scholarly journals Risk Factors of Drug Resistance and the Potential Risk of HIV-1 Transmission of Patients with ART Virological Failure: A Population-Based Study in Sichuan, China

2021 ◽  
Vol Volume 14 ◽  
pp. 5219-5233
Author(s):  
Chang Zhou ◽  
Rui Kang ◽  
Shu Liang ◽  
Teng Fei ◽  
Yiping Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drug Resistance ◽  
Virological Failure ◽  
Potential Risk ◽  
Population Based ◽  
Population Based Study ◽  
Hiv 1

scholarly journals Prevalence of Intracranial Aneurysm in Patients With Aortic Disease in Korea: A Nationwide Population‐Based Study

2021 ◽  
Vol 10 (6) ◽  
Author(s):  
Jihye Song ◽  
Yong Cheol Lim ◽  
Inseok Ko ◽  
Jong‐Yeup Kim ◽  
Dong‐Kyu Kim
Keyword(s):  
Risk Factors ◽  
Intracranial Aneurysm ◽  
Potential Risk ◽  
National Sample ◽  
Aortic Disease ◽  
Population Based ◽  
Aortic Aneurysms ◽  
Population Based Study ◽  
Potential Risk Factors ◽  
Representative Cohort

Background Patients with aortic disease (AD) might have a higher prevalence of intracranial aneurysm (IA). The present study evaluated the prevalence of IA in patients with AD and identified potential risk factors of IA using nationwide representative cohort sample data. Methods and Results We defined AD as both aortic dissections and aortic aneurysms. This study used a nationwide representative cohort sample from the Korea National Health Insurance Service–National Sample Cohort database from 1.1million patients. Using χ 2 or Fisher’s exact tests, the prevalence of the IA in patients with AD and potential risk factors for their concurrence were analyzed. The prevalence of IA in patients with AD was 6.8% (155/2285). The adjusted odds ratios (OR) for having concurrent IA in patients with AD was 3.809 (95% CI, 3.191–4.546; P <0.01). Patients with AD and hypertension were >19 times more likely to be affected by IA (adjusted OR, 18.679; 95% CI, 16.555–21.076; P <0.01). Patients with AD and diabetes mellitus, old age (>60 years), and male sex were >4, 3, and 2 times more likely to be affected by IA, respectively (adjusted OR, 4.291, 3.469, and 1.983, respectively; 95% CI, 3.914–4.704, 3.152–3.878, and 1.779–2.112, respectively). Subgroup analysis with socioeconomic status or disability revealed that the prevalence of IA was significantly higher in all groups. Conclusions In the current population‐based study, the prevalence of IA in patients with AD was quadrupled compared with that in the general population. Early IA screening might be considered among patients with AD for appropriate management.

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