scholarly journals Physicochemical and biological properties of a novel injectable polyurethane system for root canal filling

2015 ◽  
pp. 697 ◽  
Author(s):  
Jian Wang ◽  
Yi Zuo ◽  
Minghui Zhao ◽  
Jiaxing Jiang ◽  
Yi Man ◽  
...  
Keyword(s):  
Root Canal ◽  
Biological Properties ◽  
Root Canal Filling ◽  
Physicochemical And Biological Properties

Rational design and fabrication of a β-dicalcium silicate-based multifunctional cement with potential for root canal filling treatment

2014 ◽  
Vol 2 (24) ◽  
pp. 3830-3838 ◽  
Author(s):  
Xianyan Yang ◽  
Min Liu ◽  
Yu Zhao ◽  
Hongyu Jia ◽  
Sanzhong Xu ◽  
...  
Keyword(s):  
Root Canal ◽  
Rational Design ◽  
Biological Properties ◽  
Dicalcium Silicate ◽  
Root Canal Therapy ◽  
Root Canal Filling ◽  
Physicochemical And Biological Properties

Gypsum-introduced, CaO-rich dicalcium silicate-based cements exhibit multifunctional physicochemical and biological properties and meet some challenging criteria in root canal therapy.

scholarly journals Antimicrobial Activity of Two Root Canal Filling Pastes in Deciduous Teeth: an in Vitro Study

2015 ◽  
Vol 17 (1) ◽  
pp. 5
Author(s):  
Andréia Bolzan de Paula ◽  
Janaina De Cássia Orlandi Sardi ◽  
Mariana Minatel ◽  
Regina Maria Puppin-Rontani
Keyword(s):  
Antimicrobial Activity ◽  
Root Canal ◽  
Antimicrobial Property ◽  
Brain Heart Infusion ◽  
In Vitro Study ◽  
Biological Properties ◽  
Deciduous Teeth ◽  
Root Canal Filling ◽  
Agar Diffusion Test

<p>Endodontic treatment in deciduous teeth is very important so that we can preserve the primary dentition and thus promote appropriate craniofacial development. However, the use of filling pastes that have some important biological properties for the preservation of the tooth is required. The objective this study was to evaluate the in vitro antimicrobial activity of two root canal filling pastes in deciduous teeth, Vitapex® and Calcipex®, on microbial species commonly found in endodontic infections (Candida albicans, Enterococcus faecalis, Streptococcus mutans, Streptococcus sanguinis, Escherichia coli and Staphylococcus aureus), using the agar diffusion test. The experiment was carried out on BHI (Brain Heart Infusion) plates in four equidistant points, which were immediately filled with the sealers Vitapex® and Calcipex®. The<br />chlorhexidine gluconate 1% (CHX) and distilled water were used as positive and negative controls, respectively. After incubation of plates at 37 °C for 24 h, the diameter of the growth inhibition zones around the wells was measured (in millimeters) with a digital caliper with reflected light. The test was performed in triplicate and data were submitted to ANOVA and Tukey’s test (α = 0.05). Both pastes had antimicrobial activity, but Calcipex® was more efficient for most strains. The halo formed in the experiments with S. mutans and S. sanguinis was similar for both pastes. This study suggests that Calcipex® had the highest antimicrobial property with respect to the microorganisms studied.</p>

scholarly journals Bioceramics in modern endodontics

2021 ◽  
Vol 19 (3) ◽  
pp. 166-170
Author(s):  
A. V. Mitronin ◽  
D. A. Ostanina ◽  
Yu. A. Mitronin
Keyword(s):  
Clinical Practice ◽  
Clinical Application ◽  
Root Canal ◽  
Calcium Silicate ◽  
Biological Properties ◽  
Review Article ◽  
Endodontic Treatment ◽  
Pulp Therapy ◽  
Vital Pulp Therapy ◽  
Physicochemical And Biological Properties

The introduction of modified bioceramic calcium silicate- based materials into clinical practice has changed the standards and strategies of endodontic treatment. The review article highlights modern calcium silicate- based cements that are used in various areas of endodontics, including vital pulp therapy, root canal obturation, management of endodontic complications and pulp regeneration. The classifications of bioceramic materials based on their chemistry and specific use in endodontics are presented. The physicochemical and biological properties of various types of materials, as well as the features of their clinical application, are described.

