scholarly journals Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptake

2011 ◽  
pp. 3151 ◽  
Author(s):  
Yong Gan ◽  
Xiuying Li ◽  
Dan Chen ◽  
Chaoyi Le ◽  
Chunliu Zhu ◽  
...  
Author(s):  
Ranajit Nath ◽  
Ratul Bhowmik ◽  
Rajarshi Chakraborty ◽  
Sourav Datta ◽  
Apala Chakraborty

Diltiazem, a calcium ion cellular influx inhibitor is known for its limited and variable bioavailability. This study is intended to explore the benefits of microemulsion formulation as an oral drug delivery system for immediate release to improve the bioavailability and efficacy of Diltiazem. Methods: Oil in water microemulsion was prepared using the simple water titration method. The optimized formulation was evaluated for physicochemical parameters like viscosity, pH, conductivity, and accelerated stability studies. In vitro release, diltiazem microemulsion was investigated.


2012 ◽  
Vol 9 (2) ◽  
pp. 213-217 ◽  
Author(s):  
Mehdi Rahimi ◽  
Hamid Mobedi ◽  
Aliasghar Behnamghader ◽  
Alireza Nateghi Baygi ◽  
Houri Mivehchi ◽  
...  

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