scholarly journals Targeted lung cancer therapy: preparation and optimization of transferrin-decorated nanostructured lipid carriers as novel nanomedicine for co-delivery of anticancer drugs and DNA

2015 ◽  
pp. 1223 ◽  
Author(s):  
Zhenyu Shao ◽  
Jingyu Shao ◽  
Bingxu Tan ◽  
Shanghui Guan ◽  
Zhulong Liu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Anticancer Drugs ◽  
Nanostructured Lipid Carriers ◽  
Lung Cancer Therapy

Tandem Molecular Self-assembly for Selective Lung Cancer Therapy with Two Orders of Magnitude Increase in Efficiency

Nanoscale ◽  
2021 ◽  
Author(s):  
Debin Zheng ◽  
Jingfei Liu ◽  
Yinghao Ding ◽  
Limin Xie ◽  
Yingying Zhang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Anticancer Drugs ◽  
Self Assembly ◽  
Therapeutic Efficacy ◽  
Self Assembling ◽  
Lung Cancer Therapy ◽  
Magnitude Increase

In situ self-assembling of prodrug molecules into nanomedicine can elevate the therapeutic efficacy of anticancer medications by enhancing the targeting and enrichment of anticancer drugs at tumor sites. However, the...

MicroRNAs as Therapeutic Targets for Anticancer Drugs in Lung Cancer Therapy

2020 ◽  
Vol 20 (16) ◽  
pp. 1883-1894
Author(s):  
Yuan-Rong Liu ◽  
Ping-Yu Wang ◽  
Ning Xie ◽  
Shu-Yang Xie
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Anticancer Drugs ◽  
Messenger Rnas ◽  
Antitumor Activities ◽  
Lung Cancers ◽  
Rna Molecules ◽  
Non Coding Rna ◽  
Lung Cancer Therapy ◽  
Therapeutic Mechanisms

MicroRNAs (miRNAs) are short, non-coding RNA molecules that regulate gene expression by translational repression or deregulation of messenger RNAs. Accumulating evidence suggests that miRNAs play various roles in the development and progression of lung cancers. Although their precise roles in targeted cancer therapy are currently unclear, miRNAs have been shown to affect the sensitivity of tumors to anticancer drugs. A large number of recent studies have demonstrated that some anticancer drugs exerted antitumor activities by affecting the expression of miRNAs and their targeted genes. These studies have elucidated the specific biological mechanism of drugs in tumor suppression, which provides a new idea or basis for their clinical application. In this review, we summarized the therapeutic mechanisms of drugs in lung cancer therapy through their effects on miRNAs and their targeted genes, which highlights the roles of miRNAs as targets in lung cancer therapy.

Enhancement of gold-nanocluster-mediated chemotherapeutic efficiency of cisplatin in lung cancer

2021 ◽  
Author(s):  
Mei Jiang ◽  
Yuchen Lin ◽  
Xiaocui Fang ◽  
Mingpeng Liu ◽  
Lilusi Ma ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Delivery System ◽  
Gold Nanoclusters ◽  
Cationic Peptide ◽  
Gold Nanocluster ◽  
Lung Cancer Therapy ◽  
Anti Tumor Activity

A novel delivery system for cisplatin based on electrostatics-mediated assemblies of gold nanoclusters and PEGylated cationic peptide was constructed. The constructed cisplatin@GC-pKs showed much enhanced anti-tumor activity for lung cancer therapy.

Nanomedicine as an emerging platform for metastatic lung cancer therapy

2015 ◽  
Vol 34 (2) ◽  
pp. 291-301 ◽  
Author(s):  
Dalit Landesman-Milo ◽  
Srinivas Ramishetti ◽  
Dan Peer
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Metastatic Lung Cancer ◽  
Metastatic Lung ◽  
Lung Cancer Therapy

scholarly journals Nutlin-3 inhibits the NFκB Pathway in a p53 Dependent Manner: Implications in Lung Cancer Therapy

Cell Cycle ◽  
2007 ◽  
Vol 6 (17) ◽  
pp. 2178-2185 ◽  
Author(s):  
Anwesha Dey ◽  
E.T. Wong ◽  
P. Bist ◽  
V. Tergaonkar ◽  
David Lane
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Dependent Manner ◽  
Lung Cancer Therapy ◽  
Nfκb Pathway

The role of second-generation EGFR inhibitors in lung cancer therapy in the realities of modern clinical practice

2021 ◽  
Vol 10 (4) ◽  
pp. 75
Author(s):  
A.A. Izmailov ◽  
A.F. Nasretdinov ◽  
A.V. Sultanbaev ◽  
D.D. Sakaeva ◽  
K.V. Menshikov ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Clinical Practice ◽  
Cancer Therapy ◽  
Second Generation ◽  
Egfr Inhibitors ◽  
Lung Cancer Therapy
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