In-Vitro Comparison of Antibacterial Effect of Epoxic Resin and Tricalcium Silicate Based Cements

2021 ◽  
Author(s):  
Rosa Isela Álvarez Reyes
Keyword(s):  
Bacterial Growth ◽  
Root Canal ◽  
Biological Properties ◽  
Root Canal Therapy ◽  
Root Canal Filling ◽  
Mueller Hinton ◽  
Mueller Hinton Agar ◽  
Ah Plus ◽  
Endodontic Sealers

Introduction: Root Canal Filling is the final procedure during root canal therapy, where endodontic sealers should have physical, chemical, and biological properties that help to reduce the population of residual bacteria and create a favorable environment for the repair of periapical tissues. The aim of this work was to compare the antibacterial capacity of AH Plus (Denstply®) and BioRoot RCS (Septodont®). Materials and Methods: Negative-Coagulase Streptococcus, Streptococcus salivarius, and Enterococcus faecalis were isolated from a necrotic pulp. They were tested by Minimum Inhibitory Concentration (MIC): 50 µl of saline solution and 100 µl of AH Plus and BioRoot RCS were used to perform the following dilutions of 1:2, 1:4, 1:8, 1:16, 1:32, 1:64, 1:128, 1:256, 1:512, 1:1024. Subsequently, the samples were cultured on Müeller- Hinton agar with sheep blood, to assess bacterial growth. Results: AH Plus showed growth up to 1:64 dilution and BIOROOT = 1:32 in E. faecalis while in Negative-Coagulase Streptococcus both cements showed growth at 1:2048 dilution, in S. salivarius there was no bacterial growth with both cements. Conclusion: AH plus (Denstply®) and BioRoot RCS RCS (Septodont®) are cements that provided an effective bacterial activity in isolated microorganisms: E. faecalis, S. Coagulase Negative and S. salivarius.

Scanning Electron Microscope Study of Root Canal Filling (First Report)

1987 ◽  
Vol 41 (6) ◽  
pp. 1238-1243
Author(s):  
Yohichiroh Soh ◽  
Junroh Tahara ◽  
Takashi Hayashikawa ◽  
Masatoshi Hitaka ◽  
Kohzoh Kubota ◽  
...  
Keyword(s):  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Root Canal ◽  
Microscope Study ◽  
Electron Microscope Study ◽  
Root Canal Filling ◽  
Scanning Electron Microscope Study ◽  
First Report ◽  
Scanning Electron

scholarly journals The Influence of Bloom Index, Endotoxin Levels and Polyethylene Glycol Succinimidyl Glutarate Crosslinking on the Physicochemical and Biological Properties of Gelatin Biomaterials

Biomolecules ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1003
Author(s):  
Zhuning Wu ◽  
Stefanie H. Korntner ◽  
Jos Olijve ◽  
Anne Maria Mullen ◽  
Dimitios I. Zeugolis
Keyword(s):  
Elastic Modulus ◽  
Polyethylene Glycol ◽  
Enzymatic Degradation ◽  
Structural Integrity ◽  
Biological Response ◽  
Biological Properties ◽  
Compression Stress ◽  
Free Amine ◽  
Amine Content ◽  
Physicochemical And Biological Properties

In the medical device sector, bloom index and residual endotoxins should be controlled, as they are crucial regulators of the device’s physicochemical and biological properties. It is also imperative to identify a suitable crosslinking method to increase mechanical integrity, without jeopardising cellular functions of gelatin-based devices. Herein, gelatin preparations with variable bloom index and endotoxin levels were used to fabricate non-crosslinked and polyethylene glycol succinimidyl glutarate crosslinked gelatin scaffolds, the physicochemical and biological properties of which were subsequently assessed. Gelatin preparations with low bloom index resulted in hydrogels with significantly (p < 0.05) lower compression stress, elastic modulus and resistance to enzymatic degradation, and significantly higher (p < 0.05) free amine content than gelatin preparations with high bloom index. Gelatin preparations with high endotoxin levels resulted in films that induced significantly (p < 0.05) higher macrophage clusters than gelatin preparations with low endotoxin level. Our data suggest that the bloom index modulates the physicochemical properties, and the endotoxin content regulates the biological response of gelatin biomaterials. Although polyethylene glycol succinimidyl glutarate crosslinking significantly (p < 0.05) increased compression stress, elastic modulus and resistance to enzymatic degradation, and significantly (p < 0.05) decreased free amine content, at the concentration used, it did not provide sufficient structural integrity to support cell culture. Therefore, the quest for the optimal gelatin crosslinker continues.

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