scholarly journals Aspirin as an Adjunctive Pharmacologic Therapy Option for COVID-19: Anti-Inflammatory, Antithrombotic, and Antiviral Effects All in One Agent

2021 ◽  
Vol Volume 13 ◽  
pp. 957-970
Author(s):  
Udaya S Tantry ◽  
Karsten Schror ◽  
Eliano Pio Navarese ◽  
Young-Hoon Jeong ◽  
Jacek Kubica ◽  
...  
2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Amila Omeragic ◽  
Nareg Kara-Yacoubian ◽  
Jennifer Kelschenbach ◽  
Cigdem Sahin ◽  
Carolyn L. Cummins ◽  
...  

2020 ◽  
Vol 12 (3) ◽  
pp. 205-209
Author(s):  
S. Manav ◽  
M. Yilmaz ◽  
H. Baytekin ◽  
K. Çelik ◽  
A. Çağli

Abstract. The purpose of the present study was to review scientific reports on propolis used in livestock, to analyze them and to make appropriate summaries and conclusions. Propolis is a natural resinous substance collected by honey bees (Apis mellifera L.) from different plant parts such as buds, branches, leaves and exudates. Propolis is a known source of polyphenols and the flavonoids which have been widely studied as biochemical markers for botanical origin and to explain their antioxidant capacity as a key factor in chemoprevention. Antimicrobial, anti-inflammatory and anticancer biological activities of propolis are known. Propolis has been used as a remedy in traditional medicine systems all over the world, mainly to treat wounds, burns, sore throat and stomach ulcer, etc. Modern science has confirmed the antimicrobial and antiviral action of propolis and has discovered numerous other beneficial pharmacological properties of bee glue: immunomodulating, anti-inflammatory, antiobesity, antitumor, and many others. For this reason, a significant number of products containing propolis have been developed and commercialized: medical devices, over-the-counter preparations, health foods and beverages, cosmetics. Recently, studies on the effects of propolis on animal husbandry and animal health have increased due to many issues, such as organic animal breeding, feeding or treatment methods, reducing the use of antibiotics. One of these areas is the use of propolis to improve the growth performance and productivity of the livestock. Propolis has been determined to have antibacterial and antiviral effects in humans and animals.


Life Sciences ◽  
2005 ◽  
Vol 76 (10) ◽  
pp. 1135-1146 ◽  
Author(s):  
Ming-Jiuan Wu ◽  
Ching-Yi Weng ◽  
Hsiou-Yu Ding ◽  
Pei-Jong Wu

2013 ◽  
Vol 4 ◽  
Author(s):  
Salda�a Morales Fatima ◽  
Lozada Requena Ivan ◽  
Zegarra Ruiz Daniel ◽  
D�vila Paico Silvia ◽  
AGUILAR JOSE

2017 ◽  
Vol 6 (3) ◽  
pp. 54-61
Author(s):  
Jarosław Wysocki

Acute and chronic rhinosinusitis is the most common problem encountered in ENT practice. Nearly all cases of acute rhinosinusitis are of viral background. Further course of the disease is determined by the condition of mucosal membranes, systemic immune strength, virulence of the infectious agent and the morphology of paranasal sinuses. Medications used in acute rhinosinusitis provide symptomatic treatment, their effect being aimed at reduction of inflammation and swelling. Products obtained from medicinal plants may provide an alternative to these medications. In vitro studies have shown that these products demonstrate anti-inflammatory, immunostimulating, anti-edemic, and antiviral effects. With the market placement of Sinupret extract, the armamentarium of therapeutic has been extended by a concentrated product characterized by strength comparable to that of synthetic analgesic and anti-inflammatory drug as well as by additional, documented antiviral effect. The article discusses the composition of Sinupret extract, the mechanisms of action of its active substances, and the results of preclinical and clinical studies of Sinupret and Sinupret extract.


2019 ◽  
Vol 118 ◽  
pp. 109271 ◽  
Author(s):  
Yu-Ting Liao ◽  
Shih-Min Wang ◽  
Shun-Hua Chen

Author(s):  
Arezoo Rezazadeh ◽  
Sara Sadeghzadeh ◽  
Kosar Namakin ◽  
Atena Tamimi ◽  
Zahra Khanjani

Destructive outcomes of coronavirus pandemic call for medical research which can report all of the influential agents not only for the treatment of the disease but also preventing its severe impacts on the societal health in the most efficient manner. Zinc plays an integral role in the function of cellular enzymes and transcription factors. Owing to its anti-inflammatory and cellular immunity regulation activity, zinc is regarded to be effective on strengthening the immune system. Its crucial antiviral effects have long been established as well. Studies suggest that low serum zinc level predisposes the patient to severe COVID-19 infection, which makes patient’s zinc profile a potential determinant of prognosis and severity of this disease. Furthermore, zinc supplementation has indicated promising outcomes of coronavirus infection management. Zinc modulates cell-mediated immunity and participates in the killing of microorganisms in cytotoxic immune cells. Zn2 + has anti-inflammatory effects by inhibiting IL-6 production. Although there is still not enough evidence, it seems that zinc could be a promising supplementary treatment for COVID-19 especially in zinc-deficient patients. The aim of this review is to clarify the role of zinc in pathogenesis and therapy of COVID-19 in detail.


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