scholarly journals Co-Delivery of Prednisolone and Curcumin in Human Serum Albumin Nanoparticles for Effective Treatment of Rheumatoid Arthritis

2019 ◽  
Vol Volume 14 ◽  
pp. 9113-9125 ◽  
Author(s):  
Feili Yan ◽  
Hui Li ◽  
Zhirong Zhong ◽  
Meiling Zhou ◽  
Yan Lin ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Effective Treatment ◽  
Albumin Nanoparticles

α-Galactosidase delivery using 30Kc19-human serum albumin nanoparticles for effective treatment of Fabry disease

2016 ◽  
Vol 100 (24) ◽  
pp. 10395-10402 ◽  
Author(s):  
Hong Jai Lee ◽  
Hee Ho Park ◽  
Youngsoo Sohn ◽  
Jina Ryu ◽  
Ju Hyun Park ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Fabry Disease ◽  
Human Serum ◽  
Effective Treatment ◽  
Albumin Nanoparticles

Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain

2010 ◽  
Vol 18 (10) ◽  
pp. 842-848 ◽  
Author(s):  
Anja Zensi ◽  
David Begley ◽  
Charles Pontikis ◽  
Celine Legros ◽  
Larisa Mihoreanu ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Blood Brain Barrier ◽  
Brain Barrier ◽  
Albumin Nanoparticles ◽  
Apolipoprotein A ◽  
Rodent Brain ◽  
Blood Brain

Long-term release of chlorhexidine from dental adhesive resin system using human serum albumin nanoparticles

2014 ◽  
Vol 71 (4) ◽  
pp. 875-886 ◽  
Author(s):  
Hyun-Jin Kim ◽  
Tae-Yub Kwon ◽  
Kyo-Han Kim ◽  
Soon-Taek Kwon ◽  
Dae-Hyun Cho ◽  
...  
Keyword(s):  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Resin System ◽  
Adhesive Resin ◽  
Dental Adhesive ◽  
Albumin Nanoparticles

Regulation of BAX/BCL2 gene expression in breast cancer cells by docetaxel-loaded human serum albumin nanoparticles

2015 ◽  
Vol 32 (7) ◽  
Author(s):  
Marzieh Kordezangeneh ◽  
Shiva Irani ◽  
Reza Mirfakhraie ◽  
Mehdi Esfandyari-Manesh ◽  
Fatemeh Atyabi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Albumin Nanoparticles ◽  
Bcl2 Gene

An effective and safe treatment strategy for rheumatoid arthritis based on human serum albumin and Kolliphor® HS 15

Nanomedicine ◽  
2019 ◽  
Vol 14 (16) ◽  
pp. 2169-2187 ◽  
Author(s):  
Ting Gong ◽  
Pei Zhang ◽  
Caifeng Deng ◽  
Yu Xiao ◽  
Tao Gong ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Therapeutic Strategy ◽  
Inflammatory Cell ◽  
In Vivo Studies ◽  
Targeting Ability

Aim: We aimed to construct human serum albumin-Kolliphor® HS 15 nanoparticles (HSA-HS15 NPs) to overcome the limitations in targeted therapy for rheumatoid arthritis (RA) and enhance the safety of drug-loaded HSA NPs. Methodology: Celastrol (CLT)-loaded HSA-HS15 NPs were prepared and the properties were adequately investigated; the treatment effect were evaluated in RA rats; in vitro and in vivo studies were performed to explain the mechanism. Results: CLT-HSA-HS15 NPs had remarkable treatment ability and enhanced safety in the treatment of RA compared with free CLT and CLT-HSA NPs. Conclusion: HSA-HS15 NPs could be a safe and efficient therapeutic strategy for the treatment of RA, because of the inflammatory targeting ability of albumin, the added HS15 and ELVIS effect (extravasation through leaky vasculature followed by inflammatory cell-mediated sequestration) of nanoparticles.

Human Serum Albumin-TRAIL Conjugate for the Treatment of Rheumatoid Arthritis

2014 ◽  
Vol 25 (12) ◽  
pp. 2212-2221 ◽  
Author(s):  
Hyeong Jun Byeon ◽  
Sun Young Min ◽  
Insoo Kim ◽  
Eun Seong Lee ◽  
Kyung Taek Oh ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum
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