scholarly journals Improvement of Paclitaxel-Associated Adverse Reactions (ADRs) via the Use of Nano-Based Drug Delivery Systems: A Systematic Review and Network Meta-Analysis

2020 ◽  
Vol Volume 15 ◽  
pp. 1731-1743 ◽  
Author(s):  
Pi-Ling Chou ◽  
Ya-Ping Huang ◽  
Meng-Hsuan Cheng ◽  
Kun-Ming Rau ◽  
Yi-Ping Fang
Keyword(s):  
Systematic Review ◽  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Adverse Reactions ◽  
Meta Analysis ◽  
Delivery Systems

scholarly journals RECENT APPROACHES INVOLVED IN COLONIC DRUG TARGETING FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE: A REVIEW

2021 ◽  
pp. 40-46
Author(s):  
SWAMINATHAN V. ◽  
VAIYANA RAJESH C.
Keyword(s):  
Drug Delivery ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Drug Targeting ◽  
Drug Delivery Systems ◽  
Adverse Reactions ◽  
Delivery Systems ◽  
Systemic Absorption ◽  
Conventional Drug ◽  
Inflammatory Bowel

The objective of the review is to present the contemporary approaches involved in colonic drug targeting for the therapy of inflammatory bowel disease (IBD). The adverse reactions and side-effects of the conventional drug delivery systems are largely on account of the systemic absorption of the drugs from the small intestine. Moreover, in current drug delivery systems, the drug has to be frequently administered and also in larger doses which greatly reduces patient compliance. Various approaches which are being described here mainly target the colonic region specifically for improved therapy of IBD, by increasing localization and accessibility of the drug to the target site. Also, these approaches will result in the reduction of dose and minimization of adverse effects combined with the use of conventional drug delivery systems.

scholarly journals Cytotoxicity of targeted PLGA nanoparticles: a systematic review

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9433-9449
Author(s):  
Hock Ing Chiu ◽  
Nozlena Abdul Samad ◽  
Lizhen Fang ◽  
Vuanghao Lim
Keyword(s):  
Systematic Review ◽  
Drug Delivery ◽  
Targeted Drug Delivery ◽  
Drug Delivery Systems ◽  
Plga Nanoparticles ◽  
Delivery Systems ◽  
Normal Cells ◽  
Anti Cancer ◽  
Targeted Drug ◽  
Targeted Drug Delivery Systems

Targeted drug delivery systems using PLGA as a nanocarrier for anti-cancer agents to improve efficacy and reduce toxicity in normal cells.

Sign in / Sign up

Export Citation Format

Share Document