scholarly journals Enhanced and selective delivery of enzyme therapy to 9L-glioma tumor via magnetic targeting of PEG-modified, ß-glucosidase- conjugated iron oxide nanoparticles

2014 ◽  
pp. 2905 ◽  
Author(s):  
Jie Zhou ◽  
Jian Zhang ◽  
Wenxi Gao
2017 ◽  
Vol 6 (5) ◽  
pp. 449-472 ◽  
Author(s):  
Marina Fontes de Paula Aguiar ◽  
Javier Bustamante Mamani ◽  
Taylla Klei Felix ◽  
Rafael Ferreira dos Reis ◽  
Helio Rodrigues da Silva ◽  
...  

AbstractThe purpose of this study was to review the use of the magnetic targeting technique, characterized by magnetic driving compounds based on superparamagnetic iron oxide nanoparticles (SPIONs), as drug delivery for a specific brain locus in gliomas. We reviewed a process mediated by the application of an external static magnetic field for targeting SPIONs in gliomas. A search of PubMed, Cochrane Library, Scopus, and Web of Science databases identified 228 studies, 23 of which were selected based on inclusion criteria and predetermined exclusion criteria. The articles were analyzed by physicochemical characteristics of SPIONs used, cell types used for tumor induction, characteristics of experimental glioma models, magnetic targeting technical parameters, and analysis method of process efficiency. The study shows the highlights and importance of magnetic targeting to optimize the magnetic targeting process as a therapeutic strategy for gliomas. Regardless of the intensity of the patterned magnetic field, the time of application of the field, and nanoparticle used (commercial or synthesized), all studies showed a vast advantage in the use of magnetic targeting, either alone or in combination with other techniques, for optimized glioma therapy. Therefore, this review elucidates the preclinical and therapeutic applications of magnetic targeting in glioma, an innovative nanobiotechnological method.


nano Online ◽  
2018 ◽  
Author(s):  
Marina Fontes de Paula Aguiar ◽  
Javier Bustamante Mamani ◽  
Taylla Klei Felix ◽  
Rafael Ferreira dos Reis ◽  
Helio Rodrigues da Silva ◽  
...  

Biomaterials ◽  
2008 ◽  
Vol 29 (4) ◽  
pp. 487-496 ◽  
Author(s):  
Beata Chertok ◽  
Bradford A. Moffat ◽  
Allan E. David ◽  
Faquan Yu ◽  
Christian Bergemann ◽  
...  

2019 ◽  
Vol 194 (2) ◽  
pp. 502-513 ◽  
Author(s):  
Maria Fernanda Hornos Carneiro ◽  
Ana Rita T. Machado ◽  
Lusânia M. G. Antunes ◽  
Talita E. Souza ◽  
Victor A. Freitas ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (57) ◽  
pp. 36319-36328
Author(s):  
Mehnaz Rashid ◽  
Md. Ahasanur Rabbi ◽  
Tabassum Ara ◽  
Md. Motahar Hossain ◽  
Md. Shahidul Islam ◽  
...  

(a) The separation of bacteria by vancomycin conjugated Fe3O4/DOPA/Van nanoparticles and (b) H-bonding interactions between the vancomycin molecule and the d-alanyl-d-alanine dipeptide of the bacterial surface.


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