scholarly journals Effect of patient-controlled epidural analgesia versus patient-controlled intravenous analgesia on postoperative pain management and short-term outcomes after gastric cancer resection: a retrospective analysis of 3,042 consecutive patients between 2010 and 2015

2018 ◽  
Vol Volume 11 ◽  
pp. 1743-1749 ◽  
Author(s):  
Liping Wang ◽  
Xuan Li ◽  
Hong Chen ◽  
Jie Liang ◽  
Yu Wang
Keyword(s):  
Gastric Cancer ◽  
Pain Management ◽  
Postoperative Pain ◽  
Epidural Analgesia ◽  
Retrospective Analysis ◽  
Postoperative Pain Management ◽  
Short Term ◽  
Cancer Resection ◽  
Intravenous Analgesia ◽  
Gastric Cancer Resection

scholarly journals A Comparison of the Effects of Epidural Analgesia Versus Traditional Pain Management on Outcomes After Gastric Cancer Resection

2014 ◽  
Vol 39 (3) ◽  
pp. 200-207 ◽  
Author(s):  
Kenneth C. Cummings ◽  
Meatal Patel ◽  
Phyo Than Htoo ◽  
Paul M. Bakaki ◽  
Linda C. Cummings ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Pain Management ◽  
Epidural Analgesia ◽  
Cancer Resection ◽  
Gastric Cancer Resection

scholarly journals Analysis of Prognostic Factors Affecting Short-term and Long-term Outcomes of Gastric Cancer Resection

2021 ◽  
Vol 41 (7) ◽  
pp. 3523-3534
Author(s):  
PIOTR KULIG ◽  
PRZEMYSŁAW NOWAKOWSKI ◽  
MAREK SIERZĘGA ◽  
RADOSŁAW PACH ◽  
OLIWIA MAJEWSKA ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Prognostic Factors ◽  
Long Term Outcomes ◽  
Short Term ◽  
Factors Affecting ◽  
Cancer Resection ◽  
Gastric Cancer Resection

Ketamine Improves the Management of Exaggerated Postoperative Pain Observed in Perioperative Fentanyl-treated Rats

2005 ◽  
Vol 102 (2) ◽  
pp. 421-428 ◽  
Author(s):  
Philippe Richebé ◽  
Cyril Rivat ◽  
Jean-Paul Laulin ◽  
Pierre Maurette ◽  
Guy Simonnet
Keyword(s):  
Pain Management ◽  
Postoperative Pain ◽  
Weight Bearing ◽  
Experimental Studies ◽  
Postoperative Pain Management ◽  
Opioid Use ◽  
Short Term ◽  
Postoperative Rehabilitation ◽  
Pain Hypersensitivity ◽  
Plantar Incision

Background Although opioids are unsurpassed analgesics, experimental and clinical studies suggest that opioids activate N-methyl-d-aspartate pronociceptive systems leading to pain hypersensitivity and short-term tolerance. Because it is difficult in humans to differentiate pain from hyperalgesia during the postoperative period, the authors performed experimental studies with fentanyl using the rat incisional pain model for evaluating relations between hyperalgesia and short-term tolerance. Because N-methyl-d-aspartate receptor antagonists oppose both pain hypersensitivity and tolerance induced by opioids, the authors examined the capability of ketamine for improving exaggerated postoperative pain management. Methods During halothane anesthesia, a hind paw plantar incision was performed in rats receiving four fentanyl subcutaneous injections (100 microg/kg per injection, every 15 min). In some groups, three subcutaneous ketamine injections (10 mg/kg per injection, every 5 h) were performed in saline- or fentanyl-treated rats. One day after surgery, the analgesic effect of morphine (2 mg/kg subcutaneous) was tested. Analgesia, mechanical hyperalgesia, tactile allodynia, and pain score were assessed for several days using the paw pressure vocalization test, the von Frey application test, and the postural disequilibrium test. Results Fentanyl induced analgesia but also produced exaggerated postoperative pain as indicated by the enhancement of hyperalgesia, allodynia, and weight-bearing decrease after hind paw plantar incision. Ketamine pretreatment prevented such a fentanyl-induced enhancement of postoperative pain and improved its management by morphine. Conclusions By opposing postoperative pain hypersensitivity and subsequent short-term tolerance induced by perioperative opioid use, ketamine not only improves exaggerated postoperative pain management but also provides better postoperative rehabilitation.

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