scholarly journals Carbon Dots from Paeoniae Radix Alba Carbonisata: Hepatoprotective Effect

2020 ◽  
Vol Volume 15 ◽  
pp. 9049-9059
Author(s):  
Yusheng Zhao ◽  
Yue Zhang ◽  
Hui Kong ◽  
Meiling Zhang ◽  
Jinjun Cheng ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Hepatoprotective Effect ◽  
Paeoniae Radix

scholarly journals Hepatoprotective effect of Paeoniae radix via Nrf2 activation

2016 ◽  
Vol 31 (1) ◽  
pp. 33-40 ◽  
Author(s):  
Soo Hwan Lee ◽  
Ji Yun Jung ◽  
Sang Mi Park ◽  
Kyung Hwan Jegal ◽  
Sung Hui Byun ◽  
...  
Keyword(s):  
Hepatoprotective Effect ◽  
Nrf2 Activation ◽  
Paeoniae Radix

Screening of traditional Saudi plants for hepatoprotective effect

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
SI Alqasoumi ◽  
MS Abdel-Kader
Keyword(s):  
Hepatoprotective Effect

Hepatoprotective Effect of Curdrania tricuspidata Extracts against Oxidative Damage

2012 ◽  
Vol 41 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Ok-Kyung Kim ◽  
Jin-Nyoung Ho ◽  
Da-Eun Nam ◽  
Woo-Jin Jun ◽  
Kwon-Tack Hwang ◽  
...  
Keyword(s):  
Oxidative Damage ◽  
Hepatoprotective Effect

Heteroatom Doped Carbon Dots with Nanoenzyme Like Properties as Theranostic Platforms for Free Radical Scavenging, Imaging, and Chemotherapy

2020 ◽  
Author(s):  
Khalilalrahman Dehvari ◽  
Sheng-Hui Chiu ◽  
Jin-Sheng Lin ◽  
Wubshet Mekonnen Girm ◽  
Yong-Chien Ling ◽  
...  
Keyword(s):  
Free Radical ◽  
Carbon Dots ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Doped Carbon Dots

Carbon Dots for Bacterial Detection and Antibacterial Applications-A Minireview

2020 ◽  
Vol 25 (46) ◽  
pp. 4848-4860 ◽  
Author(s):  
Anisha Anand ◽  
Gopinathan Manavalan ◽  
Ranju Prasad Mandal ◽  
Huan-Tsung Chang ◽  
Yi-Ru Chiou ◽  
...  
Keyword(s):  
Optical Properties ◽  
Carbon Dots ◽  
Antibacterial Effect ◽  
Bacterial Detection ◽  
High Brightness ◽  
Photo Catalysis ◽  
Wide Range ◽  
Prevention And Treatment ◽  
Low Toxicity ◽  
Conventional Antibiotics

: The prevention and treatment of various infections caused by microbes through antibiotics are becoming less effective due to antimicrobial resistance. Researches are focused on antimicrobial nanomaterials to inhibit bacterial growth and destroy the cells, to replace conventional antibiotics. Recently, carbon dots (C-Dots) become attractive candidates for a wide range of applications, including the detection and treatment of pathogens. In addition to low toxicity, ease of synthesis and functionalization, and high biocompatibility, C-Dots show excellent optical properties such as multi-emission, high brightness, and photostability. C-Dots have shown great potential in various fields, such as biosensing, nanomedicine, photo-catalysis, and bioimaging. This review focuses on the origin and synthesis of various C-Dots with special emphasis on bacterial detection, the antibacterial effect of CDots, and their mechanism.

