scholarly journals Clinical impact of a pharmacist-led inpatient anticoagulation service: a review of the literature

Author(s):  
Tiffany Lee ◽  
Erin Davis ◽  
Jason Kielly
2017 ◽  
Vol 22 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Bastianina Contena ◽  
Stefano Taddei

Abstract. Borderline Intellectual Functioning (BIF) refers to a global IQ ranging from 71 to 84, and it represents a condition of clinical attention for its association with other disorders and its influence on the outcomes of treatments and, in general, quality of life and adaptation. Furthermore, its definition has changed over time causing a relevant clinical impact. For this reason, a systematic review of the literature on this topic can promote an understanding of what has been studied, and can differentiate what is currently attributable to BIF from that which cannot be associated with this kind of intellectual functioning. Using Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) criteria, we have conducted a review of the literature about BIF. The results suggest that this condition is still associated with mental retardation, and only a few studies have focused specifically on this condition.


2016 ◽  
Vol 32 (7) ◽  
pp. 448-452 ◽  
Author(s):  
Kathleen Gibson ◽  
Neil Khilnani ◽  
Marlin Schul ◽  
Mark Meissner

The American College of Phlebology Guidelines Committee performed a systematic review of the literature regarding the clinical impact and treatment of incompetent accessory saphenous veins. Using an accepted process for guideline developments, we developed a consensus opinion that patients with symptomatic incompetence of the accessory great saphenous veins (anterior and posterior accessory saphenous veins) be treated with endovenous thermal ablation (laser or radiofrequency) or ultrasound-guided foam sclerotherapy to eliminate symptomatology (Recommendation Grade 1C).


2015 ◽  
Vol 38 (6) ◽  
pp. 687-691 ◽  
Author(s):  
Konstantinos Natsis ◽  
Trifon Totlis ◽  
Angeliki Chorti ◽  
Marinos Karanassos ◽  
Matthaios Didagelos ◽  
...  

2009 ◽  
Vol 19 (2) ◽  
pp. 245-248 ◽  
Author(s):  
Frédéric Amant ◽  
An Coosemans ◽  
Vincent Renard ◽  
Els Everaert ◽  
Ignace Vergote

AbstractThe clinical impact of ET-743 (trabectedin; Yondelis) in women with leiomyosarcoma and undifferentiated uterine sarcoma in patients previously treated with chemotherapy is investigated. Current data show a clinical benefit in 2/5 patients, of which 1 had a partial remission during 9 months. Pooling the treatment outcomes with literature data, a response in 5 (38%) of 13 patients and a clinical benefit in 7 (54%) of 13 patients for all high-grade uterine sarcomas is calculated. When only uterine leiomyosarcomas are concerned, response rate is 5 (45%) of 11 patients with a clinical benefit in 7 (64%) of 11 patients. These results on the use of ET-743 in uterine sarcoma patients support the conductance of larger trials.


2020 ◽  
Vol 10 (6-7) ◽  
pp. 122-123
Author(s):  
Maurits Wondergem ◽  
Friso M. van der Zant ◽  
Wouter A. M. Broos ◽  
Remco J. J. Knol

In the article ‘Clinical impact of PSMA PET in biochemically recurrent prostate cancer; a review of the literature’ (Tijdschrift voor Urologie, October 2020), the column headings of Tab. 3 are missing. The complete table is presented …


2020 ◽  
Vol 10 (6-7) ◽  
pp. 109-121 ◽  
Author(s):  
Maurits Wondergem ◽  
Friso M. van der Zant ◽  
Wouter A. M. Broos ◽  
Remco J. J. Knol

Abstract PSMA PET is increasingly used for localising biochemical recurrent prostate cancer (BCR) and is incorporated in European and national guidelines. Nevertheless, clinical implications of PSMA PET need to be clarified. In this report, the available literature on the clinical impact of PSMA PET in patients with BCR is reviewed. A comprehensive literature search was performed using the MEDLINE® database. All studies reporting data on PSMA PET directed patient management were considered relevant. In the review, 16 studies were included. Change of management was 45% for the pooled data (861/1899 patients), of which 50% changed from non-targeted to targeted approach. Change from targeted to non-targeted approaches was found in 17% of patients. High heterogeneity was found between presently available studies. It can be concluded that PSMA PET induces change of management in almost half of the patients with BCR. After PSMA PET more patients are selected for metastasis targeted therapies. Potential beneficial effects of metastasis directed therapies require further evaluation.


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