scholarly journals Journal of Inflammation Research

10.2147/jir ◽  
2020 ◽  
Keyword(s):  
Inflammation Research

scholarly journals Report of 3rd annual conference of Society of Inflammation Research

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Jyotirmay Biswas ◽  
M Balasubramanyam ◽  
Nivedita Chatterjee
Keyword(s):  
Annual Conference ◽  
Inflammation Research

scholarly journals Taenia solium Cysticercosis and Its Impact in Neurological Disease

2020 ◽  
Vol 33 (3) ◽  
Author(s):  
Hector H. Garcia ◽  
Armando E. Gonzalez ◽  
Robert H. Gilman
Keyword(s):  
Taenia Solium ◽  
Developed Countries ◽  
Brain Inflammation ◽  
Inflammation Research ◽  
Content Type ◽  
Molecular Assays ◽  
Genome Data ◽  
Porcine Cysticercosis ◽  
Neurological Morbidity ◽  
And Control

SUMMARY Taenia solium neurocysticercosis (NCC) is endemic in most of the world and contributes significantly to the burden of epilepsy and other neurological morbidity. Also present in developed countries because of immigration and travel, NCC is one of few diseases targeted for eradication. This paper reviews all aspects of its life cycle (taeniasis, porcine cysticercosis, human cysticercosis), with a focus on recent advances in its diagnosis, management, and control. Diagnosis of taeniasis is limited by poor availability of immunological or molecular assays. Diagnosis of NCC rests on neuroimaging findings, supported by serological assays. The treatment of NCC should be approached in the context of the particular type of infection (intra- or extraparenchymal; number, location, and stage of lesions) and has evolved toward combined symptomatic and antiparasitic management, with particular attention to modulating inflammation. Research on NCC and particularly the use of recently available genome data and animal models of infection should help to elucidate mechanisms of brain inflammation, damage, and epileptogenesis.

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