scholarly journals Specific detection of CD133-positive tumor cells with iron oxide nanoparticles labeling using noninvasive molecular magnetic resonance imaging

2015 ◽  
pp. 6997 ◽  
Author(s):  
Chen-Pin Chou ◽  
Ya-Wen Chen ◽  
Gunn-Guang Liou ◽  
Huay-Ben Pan ◽  
Hui-Hwa Tseng ◽  
...  
2019 ◽  
Vol 9 (2) ◽  
pp. 166-172
Author(s):  
Ahmed A.G. El-Shahawy ◽  
Gamal Elghnam ◽  
Alsayed A.M. Alsherbini

Background:Gold and Iron Oxide nanoparticles NPs play as nanocarriers for a specific drug delivery and contrast agents. Intercellular uptake of these nanoparticles and targeting to individual cell and sub-cellular compartment is essential.Objective:The aim of the current study is to evaluate the intracellular uptake of these NPs to specific tumor cells in vitro conjugated with folic acid with a goal of enhancing the efficiency of specific targeting to tumor cells.Methods:We synthesized the nanoparticles by a chemical method and characterized by UV-Visible, FTIR, XRD, and TEM.Results & Conclusion:The results revealed the conjugation of Gold and Iron Oxide nanoparticles with folic acid increased the intercellular uptake with high percent compared to non- conjugated nanoparticles.


2008 ◽  
Vol 320 (18) ◽  
pp. 2228-2232 ◽  
Author(s):  
Maxim M. Noginov ◽  
N. Noginova ◽  
O. Amponsah ◽  
R. Bah ◽  
R. Rakhimov ◽  
...  

2011 ◽  
Vol 151 (6) ◽  
pp. 726-730 ◽  
Author(s):  
M. A. Abakumov ◽  
A. E. Goldt ◽  
M. Sokolsky-Papkov ◽  
Y. A. Zorkina ◽  
V. P. Baklaushev ◽  
...  

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