scholarly journals Docetaxel immunonanocarriers as targeted delivery systems for HER2-positive tumor cells: preparation, characterization, and cytotoxicity studies

2011 ◽  
pp. 1903 ◽  
Author(s):  
Rassoul Dinarvand ◽  
Mona Noori Koopaei ◽  
Amini ◽  
Rabbani ◽  
Ostad ◽  
...  
2016 ◽  
Vol 17 (3) ◽  
pp. 428 ◽  
Author(s):  
Lei Dang ◽  
Jin Liu ◽  
Fangfei Li ◽  
Luyao Wang ◽  
Defang Li ◽  
...  

2020 ◽  
Vol 69 (4) ◽  
pp. 793-803
Author(s):  
M. B. Sokol ◽  
M. R. Faustova ◽  
E. D. Nikolskaya ◽  
O. A. Zhunina ◽  
M. V. Fomicheva ◽  
...  

Technologies ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 71
Author(s):  
Petr Snetkov ◽  
Kseniia Zakharova ◽  
Svetlana Morozkina ◽  
Mikhail Baranov ◽  
Roman Olekhnovich ◽  
...  

Modern drug delivery systems demand the development of targeted polymer-carriers with the set of obligatory requirements. Thus, such capsules must have total biocompatibility, biodegradability, and possess non-allergenic, and non-tumorigenic properties. Hyaluronic acid (HA), as a natural linear polysaccharide that is included in the pericellular and extracellular matrixes, satisfies all these demands in the best possible way. In this study, the biopolymer nanoparticles with an average diameter of 300 nm were successfully obtained from aqueous HA solutions by electrospraying technique and characterized. Due to the presence of active functional groups in the structure of HA, such polymer particles can incorporate various pharmaceutical agents. This finding expands the investigation and subsequent application of drug-loaded nanoparticles based on HA as challenging and advanced targeted delivery systems.


Author(s):  
Marina A. Dumpis ◽  
Marija A. Brusina ◽  
Elena V. Litasova ◽  
Viktor V. Iljin ◽  
Dmitrii N. Nikolayev ◽  
...  

The review discusses in detail the causes of side effects of drugs, caused, inter alia, by the high complexity of the organism. The different ways are represented to overcome this problem by creating, in particular, targeted delivery systems. But nevertheless, drugs whose activity is manifested in milligram doses have minimal side effects.


2020 ◽  
Vol 18 (4) ◽  
pp. 313-326
Author(s):  
Marina A. Dumpis ◽  
Marija A. Brusina ◽  
Elena V. Litasova ◽  
Viktor V. Iljin ◽  
Dmitrii N. Nikolayev ◽  
...  

The review discusses in detail the causes of side effects of drugs, caused, inter alia, by the high complexity of the organism. The different ways are represented to overcome this problem by creating, in particular, targeted delivery systems. But nevertheless, drugs whose activity is manifested in milligram doses have minimal side effects.


Sign in / Sign up

Export Citation Format

Share Document