scholarly journals A new strategy for accurate targeted diagnosis and treatment of cutaneous malignant melanoma: dual-mode phase-change lipid nanodroplets as ultrasound contrast agents

2019 ◽  
Vol Volume 14 ◽  
pp. 7079-7093 ◽  
Author(s):  
Hengli Yang ◽  
Wenbin Cai ◽  
Wei Lv ◽  
Ping Zhao ◽  
Yamei Shen ◽  
...  
Keyword(s):  
Malignant Melanoma ◽  
Phase Change ◽  
Contrast Agents ◽  
Cutaneous Malignant Melanoma ◽  
Ultrasound Contrast Agents ◽  
Diagnosis And Treatment ◽  
Dual Mode ◽  
Ultrasound Contrast ◽  
New Strategy

scholarly journals From Micro- to Nano-Multifunctional Theranostic Platform: Effective Ultrasound Imaging Is Not Just a Matter of Scale

2018 ◽  
Vol 17 ◽  
pp. 153601211877821 ◽  
Author(s):  
Sara Zullino ◽  
Monica Argenziano ◽  
Ilaria Stura ◽  
Caterina Guiot ◽  
Roberta Cavalli
Keyword(s):  
Diagnostic Imaging ◽  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Imaging ◽  
Tumor Tissue ◽  
Ultrasound Contrast Agents ◽  
Acoustic Droplet Vaporization ◽  
Droplet Vaporization ◽  
Enhanced Permeability And Retention ◽  
Ultrasound Contrast

Ultrasound Contrast Agents (UCAs) consisting of gas-filled-coated Microbubbles (MBs) with diameters between 1 and 10 µm have been used for a number of decades in diagnostic imaging. In recent years, submicron contrast agents have proven to be a viable alternative to MBs for ultrasound (US)-based applications for their capability to extravasate and accumulate in the tumor tissue via the enhanced permeability and retention effect. After a short overview of the more recent approaches to ultrasound-mediated imaging and therapeutics at the nanoscale, phase-change contrast agents (PCCAs), which can be phase-transitioned into highly echogenic MBs by means of US, are here presented. The phenomenon of acoustic droplet vaporization (ADV) to produce bubbles is widely investigated for both imaging and therapeutic applications to develop promising theranostic platforms.

scholarly journals Phase Change Ultrasound Contrast Agents with a Photopolymerized Diacetylene Shell

Langmuir ◽  
2019 ◽  
Vol 35 (31) ◽  
pp. 10116-10127 ◽  
Author(s):  
Yosra Toumia ◽  
Barbara Cerroni ◽  
Fabio Domenici ◽  
Heiko Lange ◽  
Livia Bianchi ◽  
...  
Keyword(s):  
Phase Change ◽  
Contrast Agents ◽  
Ultrasound Contrast Agents ◽  
Ultrasound Contrast

Development and application of ultrasound contrast agents in biomedicine

2021 ◽  
Author(s):  
Yu Wang ◽  
Hailin Cong ◽  
Song Wang ◽  
Bing Yu ◽  
Youqing Shen
Keyword(s):  
Molecular Imaging ◽  
Contrast Agents ◽  
Molecular Level ◽  
Rapid Development ◽  
Ultrasound Contrast Agents ◽  
Diagnosis And Treatment ◽  
Imaging Diagnosis ◽  
Integrated Diagnosis ◽  
Ultrasound Contrast

With the rapid development of molecular imaging, ultrasound (US) medicine has changed from traditional imaging diagnosis to integrated diagnosis and treatment at the molecular level. Ultrasound contrast agents (UCAs) play...

scholarly journals An evaluation of the sonoporation potential of low-boiling point phase-change ultrasound contrast agents in vitro

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Samantha M. Fix ◽  
Anthony Novell ◽  
Yeoheung Yun ◽  
Paul A. Dayton ◽  
Christopher B. Arena
Keyword(s):  
Phase Change ◽  
Contrast Agents ◽  
Boiling Point ◽  
Ultrasound Contrast Agents ◽  
Ultrasound Contrast
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