scholarly journals Advanced Chronic Kidney Disease is a Strong Predictor of Hypogonadism and is Associated with Decreased Lean Tissue Mass

2020 ◽  
Vol Volume 13 ◽  
pp. 319-327
Author(s):  
Ryszard Skiba ◽  
Anna Matyjek ◽  
Tomasz Syryło ◽  
Stanisław Niemczyk ◽  
Aleksandra Rymarz
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Strong Predictor ◽  
Lean Tissue ◽  
Tissue Mass ◽  
Advanced Chronic Kidney Disease ◽  
Lean Tissue Mass

scholarly journals Low lean tissue mass is an independent risk factor for mortality in patients with stages 4 and 5 non-dialysis chronic kidney disease

2017 ◽  
Vol 10 (2) ◽  
pp. 170-175 ◽  
Author(s):  
Almudena Vega ◽  
Soraya Abad ◽  
Nicolás Macías ◽  
Inés Aragoncillo ◽  
Alba Santos ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Risk Factor ◽  
Kidney Disease ◽  
Independent Risk Factor ◽  
Lean Tissue ◽  
Tissue Mass ◽  
Lean Tissue Mass

scholarly journals Body Composition of Chronic Kidney Disease Patients

2021 ◽  
Vol 5 (1) ◽  
pp. 54-58
Author(s):  
Anjani Bakshi ◽  
Kalyani Singh ◽  
Anupa Siddhu
Keyword(s):  
Chronic Kidney Disease ◽  
Body Composition ◽  
Adipose Tissue ◽  
Kidney Disease ◽  
Fat Tissue ◽  
Lean Tissue ◽  
Tissue Mass ◽  
Lean Tissue Mass ◽  
Significant Difference ◽  
Adipose Tissue Mass

With accelerated muscle proteolysis, a decrease in muscle mass is evident in chronic kidney disease (CKD) patients. This eventually leads to nutritional disturbance that for a long has been mostly attributed to malnutrition. This predisposes patients to premature morbidity and mortality. Assessing body composition, thus, becomes vital. In this cross-sectional study, CKD patients (n = 47) of stages 2, 3a, 3b and 4 were assessed for their lean tissue mass, adipose tissue mass and overhydration by body composition monitor. Lean tissue index and fat tissue index were calculated as lean tissue mass and adipose tissue mass in kilogram divided by patients’ height in square meters. Patients were assessed for their handgrip strength (HGS) by Jamar hydraulic hand dynamometer, and also for their 7-day diet history. Mean lean tissue index of CKD patients was 11.73 ± 2.49 kg/m2. About 34 (72.3%) out of 47 patients were below the reference value of lean tissue index. A significant difference in lean tissue index (P = 0.03) was observed at various stages. Patients at stage 4 had the lowest lean tissue index. Lean tissue was significantly (P = 0.03) low in patients consuming protein <0.6 gm/kg/day. All 47 patients had less than normal HGS values. Patients’ mean fat tissue index was 14.86 ± 6.18 kg/m2 and had water retention with a mean overhydration of 1.47 ± 2.12 L. CKD patients were malnourished with a significant low lean tissue index. Dietary protein intake and HGS of these patients were positively associated with lean tissue index.

Phosphate binders in patients with chronic kidney disease: Between the new and the old.

2019 ◽  
pp. 2-3
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Estimated Glomerular Filtration Rate ◽  
Chronic Kidney Disease Stage ◽  
Disease Stage ◽  
Phosphate Binders ◽  
Advanced Chronic Kidney Disease ◽  
Phosphate Retention ◽  
Stage 4 ◽  
Dietary Phosphate

Impaired phosphate excretion by the kidney leads to Hyperphosphatemia. It is an independent predictor of cardiovascular disease and mortality in patients with advanced chronic kidney disease (stage 4 and 5) particularly in case of dialysis. Phosphate retention develops early in chronic kidney disease (CKD) due to the reduction in the filtered phosphate load. Overt hyperphosphatemia develops when the estimated glomerular filtration rate (eGFR) falls below 25 to 40 mL/min/1.73 m2. Hyperphosphatemia is typically managed with oral phosphate binders in conjunction with dietary phosphate restriction. These drugs aim to decrease serum phosphate by binding ingested phosphorus in the gastrointestinal tract and its transformation to non-absorbable complexes [1].

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