scholarly journals Ameliorative Effect Of Zinc Oxide Nanoparticles Against Dermal Toxicity Induced By Lead Oxide In Rats

2019 ◽  
Vol Volume 14 ◽  
pp. 7729-7741 ◽  
Author(s):  
AA Khalaf ◽  
Eman I. Hassanen ◽  
Rehab A. Azouz ◽  
Amr R. Zaki ◽  
Marwa A. Ibrahim ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Lead Oxide ◽  
Oxide Nanoparticles ◽  
Dermal Toxicity ◽  
Ameliorative Effect

In vivo toxicity of copper oxide, lead oxide and zinc oxide nanoparticles acting in different combinations and its attenuation with a complex of innocuous bio-protectors

Toxicology ◽  
2017 ◽  
Vol 380 ◽  
pp. 72-93 ◽  
Author(s):  
Ilzira A. Minigalieva ◽  
Boris A. Katsnelson ◽  
Vladimir G. Panov ◽  
Larisa I. Privalova ◽  
Anatoly N. Varaksin ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Copper Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Lead Oxide ◽  
Oxide Nanoparticles ◽  
In Vivo Toxicity

scholarly journals Zinc oxide nanoparticles: a 90-day repeated-dose dermal toxicity study in rats

2014 ◽  
pp. 137 ◽  
Author(s):  
Seong Soo A. An ◽  
Hwa Jung Ryu ◽  
Mu yeb Seo ◽  
Sung Kyu Jung ◽  
Eun-Ho Meang ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Toxicity Study ◽  
Repeated Dose ◽  
Oxide Nanoparticles ◽  
Dermal Toxicity

scholarly journals Ameliorative effect of curcumin and zinc oxide nanoparticles on multiple mechanisms in obese rats with induced type 2 diabetes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shaymaa Abdulmalek ◽  
Asmaa Eldala ◽  
Doaa Awad ◽  
Mahmoud Balbaa
Keyword(s):  
Type 2 Diabetes ◽  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Mapk Pathway ◽  
Akt Pathway ◽  
Oxide Nanoparticles ◽  
Curcumin Nanoparticles ◽  
Ameliorative Effect ◽  
Low Toxicity

AbstractThe present study was carried out to investigate the therapeutic effect of synthesized naturally compounds, curcumin nanoparticles (CurNPs) and metal oxide, zinc oxide nanoparticles (ZnONPs) on a high-fat diet (HFD)/streptozotocin (STZ)-induced hepatic and pancreatic pathophysiology in type 2 diabetes mellitus (T2DM) via measuring AKT pathway and MAPK pathway. T2DM rats were intraperitoneally injected with a low dose of 35 mg/kg STZ after being fed by HFD for 8 weeks. Then the rats have orally received treatments for 6 weeks. HFD/STZ-induced hepatic inflammation, reflected by increased phosphorylation of p38-MAPK pathway’s molecules, was significantly decreased after nanoparticle supplementation. In addition, both nanoparticles significantly alleviated the decreased phosphorylation of AKT pathway. Further, administration of ZnONPs, CurNPs, conventional curcumin, and ZnSO4 (zinc sulfate), as well as metformin, effectively counteracted diabetes-induced oxidative stress and inflammation in the internal hepatic and pancreatic tissues. Based on the results of the current study, ZnONPs and CurNPs could be explored as a therapeutic adjuvant against complications associated with T2DM. Both nanoparticles could effectively delay the progression of several complications by activating AKT pathway and down-regulating MAPK pathway. Our findings may provide an experimental basis for the application of nanoparticles in the treatment of T2DM with low toxicity.

Ameliorative effect of zinc oxide nanoparticles against potassium bromate-mediated toxicity in Swiss albino rats

2019 ◽  
Vol 26 (10) ◽  
pp. 9966-9980 ◽  
Author(s):  
Iftekhar Hassan ◽  
Fohad Mabood Husain ◽  
Rais Ahmad Khan ◽  
Hossam Ebaid ◽  
Jameel Al-Tamimi ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Potassium Bromate ◽  
Albino Rats ◽  
Oxide Nanoparticles ◽  
Ameliorative Effect

Ameliorative effect of zinc oxide nanoparticles on cyclophosphamide induced testicular injury in adult rat

2018 ◽  
Vol 54 ◽  
pp. 80-93 ◽  
Author(s):  
Hoda H. Anan ◽  
Rania A. Zidan ◽  
Samia A. Abd EL-Baset ◽  
Manar M. Ali
Keyword(s):  
Zinc Oxide ◽  
Zinc Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Adult Rat ◽  
Ameliorative Effect ◽  
Testicular Injury

Optical Characteristics of Zinc Oxide Nanoparticles with Surface Modification Using Polyethylene Glycol

2014 ◽  
Vol 29 (10) ◽  
pp. 1039
Author(s):  
TAN Man-Lin ◽  
WANG Yan-Tao ◽  
ZHANG Wei-Li ◽  
FU Dong-Ju ◽  
LI Dong-Shuang ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
Surface Modification ◽  
Polyethylene Glycol ◽  
Zinc Oxide Nanoparticles ◽  
Optical Characteristics ◽  
Oxide Nanoparticles

A comparative study of the antibacterial activity of Quercus robur (Ethanolic extract) and Zinc oxide nanoparticles on Salmonella (In vitro)

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Hams H. H. Alfattli ◽  
Ghufran Zuhair Jiber ◽  
Ghaidaa Gatea Abbass
Keyword(s):  
Zinc Oxide ◽  
Antibacterial Activity ◽  
Zinc Oxide Nanoparticles ◽  
Quercus Robur ◽  
Ethanolic Extract ◽  
Inhibitory Effect ◽  
Significant Inhibition ◽  
Oxide Nanoparticles ◽  
Inhibition Zones

This study which designed to evaluate the inhibitory effect of Ethanolic extract of (Quercusrobur) and Zinc oxide nanoparticles on the growth of one genus of enterobacteriacae (Salmonella). In vitro. For this purpose graduate concentrates for plant extract (50, 100, 200, 400 )mg/ml which prepared and compared with Zinc oxide nanoparticles of different concentration (2, 1, 0.5, 0.25) μg/ml,and examined. The result showed that the studied medicinal plant has antibacterial activity against this bacteria which used. The result showed that the plant has good activity in decrease the growth of this bacteria. The results of the study also showed that the nano-ZnO has very effective antibacterial action against the studied bacteria which was Salmonella,nanoparticles concentrations lead to increasing in the inhibition zones of tested bacterial growth. We also study the effect of three antibiotics Lomefloxacin (LOM), Ciprofloxacin (SIP) and Rifampin (RA) and the result showed,in a comparison within the tested bacteria,Salmonella had a significant inhibition increase in Lomefloxacin ; the ciprofloxacin showed effect on tested bacteria. However,Rifampin does not show any effect on tested bacteria.

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