scholarly journals New Peceol™/Span™ 60 Niosomes Coated with Chitosan for Candesartan Cilexetil: Perspective Increase in Absolute Bioavailability in Rats

2021 ◽  
Vol Volume 16 ◽  
pp. 5581-5601
Author(s):  
Aya Mohamed AbuElfadl ◽  
Mariza Boughdady ◽  
Mahasen Meshali
Keyword(s):  
Candesartan Cilexetil ◽  
Absolute Bioavailability

The use of isotopes in the determination of absolute bioavailability of drugs in humans

2006 ◽  
Vol 2 (3) ◽  
pp. 419-427 ◽  
Author(s):  
Graham Lappin ◽  
Malcolm Rowland ◽  
R Colin Garner
Keyword(s):  
Absolute Bioavailability

scholarly journals Oral Bioavailability and Pharmacokinetics of Trovafloxacin in Patients with AIDS

1999 ◽  
Vol 43 (12) ◽  
pp. 3005-3007 ◽  
Author(s):  
Melinda K. Lacy ◽  
David P. Nicolau ◽  
Charles H. Nightingale ◽  
Amy Geffken ◽  
Renli Teng ◽  
...  
Keyword(s):  
Oral Bioavailability ◽  
Active Form ◽  
Healthy Adults ◽  
Absolute Bioavailability ◽  
Randomized Design ◽  
The Mean

ABSTRACT Trovafloxacin pharmacokinetics were evaluated in 12 subjects with AIDS. By using a randomized design, single 200-mg doses of oral trovafloxacin and intravenous alatrofloxacin were administered. The mean absolute bioavailability was 91%. The pharmacokinetics of trovafloxacin when administered orally as the active form or intravenously as the prodrug (alatrofloxacin) are not altered in subjects with AIDS compared to those in healthy adults.

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