scholarly journals An unexpected complication of chronic myelomonocytic leukemia: severe renal failure due to malignant tubulo-interstitial cell infiltration

2015 ◽  
pp. 1 ◽  
Author(s):  
Jerrold Spapen ◽  
Karel Fostier ◽  
Hendrik De Raeve ◽  
Peter Janssens ◽  
Herbert Spapen
Keyword(s):  
Renal Failure ◽  
Interstitial Cell ◽  
Chronic Myelomonocytic Leukemia ◽  
Cell Infiltration ◽  
Severe Renal Failure ◽  
Myelomonocytic Leukemia

Platelet Function and the Bleeding Time in Progressive Renal Failure

1988 ◽  
Vol 60 (01) ◽  
pp. 083-087 ◽  
Author(s):  
M P Gordge ◽  
R W Faint ◽  
P B Rylance ◽  
G H Neild
Keyword(s):  
Renal Failure ◽  
Platelet Aggregation ◽  
Platelet Function ◽  
Bleeding Time ◽  
C Reactive Protein ◽  
Severe Renal Failure ◽  
Reactive Protein ◽  
Thromboxane Production ◽  
Von Willebrand ◽  
Willebrand Factor

SummaryBleeding time and platelet function tests were performed on 31 patients with progressive chronic renal failure (CRF) due to non-immunological (urological) causes, and compared with 22 healthy controls. Patients were classified as mild (plasma creatinine <300 μmol/l), moderate (300-600 μmol/l) or severe renal failure (>600 μmol/l). Bleeding time was rarely prolonged in mild and moderate CRF and mean bleeding time significantly elevated only in severe CRF (p <0.005). Haematocrit was the only index which correlated with bleeding time (r = -0.40). Platelet counts, collagen stimulated thromboxane generation, and platelet aggregation responses to ADP, collagen and ristocetin were all either normal or increased in all three CRF groups, but thromboxane production in clotting blood was reduced. Plasma fibrinogen, C reactive protein and von Willebrand factor (vWF) were elevated in proportion to CRF. We found no evidence that defects in platelet aggregation or platelet interaction with vWF prolong the bleeding time in patients with progressive CRF.

scholarly journals Vasculitis associated with myelodysplastic syndrome and chronic myelomonocytic leukemia: French multicenter case-control study

2020 ◽  
Vol 50 (5) ◽  
pp. 879-884
Author(s):  
Anne Laure Roupie ◽  
Alexis Guedon ◽  
Benjamin Terrier ◽  
Constance Lahuna ◽  
Vincent Jachiet ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Chronic Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia ◽  
Control Study

Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia

2006 ◽  
Vol 30 (8) ◽  
pp. 1043-1047 ◽  
Author(s):  
M. Daskalakis ◽  
N. Mauritzson ◽  
B. Johansson ◽  
K. Bouabdallah ◽  
F. Onida ◽  
...  
Keyword(s):  
Chromosomal Abnormality ◽  
Chronic Myelomonocytic Leukemia ◽  
Myelomonocytic Leukemia
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