scholarly journals Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies

2011 ◽  
pp. 611 ◽  
Author(s):  
Farboud ◽  
Farboud ◽  
Tabakhi
Keyword(s):  
In Vivo Studies ◽  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle

scholarly journals Solid lipid nanoparticle induced apoptosis of macrophages via a mitochondrial-dependent pathway in vitro and in vivo

2019 ◽  
Vol Volume 14 ◽  
pp. 3283-3295 ◽  
Author(s):  
Wan-Li Liang ◽  
Lan Xiao ◽  
Hong-Wei Gu ◽  
Xiao-Jun Li ◽  
Yu-Sang Li ◽  
...  
Keyword(s):  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle ◽  
Induced Apoptosis ◽  
Dependent Pathway

Application of Novel Solid Lipid Nanoparticle (SLN)-Gene Vector Formulations Based on a Dimeric HIV-1 TAT-Peptide in Vitro and in Vivo

2004 ◽  
Vol 21 (9) ◽  
pp. 1662-1669 ◽  
Author(s):  
Carsten Rudolph ◽  
Ulrike Schillinger ◽  
Aurora Ortiz ◽  
Kerstin Tabatt ◽  
Christian Plank ◽  
...  
Keyword(s):  
Gene Vector ◽  
Tat Peptide ◽  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle ◽  
Hiv 1

scholarly journals Solid Lipid Nanoparticle Formulations of Docetaxel Prepared with High Melting Point Triglycerides: In Vitro and in Vivo Evaluation

2014 ◽  
Vol 11 (4) ◽  
pp. 1239-1249 ◽  
Author(s):  
Youssef Wahib Naguib ◽  
B. Leticia Rodriguez ◽  
Xinran Li ◽  
Stephen D. Hursting ◽  
Robert O. Williams ◽  
...  
Keyword(s):  
Melting Point ◽  
High Melting ◽  
Solid Lipid Nanoparticle ◽  
High Melting Point ◽  
In Vivo Evaluation ◽  
Solid Lipid ◽  
Lipid Nanoparticle

scholarly journals Preparation and Evaluation of Carbamazepine Solid Lipid Nanoparticle for Alleviating Seizure Activity in Pentylenetetrazole-Kindled Mice

Molecules ◽  
2019 ◽  
Vol 24 (21) ◽  
pp. 3971 ◽  
Author(s):  
Mona Qushawy ◽  
Kousalya Prabahar ◽  
Mohammed Abd-Alhaseeb ◽  
Shady Swidan ◽  
Ali Nasr
Keyword(s):  
Histopathological Examination ◽  
In Vitro Release ◽  
Aqueous Dispersion ◽  
Entrapment Efficiency ◽  
Anticonvulsant Effect ◽  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle

Objectives: The study aimed to prepare carbamazepine in solid lipid nanoparticle form (CBZ-SLN) in order to enhance its anticonvulsant effect. Method: Eight formulations of CBZ-SLNs were prepared by homogenization and ultra-sonication techniques. Results: The prepared CBZ-SLN showed a high entrapment efficiency% (39.66 ± 2.42%–71.91 ± 1.21%), a small particle size (45.11 ± 6.72–760.7 ± 5.25 nm), and a negative zeta potential (from −21.5 ± 1.02 to −38.4 ± 1.32 mv). The in vitro release study showed the slow release of CBZ from SLNs compared to CBZ aqueous dispersion (p < 0.05). The infrared spectroscopy and the thermal analysis revealed the compatibility of the drug with other ingredients and the presence of drug in the more soluble amorphous estate, respectively. The in vivo study on mice revealed that the CBZ-SLN had a higher anticonvulsant efficacy than CBZ aqueous dispersion after a lethal and chronic dose of pentylenetetrazole (PTZ) (p < 0.05). The histopathological examination of the hippocampus revealed a decrease in the percentage of degeneration in mice treated with the CBZ-SLN compared to the PTZ and CBZ groups. Conclusion: CBZ can be formulated as SLN with higher anticonvulsant activity than free CBZ aqueous dispersion.

Solid lipid nanoparticle loaded with paromomycin: in vivo efficacy against Leishmania tropica infection in BALB/c mice model

2016 ◽  
Vol 100 (16) ◽  
pp. 7051-7060 ◽  
Author(s):  
Maryam Heidari-Kharaji ◽  
Tahereh Taheri ◽  
Delaram Doroud ◽  
Sima Habibzadeh ◽  
Sima Rafati
Keyword(s):  
Leishmania Tropica ◽  
Solid Lipid Nanoparticle ◽  
Mice Model ◽  
In Vivo Efficacy ◽  
Solid Lipid ◽  
Lipid Nanoparticle

Design and In Vitro Evaluation of Solid-Lipid Nanoparticle Drug Delivery for Aceclofenac

2012 ◽  
Vol 33 (1) ◽  
pp. 96-102 ◽  
Author(s):  
Narra Kishore ◽  
U. M. Dhanalekshmi ◽  
M. D. Raja ◽  
Saranya Bhavani ◽  
P. Neelakanta Reddy
Keyword(s):  
Drug Delivery ◽  
Solid Lipid Nanoparticle ◽  
In Vitro Evaluation ◽  
Solid Lipid ◽  
Lipid Nanoparticle ◽  
Nanoparticle Drug Delivery
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