scholarly journals Gene expression profiles in primary duodenal chick cells following transfection with avian influenza virus H5 DNA plasmid encapsulated in silver nanoparticles

2013 ◽  
pp. 781 ◽  
Author(s):  
Seyed Davoud Jazayeri ◽  
Aini Ideris ◽  
Kamyar Shameli ◽  
Moeini ◽  
Abdul Rahman Omar
Keyword(s):  
Gene Expression ◽  
Silver Nanoparticles ◽  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Dna Plasmid

Silver nanoparticles coated graphene electrochemical sensor for the ultrasensitive analysis of avian influenza virus H7

2016 ◽  
Vol 913 ◽  
pp. 121-127 ◽  
Author(s):  
Jiaoling Huang ◽  
Zhixun Xie ◽  
Zhiqin Xie ◽  
Sisi Luo ◽  
Liji Xie ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Influenza Virus ◽  
Avian Influenza ◽  
Electrochemical Sensor ◽  
Avian Influenza Virus

scholarly journals Analysis of the microRNA expression profiles of chicken dendritic cells in response to H9N2 avian influenza virus infection

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Jing Yang ◽  
Xinmei Huang ◽  
Yuzhuo Liu ◽  
Dongmin Zhao ◽  
Kaikai Han ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Expression Profiles ◽  
Influenza Virus Infection ◽  
H9n2 Avian Influenza Virus ◽  
Host Interactions ◽  
Deep Sequencing Technology ◽  
Host Defense Response

Abstract MicroRNA (miRNA) plays a key role in virus-host interactions. Here, we employed deep sequencing technology to determine cellular miRNA expression profiles in chicken dendritic cells infected with H9N2 avian influenza virus (AIV). A total of 66 known and 36 novel miRNAs were differently expressed upon H9N2 infection, including 72 up-regulated and 30 down-regulated miRNAs. Functional analysis showed that the predicted targets of these miRNAs were significantly enriched in several pathways including endocytosis, notch, lysosome, p53, RIG-I-like and NOD-like receptor signaling pathways. These data provide valuable information for further investigating the roles of miRNA in AIV pathogenesis and host defense response.

scholarly journals MicroRNA expression profiles from HEK293 cells expressing H5N1 avian influenza virus non-structural protein 1

2019 ◽  
Vol 25 (2) ◽  
pp. 110-117 ◽  
Author(s):  
Hanwei Jiao ◽  
Zonglin Zheng ◽  
Xuehong Shuai ◽  
Li Wu ◽  
Jixuan Chen ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Target Genes ◽  
Expression Profiles ◽  
Differentially Expressed ◽  
Hek293 Cells ◽  
Illumina Genome Analyzer ◽  
Structural Protein ◽  
H5n1 Avian Influenza

H5N1 avian influenza poses a serious threat to the poultry industry and human health. Non-structural protein 1 (NS1) plays an important role in the replication and pathogenesis of avian influenza virus (AIV). However, the function of the NS1 gene is still unclear. In this study, illumina genome analyzer iix screening was used to identify the differentially expressed microRNAs (miRNAs) in HEK293 cells expressing H5N1 AIV NS1. There were 13 differentially expressed miRNAs (hsa-miR-17-5p, hsa-miR-221-3p, hsa-miR-22-3p, hsa-miR-31-5p, hsa-miR-20a-5p, hsa-miR-222-3p, hsa-miR-24-3p, hsa-miR-3613-3p, hsa-miR-3178, hsa-miR-4505, hsa-miR-345-3p, hsa-miR-3648, and hsa-miR-455-3p) ( P < 0.01). The qRT-PCR validation results demonstrated that hsa-miR-221-3p, hsa-miR-22-3p, hsa-miR-20a-5p, and hsa-miR-3613-3p were upregulated, while hsa-miR-3178 and hsa-miR-4505 were down-regulated. The softwares targetscan and miranda were further used to predict their target genes, and the gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis results showed that 20 GO terms and 20 KEGG pathways were significantly enriched. Our findings are the first to report expression profiling of miRNA and their functions in H5N1 AIV NS1-expressing HEK293 cells, and pave the way to further elucidating the accurate interaction mechanism between NS1 and virus replication, thus providing brand new insight into the prophylaxis and treatment of H5N1 AIV.

scholarly journals Erratum: Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Su-Jin Park ◽  
Mukesh Kumar ◽  
Hyeok-il Kwon ◽  
Rak-Kyun Seong ◽  
Kyudong Han ◽  
...  
Keyword(s):  
Gene Expression ◽  
Influenza Virus ◽  
Virus Infection ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Influenza Virus Infection ◽  
Host Gene ◽  
Host Gene Expression ◽  
Dynamic Changes
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