scholarly journals High Use of Antidepressant Medication in Both Mild-to-Modelate and Possible Severe Asthma – A Nationwide Cohort Study

2022 ◽  
Vol Volume 15 ◽  
pp. 13-23
Author(s):  
Kjell Erik Julius Håkansson ◽  
Martino Renzi-Lomholt ◽  
Vibeke Backer ◽  
Charlotte Suppli Ulrik
Keyword(s):  
Cohort Study ◽  
Severe Asthma ◽  
Antidepressant Medication

scholarly journals Factors associated with re-initiation of antidepressant treatment following discontinuation during pregnancy: a register-based cohort study

2020 ◽  
Vol 23 (5) ◽  
pp. 709-717
Author(s):  
Anna Wikman ◽  
Alkistis Skalkidou ◽  
Anna-Karin Wikström ◽  
Erik Lampa ◽  
Michael S. Kramer ◽  
...  
Keyword(s):  
Cohort Study ◽  
Psychiatric Illness ◽  
Antidepressant Treatment ◽  
Nordic Country ◽  
Antidepressant Medication ◽  
High Educational Level ◽  
Maternal Characteristics ◽  
Discontinuation Of Treatment ◽  
Antidepressant Use ◽  
High Educational

Abstract Antidepressant treatment when facing a pregnancy is an important issue for many women and their physicians. We hypothesized that women with a greater burden of pre-pregnancy psychiatric illness would be more likely to re-initiate antidepressants following discontinuation of treatment during pregnancy. A register-based cohort study was carried out including 38,595 women who gave birth between the 1st of January 2007 and the 31st of December 2014, who had filled a prescription for an antidepressant medication in the year prior to conception. Logistic regressions were used to explore associations between maternal characteristics and antidepressant treatment discontinuation or re-initiation during pregnancy. Most women discontinued antidepressant treatment during pregnancy (n = 29,095, 75.4%), of whom nearly 12% (n = 3434, 11.8%) re-initiated treatment during pregnancy. In adjusted analyses, parous women (aOR 1.22, 95% CI 1.12–1.33), with high educational level (aOR 1.21, 95% CI 1.08–1.36); born within the EU (excluding Nordic countries, aOR 1.41, 95% CI 1.03–1.92) or a Nordic country (aOR 1.42, 95% CI 1.22–1.65); who more often reported prior hospitalizations due to psychiatric disorders (aOR 1.50, 95% CI 1.10–2.03, for three or more episodes); and had longer duration of pre-pregnancy antidepressant use (aOR 6.10, 95% CI 5.48–6.77, for >2 years antidepressant use), were more likely to re-initiate antidepressants than were women who remained off treatment. Women with a greater burden of pre-pregnancy psychiatric illness were more likely to re-initiate antidepressants. Thus, pre-pregnancy psychiatric history may be particularly important for weighing the risks and benefits of discontinuing antidepressants during pregnancy.

scholarly journals A retrospective cohort study in severe asthma describing commonly measured biomarkers: Eosinophil count and IgE levels

2018 ◽  
Vol 134 ◽  
pp. 117-123 ◽  
Author(s):  
John Haughney ◽  
Alyn Morice ◽  
Kevin G. Blyth ◽  
Amanda J. Lee ◽  
Alasdair Coutts ◽  
...  
Keyword(s):  
Cohort Study ◽  
Severe Asthma ◽  
Retrospective Cohort Study ◽  
Eosinophil Count ◽  
Retrospective Cohort

Longitudinal association of antidepressant medication use with metabolic syndrome: Results of a 9-year follow-up of the D.E.S.I.R. cohort study

2016 ◽  
Vol 74 ◽  
pp. 34-45 ◽  
Author(s):  
Marine Azevedo Da Silva ◽  
Beverley Balkau ◽  
Ronan Roussel ◽  
Jean Tichet ◽  
Frédéric Fumeron ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Medication Use ◽  
Antidepressant Medication ◽  
Longitudinal Association
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