scholarly journals Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response

2020 ◽  
Vol Volume 15 ◽  
pp. 1499-1515 ◽  
Author(s):  
Peidi Yin ◽  
Huifeng Li ◽  
Chao Ke ◽  
Guangxu Cao ◽  
Xiaoqian Xin ◽  
...  
Keyword(s):  
Immune Response ◽  
Intranasal Delivery ◽  
In Situ Activation

scholarly journals Intranasal Delivery of Immunotherapeutic Nanoformulations for Treatment of Glioma Through in situ Activation of Immune Response [Corrigendum]

2020 ◽  
Vol Volume 15 ◽  
pp. 8873-8874
Author(s):  
Peidi Yin ◽  
Huifeng Li ◽  
Chao Ke ◽  
Guangxu Cao ◽  
Xiaoqian Xin ◽  
...  
Keyword(s):  
Immune Response ◽  
Intranasal Delivery ◽  
In Situ Activation

A Photoactivatable α5β1-Specific Integrin Ligand

2018 ◽  
Author(s):  
Roshna Vakkeel ◽  
Aleeza Farrukh ◽  
Aranzazu del Campo
Keyword(s):  
Cellular Response ◽  
Light Exposure ◽  
Matrix Composition ◽  
Cellular Behavior ◽  
Dynamic Variations ◽  
In Situ Activation ◽  
Controlled Exposure ◽  
Cellular Behaviour ◽  
Integrin Ligand

In order to study how dynamic changes of α5β1 integrin engagement affect cellular behaviour, photoactivatable derivatives of α5β1 specific ligands are presented in this article. The presence of the photoremovable protecting group (PRPG) introduced at a relevant position for integrin recognition, temporally inhibits ligand bioactivity. Light exposure at cell-compatible dose efficiently cleaves the PRPG and restores functionality. Selective cell response (attachment, spreading, migration) to the activated ligand on the surface is achieved upon controlled exposure. Spatial and temporal control of the cellular response is demonstrated, including the possibility to in situ activation. Photoactivatable integrin-selective ligands in model microenvironments will allow the study of cellular behavior in response to changes in the activation of individual integrins as consequence of dynamic variations of matrix composition.

Comparative study of MoS2 and Co/MoS2 catalysts prepared by ex situ/in situ activation of ammonium and tetraalkylammonium thiomolybdates

2004 ◽  
Vol 210 (1-2) ◽  
pp. 105-117 ◽  
Author(s):  
L. Alvarez ◽  
J. Espino ◽  
C. Ornelas ◽  
J.L. Rico ◽  
M.T. Cortez ◽  
...  
Keyword(s):  
Comparative Study ◽  
Ex Situ ◽  
In Situ Activation ◽  
Mos2 Catalysts

Efficient Transamidation of Primary Carboxamides by in Situ Activation withN,N-Dialkylformamide Dimethyl Acetals

2006 ◽  
Vol 128 (50) ◽  
pp. 16406-16409 ◽  
Author(s):  
Thomas A. Dineen ◽  
Matthew A. Zajac ◽  
Andrew G. Myers
Keyword(s):  
In Situ Activation

In situ activation of T-lymphocytes in chronic viral and autoimmune hepatitis

1989 ◽  
Vol 9 ◽  
pp. S144
Author(s):  
H.P. Dienes ◽  
F. Autschbach ◽  
M. Wörsdörfer ◽  
S.C. Meuer ◽  
M. Manns ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Autoimmune Hepatitis ◽  
In Situ Activation
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