scholarly journals Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of paclitaxel

2017 ◽  
Vol Volume 12 ◽  
pp. 8779-8799 ◽  
Author(s):  
Xiaomin Zhang ◽  
Yibo Wu ◽  
Min Zhang ◽  
Jing Mao ◽  
Yun Wu ◽  
...  
Keyword(s):  
Tumor Targeting ◽  
Polymeric Micelle ◽  
Sodium Cholate ◽  
Targeting Delivery ◽  
Micelle System

Development of cholate conjugated hybrid polymeric micelles for FXR receptor mediated effective site-specific delivery of paclitaxel

2018 ◽  
Vol 42 (20) ◽  
pp. 17021-17032 ◽  
Author(s):  
Sivaraj Mehnath ◽  
Mukherjee Arjama ◽  
Mariappan Rajan ◽  
Murugaraj Jeyaraj
Keyword(s):  
Cholic Acid ◽  
Tumor Targeting ◽  
Polymeric Micelles ◽  
Polymeric Micelle ◽  
Site Specific ◽  
Effective Delivery ◽  
Effective Site ◽  
Micelle System

The aim of the present study was to explore the tumor targeting potential of a cholic acid (CA) conjugated polymeric micelle system for the effective delivery of paclitaxel (PTX).

Adoptive CD8+T-cell grafted with liposomal immunotherapy drugs to counteract the immune suppressive tumor microenvironment and enhance therapy for melanoma

Nanoscale ◽  
2021 ◽  
Author(s):  
Simeng Liu ◽  
Huimin Liu ◽  
Xiaoshuang Song ◽  
Ailing Jiang ◽  
Yuchuan Deng ◽  
...  
Keyword(s):  
T Cells ◽  
T Cell ◽  
Tumor Microenvironment ◽  
Cell Viability ◽  
Tumor Targeting ◽  
Cd8 T Cell ◽  
Targeting Delivery ◽  
Immunosuppressive Tumor Microenvironment

Efficient tumor-targeting delivery of CpG or BMS-202 by adoptive T-cells coupled with drug loaded liposomes reversed the immunosuppressive tumor microenvironment, restoring T cell viability and effectively inhibiting the growth of melanoma.

scholarly journals In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection

2019 ◽  
Vol 109 ◽  
pp. 779-787 ◽  
Author(s):  
Débora V.C. Mendonça ◽  
Grasiele S.V. Tavares ◽  
Daniela P. Lage ◽  
Tauane G. Soyer ◽  
Lívia M. Carvalho ◽  
...  
Keyword(s):  
Polymeric Micelle ◽  
Leishmania Amazonensis ◽  
Micelle System

Materializing sequential killing of tumor vasculature and tumor cells via targeted polymeric micelle system

2011 ◽  
Vol 149 (3) ◽  
pp. 299-306 ◽  
Author(s):  
Yiguang Wang ◽  
Tingyuan Yang ◽  
Xun Wang ◽  
Wenbing Dai ◽  
Jiancheng Wang ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Tumor Vasculature ◽  
Polymeric Micelle ◽  
Micelle System

scholarly journals Dual disassembly and biological evaluation of enzyme/oxidation-responsive polyester-based nanoparticulates for tumor-targeting delivery

2018 ◽  
Vol 172 ◽  
pp. 608-617 ◽  
Author(s):  
Sung Hwa Hong ◽  
Kevin Larocque ◽  
Dilan B. Jaunky ◽  
Alisa Piekny ◽  
Jung Kwon Oh
Keyword(s):  
Tumor Targeting ◽  
Biological Evaluation ◽  
Targeting Delivery

Biomimetic Drug Delivery Systems Oriented by Biological Function in Tumor Targeting

2021 ◽  
Vol 22 ◽  
Author(s):  
Rui Wang ◽  
Xianyi Sha
Keyword(s):  
Drug Delivery ◽  
Tumor Targeting ◽  
Drug Delivery Systems ◽  
Biological Function ◽  
Delivery Systems ◽  
Biological Functions ◽  
Simple Preparation ◽  
Targeting Delivery ◽  
Clinical Transformation ◽  
Endogenous Substances

: The emergence of nanoscale drug delivery systems provides new opportunities for targeting delivery of chemotherapeutic drugs and has achieved excellent results. In recent years, with the arising of the concept of intelligent drug delivery systems, the design and preparation of carriers have become more and more complicated, which is not conducive to clinical transformation. Researchers are gradually focusing on biomimetic nanoscale drug delivery systems, trying to combine the physicochemical properties of nanoscale carriers with the natural biological functions of endogenous substances, so as to boost tumor targeting delivery. In this article, we first classify and introduce biomimetic nanoscale drug delivery systems, and then emphasize their unique biological functions. The biomimetic nanoscale drug delivery systems have the advantages of simple preparation, powerful functions, and low immunogenicity, having a good application prospect.

scholarly journals Treatment of murine visceral leishmaniasis using an 8-hydroxyquinoline-containing polymeric micelle system

2016 ◽  
Vol 65 (6) ◽  
pp. 728-736 ◽  
Author(s):  
Mariana Costa Duarte ◽  
Letícia Martins dos Reis Lage ◽  
Daniela Pagliara Lage ◽  
Vívian Tamietti Martins ◽  
Ana Maria Ravena Severino Carvalho ◽  
...  
Keyword(s):  
Visceral Leishmaniasis ◽  
Polymeric Micelle ◽  
Micelle System

Redox stimuli-responsive hollow mesoporous silica nanocarriers for targeted drug delivery in cancer therapy

2016 ◽  
Vol 1 (6) ◽  
pp. 480-487 ◽  
Author(s):  
Ye Tian ◽  
Ranran Guo ◽  
Yunfeng Jiao ◽  
Yangfei Sun ◽  
Shun Shen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Targeted Drug Delivery ◽  
Tumor Targeting ◽  
Mesoporous Silica Nanoparticles ◽  
Stimuli Responsive ◽  
Disulfide Linkages ◽  
Targeting Delivery ◽  
Targeted Drug ◽  
Hollow Mesoporous Silica

Transferrin-capped hollow mesoporous silica nanoparticles through disulfide linkages realize tumor-targeting delivery and glutathione-induced drug release.

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