scholarly journals High-intensity focused ultrasound-triggered nanoscale bubble-generating liposomes for efficient and safe tumor ablation under photoacoustic imaging monitoring

2017 ◽  
Vol Volume 12 ◽  
pp. 4647-4659 ◽  
Author(s):  
Gang Feng ◽  
Lan Hao ◽  
Chunyan Xu ◽  
Haitao Ran ◽  
Yuanyi Zheng ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Photoacoustic Imaging ◽  
Tumor Ablation ◽  
High Intensity Focused Ultrasound

scholarly journals Small PLGA nanocapsules Co-encapsulating copper sulfide nanodots and fluorocarbon compound for photoacoustic imaging-guided HIFU synergistic therapy

RSC Advances ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 4514-4524 ◽  
Author(s):  
Minghua Yao ◽  
Ming Ma ◽  
Huixiong Xu ◽  
Xiaoxia Pan ◽  
Guang Xu ◽  
...  
Keyword(s):  
High Intensity ◽  
Copper Sulfide ◽  
Focused Ultrasound ◽  
Photoacoustic Imaging ◽  
High Intensity Focused Ultrasound ◽  
Ultrasound Therapy ◽  
Organic Hybrid

A nanometer-sized inor-ganic/organic hybrid enhancement agent is constructed for photoacoustic imaging-guided high intensity focused ultrasound therapy.

scholarly journals Novel Therapeutic Method for Unresectable Pancreatic Cancer-The Impact of the Long-Term Research in Therapeutic Effect of High-Intensity Focused Ultrasound (HIFU) Therapy

2021 ◽  
Vol 28 (6) ◽  
pp. 4845-4861
Author(s):  
Atsushi Sofuni ◽  
Yasutsugu Asai ◽  
Takayoshi Tsuchiya ◽  
Kentaro Ishii ◽  
Reina Tanaka ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Symptom Relief ◽  
Tumor Ablation ◽  
High Intensity Focused Ultrasound ◽  
Therapeutic Effects ◽  
Unresectable Pancreatic Cancer ◽  
Advanced Therapy ◽  
The Impact

High-intensity focused ultrasound (HIFU) is a novel advanced therapy for unresectable pancreatic cancer (PC). HIFU therapy with chemotherapy is being promoted as a novel method to control local advancement by tumor ablation. We evaluated the therapeutic effects of HIFU therapy in locally advanced and metastatic PC. PC patients were treated with HIFU as an optional local therapy and systemic chemotherapy. The FEP-BY02 (Yuande Bio-Medical Engineering) HIFU device was used under ultrasound guidance. Of 176 PC patients, 89 cases were Stage III and 87 were Stage IV. The rate of complete tumor ablation was 90.3%, while that of symptom relief was 63.8%. The effectiveness on the primary lesions were as follows: complete response (CR): n = 0, partial response (PR): n = 21, stable disease (SD): n = 105, and progressive disease (PD): n = 47; the primary disease control rate was 71.0%. Eight patients underwent surgery. The median survival time (MST) after diagnosis for HIFU with chemotherapy compared to chemotherapy alone (100 patients in our hospital) was 772.3 vs. 346.6 days (p < 0.001). Compared with chemotherapy alone, the combination of HIFU therapy and chemotherapy demonstrated significant prolongation of prognosis. This study suggests that HIFU therapy has the potential to be a novel combination therapy for unresectable PC.

Liver Tumor Ablation with High-Intensity Focused Ultrasound

1993 ◽  
Vol 10 (02) ◽  
pp. 125-131 ◽  
Author(s):  
Kenyon Kopecky ◽  
Rong Yang ◽  
Narendra Sanghvi ◽  
Frederick Rescorla
Keyword(s):  
Liver Tumor ◽  
High Intensity ◽  
Focused Ultrasound ◽  
Tumor Ablation ◽  
High Intensity Focused Ultrasound
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