Nitrogen and Sulfur Co-doped Fluorescent Carbon Dots for the Detection of Morin and Cell Imaging

2018 ◽  
Vol 15 (1) ◽  
pp. 47-55
Author(s):  
Xuebing Li ◽  
Haifen Yang ◽  
Ning Wang ◽  
Tijian Sun ◽  
Wei Bian ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Fluorescent Probe ◽  
Fluorescence Intensity ◽  
Carbon Dots ◽  
Cell Imaging ◽  
Water Soluble ◽  
Heating Process ◽  
X Ray ◽  
Doped Carbon Dots ◽  
Co Doped

Background: Morin has many pharmacological functions including antioxidant, anticancer, anti-inflammatory, and antibacterial effects. It is commonly used in the treatment of antiviral infection, gastropathy, coronary heart disease and hepatitis B in clinic. However, researches have shown that morin is likely to show prooxidative effects on the cells when the amount of treatment is at high dose, leading to the decrease of intracellular ATP levels and the increase of necrosis process. Therefore, it is necessary to determine the concentration of morin in biologic samples. Method: Novel water-soluble and green nitrogen and sulfur co-doped carbon dots (NSCDs) were prepared by a microwave heating process with citric acid and L-cysteine. The fluorescence spectra were collected at an excitation wavelength of 350 nm when solutions of NSCDs were mixed with various concentrations of morin. Results: The as-prepared NSCDs were characterized by transmission electron microscopy, X-ray diffraction and X-ray photoelectron spectroscopy. The fluorescence intensity of NSCDs decreased significantly with the increase of morin concentration. The fluorescence intensity of NSCDs displayed a linear response to morin in the concentration 0.10-30 μM with a low detection limit of 56 nM. The proposed fluorescent probe was applied to analysis of morin in human body fluids with recoveries of 98.0-102%. Conclusion: NSCDs were prepared by a microwave heating process. The present analytical method is sensitive to morin. The quenching process between NSCDs and morin is attributed to the static quenching. In addition, the cellular toxicity on HeLa cells indicated that the as-prepared NSCDs fluorescent probe does not show obvious cytotoxicity in cell imaging. Our proposed method possibly opens up a rapid and nontoxic way for preparing heteroatom doped carbon dots with a broad application prospect.

Nitrogen-doped carbon dots from Hutai-8 grape skin and their application in Hg2+ detection

2020 ◽  
Vol 16 ◽  
Author(s):  
Pan Zhang ◽  
Shun-Sheng Zhao ◽  
JiaJia Wang ◽  
Xiang Rong Liu
Keyword(s):  
Heavy Metal ◽  
Carbon Source ◽  
Fluorescence Quenching ◽  
Hydrothermal Method ◽  
Water Samples ◽  
Carbon Dots ◽  
Mercury Ions ◽  
Grape Skin ◽  
Fluorescent Carbon Dots ◽  
Fluorescent Carbon

Background: In recent years, environmental pollution and heavy metal pollution caused by rapid urbanization and industrialization have become increasingly serious. Among them, mercury (II) ion (Hg2+) is one of the highly toxic heavy metal ions, and its pollution comes from various natural resources and human activities. Therefore, people attach great importance to the development of analytical methods for effective analysis and sensitive detection of Hg2+ . Objective: Using grape skin as a green and environmental friendly carbon source, to synthesize fluorescent carbon dots, and try to apply them to the detect the concentration of Hg2+ in water. Method: Using "Hutai No. 8" grape skin as carbon source, fluorescent carbon dots were synthesized by one-step hydrothermal method. Structure and fluorescent properties of the carbon dots were tested using TEM, XPS, XRD and other characterization instruments, and their utilization on detection of mercury ions in the actual water samples was explored. Results: The CDs had a particle size of about 4.8 nm and a spherical shape. There are N-H, C-N, C=O and other functional groups on the surface. It was found that Hg2+ has obvious fluorescence quenching effect on CDs, and thus CDs fluorescence quenching method to detect the concentration Hg2+ was established, and the detection limit is 3.7 μM, which could be applied to test the concentration of Hg2+ in water samples. Conclusion: Using grape skin as carbon source, fluorescent carbon dots were successfully synthesized by hydrothermal method. Carbon dots were used to detect mercury ions in water, and a method for detecting mercury ions in actual water samples was established.

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