scholarly journals Co-Administration of iRGD with Sorafenib-Loaded Iron-Based Metal-Organic Framework as a Targeted Ferroptosis Agent for Liver Cancer Therapy

2021 ◽  
Vol Volume 16 ◽  
pp. 1037-1050
Author(s):  
Xianchuang Liu ◽  
Xinyang Zhu ◽  
Xun Qi ◽  
Xianwei Meng ◽  
Ke Xu
Keyword(s):  
Cancer Therapy ◽  
Liver Cancer ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Iron Based ◽  
Organic Framework

Multifunctional metal–organic framework heterostructures for enhanced cancer therapy

2021 ◽  
Author(s):  
Jintong Liu ◽  
Jing Huang ◽  
Lei Zhang ◽  
Jianping Lei
Keyword(s):  
Cancer Therapy ◽  
General Principle ◽  
Biomedical Applications ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Functional Modulation ◽  
Organic Framework

We review the general principle of the design and functional modulation of nanoscaled MOF heterostructures, and biomedical applications in enhanced therapy.

Recent advances in the development of metal-organic framework-based gas nanoplatforms for synergistic cancer therapy

2021 ◽  
Author(s):  
Yong Yao ◽  
Danni Jing ◽  
Jianan Zhang ◽  
Youyou Huang ◽  
Xiru Qin ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Therapeutic Efficacy ◽  
Metal Organic Framework ◽  
Research Field ◽  
Tumor Site ◽  
Recent Advances ◽  
Metal Organic ◽  
Organic Framework

Featuring high therapeutic efficacy, biocompatibility, and biosafety, gas therapy as a burgeoning and promising research field has attracted considerable attention in biomedicine. However, the lack of the tumor site accumulation...

Metal-organic framework IRMOFs coated with a temperature-sensitive gel delivering norcantharidin to treat liver cancer

2021 ◽  
Vol 27 (26) ◽  
pp. 4203-4215
Author(s):  
Xiu-Yan Li ◽  
Qing-Xia Guan ◽  
Yu-Zhou Shang ◽  
Yan-Hong Wang ◽  
Shao-Wa Lv ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Metal Organic Framework ◽  
Temperature Sensitive ◽  
Metal Organic ◽  
Organic Framework

Iron-Decorated, Guanidine Functionalized Metal-Organic Framework as a Non-heme Iron-Based Enzyme Mimic System for Catalytic Oxidation of Organic Substrates

2019 ◽  
Vol 149 (5) ◽  
pp. 1237-1249 ◽  
Author(s):  
Ahmad Shaabani ◽  
Reza Mohammadian ◽  
Hassan Farhid ◽  
Masoumeh Karimi Alavijeh ◽  
Mostafa M. Amini
Keyword(s):  
Catalytic Oxidation ◽  
Metal Organic Framework ◽  
Enzyme Mimic ◽  
Heme Iron ◽  
Organic Substrates ◽  
Non Heme Iron ◽  
Metal Organic ◽  
Iron Based ◽  
Organic Framework

scholarly journals Mechanochemical Approaches Towards the in Situ Confinement of 5-FU Anti-Cancer Drug Within MIL-100 (Fe) Metal-Organic Framework

2020 ◽  
Author(s):  
Barbara Souza ◽  
Jin-Chong Tan
Keyword(s):  
Drug Release ◽  
Metal Organic Framework ◽  
Cancer Drug ◽  
One Pot ◽  
Host Interactions ◽  
Anti Cancer ◽  
Metal Organic ◽  
Iron Based ◽  
Organic Framework

We report two solvent-free mechanochemical methods to achieve one‑pot encapsulation of anti-cancer drug 5‑Fluorouracil (5‑FU) in the iron-based MIL‑100 metal-organic framework (MOF). We compare the structural and physicochemical properties of drug@MIL‑100 systems derived from <i>in situ </i>manual and vortex grinding, where the former exhibits a slower drug release due to stronger guest-host interactions.

scholarly journals A Singlet Oxygen Reservoir Based on Poly-Pyridone and Porphyrin Nanoscale Metal–Organic Framework for Cancer Therapy

CCS Chemistry ◽  
2020 ◽  
pp. 1187-1202
Author(s):  
Bo-Ru Xie ◽  
Chu-Xin Li ◽  
Yun Yu ◽  
Jin-Yue Zeng ◽  
Ming-Kang Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Metal Organic Framework ◽  
Metal Organic ◽  
Organic Framework
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