nasopharyngeal Carcinoma ◽  
Locally Recurrent

Abstract The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.

scholarly journals Carbon Dioxide Laser Microsurgery versus Low-Temperature Plasma Radiofrequency Ablation for T1a Glottic Cancer: A Single-Blind Randomized Clinical Trial

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Yan Zhang ◽  
Binru Wang ◽  
Guangbin Sun ◽  
Guoliang Zhang ◽  
Ling Lu ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Overall Survival ◽  
Radiofrequency Ablation ◽  
Low Temperature ◽  
Carbon Dioxide Laser ◽  
Survival Rates ◽  
Glottic Cancer ◽  
Low Temperature Plasma ◽  
Temperature Plasma ◽  
Overall Survival Rates

Background. Very few studies have been conducted to compare carbon dioxide laser microsurgery (CO2-LS) with low-temperature plasma radiofrequency ablation (LTP-RFA) in treating T1a glottic cancer. Therefore, we conducted this study to compare the efficacy of CO2-LS and LTP-RFA to define a superior therapeutic modality for T1a glottic cancer.Methods. Patients (n=131) with T1a glottic cancer were recruited between January 2010 and September 2014. The included patients were randomly assigned to either receive CO2-LS (n=65) or LTP-RFA (n=66). We conducted the following multidimensional vocal assessments: (i) videostroboscopic evaluation; (ii) auditory-perceptual evaluation; (iii) aerodynamics/ efficiency; (iv) acoustics; and (v) self-assessment questionnaires. Meanwhile, the surgery time and three-year overall survival rates in two groups were recorded. The predefined primary endpoint was overall survival, and the minimum follow-up time was set to six months.Results. After treatment, we found that the structure and vibration of vocal cord might recover more quickly in patients receiving LTP-RFA than in patients receiving CO2-LS, and moreover, the patients in the LTP-RFA group had the better vocal functions. Meanwhile, the surgery time was significantly less in the LTP-RFA group (8.83±1.59 minutes) than in the CO2-LS group (12.49±1.40 minutes) (p<0.00001). In addition, the two intervention methods had the similar three-year overall survival rates (94% versus 96%, p=0.58).Conclusion. These results indicated that both LTP-RFA and CO2-LS could effectively treat T1a glottic cancer, and LTP-RFA might have some advantages in voice function. Limited by the relatively small sample size, future studies were needed to validate our conclusion.

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