scholarly journals Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite

2008 ◽  
pp. 41 ◽  
Author(s):  
Hironori Tsuchiya
Keyword(s):  
Local Anesthetic ◽  
Anesthetic Failure

Local anesthetic failure in endodontics:

2002 ◽  
Vol 1 (1) ◽  
pp. 26-39 ◽  
Author(s):  
Kenneth M. Hargreaves ◽  
Karl Keiser
Keyword(s):  
Local Anesthetic ◽  
Anesthetic Failure

scholarly journals Tackling Local Anesthetic Failure in Endodontics

2021 ◽  
Author(s):  
Krishnamachari Janani ◽  
Kavalipurapu Venkata Teja ◽  
Harini K ◽  
Kaligotla Apoorva Vasundhara ◽  
Jerry Jose
Keyword(s):  
Sodium Channel ◽  
Local Anesthesia ◽  
Local Anesthetic ◽  
Endodontic Treatment ◽  
Nerve Membrane ◽  
Inflammatory Conditions ◽  
Base Form ◽  
Anesthetic Failure ◽  
Mandibular Teeth ◽  
Irreversible Pulpitis

Achieving anesthesia in a hot tooth or tooth with inflamed pulp is challenging, especially during endodontic treatment. In the presence of symptomatic irreversible pulpitis, mainly in mandibular teeth, pose even more challenge to attain profound anesthesia. Tetradoxin resistant channel is a class of sodium channel that is found to be increased in such condition and is found to resist local anesthesia. The pH also determines the success of local anesthesia. In inflammatory conditions, the surrounding area\'s pH, which eventually decreases the amount of base form of local anesthetic penetration into the nerve membrane, thereby causing anesthetic failure. In such conditions, the excitability threshold is reduced, leading to failure in achieving anesthesia. This chapter highlights and discusses the cause of anesthetic failure and its management in obtaining profound anesthesia during endodontic treatment.

Local Anesthetic Action of Aqueous Extract of Citrullous Colocynthis Fruit on Rabbit Cornea

2012 ◽  
Vol 3 (4) ◽  
pp. 209-211
Author(s):  
Dr.T.Jayasree Dr.T.Jayasree ◽  
◽  
Dr Shaikh Ubedulla ◽  
Dr. Chandrasekhar Nutalapati ◽  
Naveen Aalasyam ◽  
...  
Keyword(s):  
Aqueous Extract ◽  
Local Anesthetic ◽  
Rabbit Cornea ◽  
Anesthetic Action

A Case of Takotsubo Cardiomyopathy after Injection of a Local Anesthetic Containing Epinephrine

2014 ◽  
Vol 76 (3) ◽  
pp. 222-224 ◽  
Author(s):  
Hiroko TSURU ◽  
Hiroshi UCHI ◽  
Reiko ITO ◽  
Misa NAKANO ◽  
Futoshi KODA ◽  
...  
Keyword(s):  
Takotsubo Cardiomyopathy ◽  
Local Anesthetic

Local Anesthetics – Substances with Multiple Application in Medicine

2016 ◽  
Vol 4 (1) ◽  
pp. 17
Author(s):  
Rodica Sîrbu ◽  
Emin Cadar ◽  
Cezar Laurențiu Tomescu ◽  
Cristina Luiza Erimia ◽  
Stelian Paris ◽  
...  
Keyword(s):  
Peripheral Nerve ◽  
Medical Care ◽  
Local Anesthesia ◽  
Short Duration ◽  
Local Anesthetic ◽  
Local Anesthetics ◽  
Nerve Roots ◽  
Nervous Control ◽  
Painful Sensation ◽  
Action Groups

Local anesthetics are substances which, by local action groups on the runners, cause loss of reversible a painful sensation, delimited corresponding to the application. They allow small surgery, short in duration and the endoscopic maneuvers. May be useful in soothe teething pain of short duration and in the locking of the nervous disorders in medical care. Local anesthesia is a process useful for the carrying out of surgery and of endoscopic maneuvers, to soothe teething pain in certain conditions, for depriving the temporary structures peripheral nervous control. Reversible locking of the transmission nociceptive, the set of the vegetative and with a local anesthetic at the level of the innervations peripheral nerve, roots and runners, a trunk nervous, around the components of a ganglion or coolant is cefalorahidian practice anesthesia loco-regional. Local anesthetics summary and semi-summary have multiple applications in dentistry, consulting, surgery and obstetrics, constituting "weapons" very useful in the fight against the pain.

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