scholarly journals An efficient PEGylated liposomal nanocarrier containing cell-penetrating peptide and pH-sensitive hydrazone bond for enhancing tumor-targeted drug delivery

2015 ◽  
pp. 6199 ◽  
Author(s):  
Ying Xie ◽  
Yuan Ding ◽  
Dan Sun ◽  
GuiLing Wang ◽  
HongGe Yang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Ph Sensitive ◽  
Cell Penetrating Peptide ◽  
Hydrazone Bond ◽  
Cell Penetrating ◽  
Targeted Drug

Amphiphilic multi-arm-block copolymer conjugated with doxorubicin via pH-sensitive hydrazone bond for tumor-targeted drug delivery

Biomaterials ◽  
2009 ◽  
Vol 30 (29) ◽  
pp. 5757-5766 ◽  
Author(s):  
Mani Prabaharan ◽  
Jamison J. Grailer ◽  
Srikanth Pilla ◽  
Douglas A. Steeber ◽  
Shaoqin Gong
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Targeted Drug Delivery ◽  
Ph Sensitive ◽  
Hydrazone Bond ◽  
Targeted Drug

Activable Cell-Penetrating Peptide Conjugated Prodrug for Tumor Targeted Drug Delivery

2015 ◽  
Vol 7 (29) ◽  
pp. 16061-16069 ◽  
Author(s):  
Hong Cheng ◽  
Jing-Yi Zhu ◽  
Xiao-Ding Xu ◽  
Wen-Xiu Qiu ◽  
Qi Lei ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Targeted Drug

pH-Sensitive ZnO Quantum Dots–Doxorubicin Nanoparticles for Lung Cancer Targeted Drug Delivery

2016 ◽  
Vol 8 (34) ◽  
pp. 22442-22450 ◽  
Author(s):  
Xiaoli Cai ◽  
Yanan Luo ◽  
Weiying Zhang ◽  
Dan Du ◽  
Yuehe Lin
Keyword(s):  
Lung Cancer ◽  
Drug Delivery ◽  
Quantum Dots ◽  
Targeted Drug Delivery ◽  
Ph Sensitive ◽  
Targeted Drug ◽  
Zno Quantum Dots

Ingenious pH-sensitive etoposide loaded folic acid decorated mesoporous silica-carbon dot with carboxymethyl-βcyclodextrin gatekeeper for targeted drug delivery and imaging

2018 ◽  
Vol 92 ◽  
pp. 892-901 ◽  
Author(s):  
Marziyeh Poshteh Shirani ◽  
Behzad Rezaei ◽  
Taghi Khayamian ◽  
Mohammad Dinari ◽  
Fazileh Hosseini Shamili ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Folic Acid ◽  
Mesoporous Silica ◽  
Targeted Drug Delivery ◽  
Ph Sensitive ◽  
Carbon Dot ◽  
Targeted Drug

scholarly journals pH-Sensitive Micelles for Targeted Drug Delivery Prepared Using a Novel Membrane Contactor Method

2013 ◽  
Vol 5 (18) ◽  
pp. 8939-8947 ◽  
Author(s):  
Abdallah Laouini ◽  
Konstantinos P. Koutroumanis ◽  
Catherine Charcosset ◽  
Stella Georgiadou ◽  
Hatem Fessi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Ph Sensitive ◽  
Membrane Contactor ◽  
Targeted Drug

Development of Chitosan-Based pH-Sensitive Polymeric Micelles Containing Curcumin for Colon-Targeted Drug Delivery

2017 ◽  
Vol 19 (3) ◽  
pp. 991-1000 ◽  
Author(s):  
Thisirak Woraphatphadung ◽  
Warayuth Sajomsang ◽  
Theerasak Rojanarata ◽  
Tanasait Ngawhirunpat ◽  
Prasopchai Tonglairoum ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Polymeric Micelles ◽  
Ph Sensitive ◽  
Targeted Drug

pH-Sensitive Nanomedicine for Treating Gynaecological Cancers

2020 ◽  
Vol 2 (2) ◽  
pp. 35-50
Author(s):  
Pramod Vishwanath Prasad ◽  
Kakali Purkayastha ◽  
Utkarsh Sharma ◽  
Mayadhar Barik
Keyword(s):  
Drug Delivery ◽  
Anticancer Agents ◽  
Targeted Drug Delivery ◽  
Drug Carrier ◽  
Therapeutic Index ◽  
Ph Sensitive ◽  
Stimuli Responsive ◽  
Specific Distribution ◽  
Targeted Drug ◽  
Host Tissues

Emergence of various nanoscale drug carrier platforms as Drug Delivery Systems (DDS) has revolutionized the field of medicine.Nonetheless, theside-effects due to non-specific distribution of anticancer therapeutics in normal, healthy tissues remain to be a prime pitfall in curing cancers. Therefore, to achieve a better therapeutic efficacy, the use of a target-specific delivery, combined with a stimuli-responsive nanocarrier system, particularly pH-sensitive nanosystems offer an attractive strategy. Targeted drug delivery through pH-sensitive nanosystems offer the potential to enhance the therapeutic index of anticancer agents, either by increasing the drug concentration in tumor cells and/or by decreasing the exposure in normal host tissues. Therefore, nanoscale-based drug delivery through pH-sensitive nanosystems seem to be a boon for treating gynaecological cancers (as well as other cancers) without side-effects or with least harm to normal healthy tissues.

A pH-sensitive doxorubicin prodrug based on folate-conjugated BSA for tumor-targeted drug delivery

Biomaterials ◽  
2013 ◽  
Vol 34 (12) ◽  
pp. 3087-3097 ◽  
Author(s):  
Changli Du ◽  
Dawei Deng ◽  
Lingling Shan ◽  
Shunan Wan ◽  
Jie Cao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Ph Sensitive ◽  
Targeted Drug
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