scholarly journals Preparation and characterization of superparamagnetic iron oxide nanoparticles for magnetically guided drug delivery

2018 ◽  
Vol Volume 13 ◽  
pp. 43-46 ◽  
Author(s):  
Pramod Kumar ◽  
Shrish Agnihotri ◽  
Indrajit Roy
Keyword(s):  
Drug Delivery ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles

ß-Amido Acid Functionalised Superparamagnetic Iron Oxide Nanoparticles as a Novel Carrier for Efficient Delivery of Doxorubicine

2017 ◽  
Vol 41 (3) ◽  
pp. 129-135
Author(s):  
Fatemeh Ebrahimi ◽  
Maryam Karimi ◽  
Hasan Sereshti ◽  
Mohsen Yousefifar
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Precipitation Method ◽  
Hydrodynamic Diameter ◽  
Oxide Nanoparticles ◽  
Amido Acid

Superparamagnetic iron oxide nanoparticles are increasingly used in medical applications due to their unique physical properties. They are useful carriers for delivering antitumour drugs in targeted cancer treatment. In this study, amido acid-functionalised magnetic nanoparticles (AAFMNs) are used as drug-delivery vehicles for doxorubicine as an efficient tool for the treatment of cancer. Magnetic iron oxide nanoparticles were synthesised using a co-precipitation method. The prepared iron oxide nanoparticles were then functionalised with amido acid functional groups. Finally, the synthesised AAFMNs were used for the delivery of doxorubicine. AAFMNs were characterised by Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, thermogravimetric analysis and zeta potential. An in vitro-determined hydrodynamic diameter of ∼80 nm suggested their applicability for this purpose. The findings show that AAFMNs are a promising tool for potential magnetic drug delivery.

Synthesis and characterization of multifunctional superparamagnetic iron oxide nanoparticles (SPION)/C60 nanocomposites assembled by fullerene–amine click chemistry

RSC Advances ◽  
2016 ◽  
Vol 6 (74) ◽  
pp. 70374-70382 ◽  
Author(s):  
Manuel Cano ◽  
Rebeca Núñez-Lozano ◽  
Yves Dumont ◽  
Chantal Larpent ◽  
Guillermo de la Cueva-Méndez
Keyword(s):  
Iron Oxide ◽  
Click Chemistry ◽  
Iron Oxide Nanoparticles ◽  
Antioxidant Activities ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Synthesis And Characterization ◽  
Oxide Nanoparticles

We used fullerene–amine click chemistry for the fabrication of SPION/C60 nanocomposites that bring together the superparamagnetic character conferred by the SPION-core and the photochemical and antioxidant activities provided by the C60.

Sign in / Sign up

Export Citation Format

Share Document