scholarly journals Methicillin and Vancomycin Resistant Staphylococcus aureus and Associated Factors from Surgical Ward Inpatients at Debre Markos Referral Hospital, Northwest Ethiopia

2021 ◽  
Vol Volume 14 ◽  
pp. 3053-3062
Author(s):  
Samrawit Tefera ◽  
Tewachew Awoke ◽  
Daniel Mekonnen
Keyword(s):  
Staphylococcus Aureus ◽  
Associated Factors ◽  
Northwest Ethiopia ◽  
Referral Hospital ◽  
Surgical Ward ◽  
Vancomycin Resistant ◽  
Debre Markos

scholarly journals Methicillin and Vancomycin Resistant Staphylococcus aureus and Associated Factors from Surgical Ward Inpatients at Debre Markos Referral Hospital, Northwest Ethiopia

2020 ◽  
Author(s):  
Samrawit Tefera Demsie ◽  
Tewachew Awoke ◽  
Daniel Mekonnen
Keyword(s):  
Staphylococcus Aureus ◽  
Associated Factors ◽  
Northwest Ethiopia ◽  
Referral Hospital ◽  
Mannitol Salt Agar ◽  
Surgical Ward ◽  
Hospital Infection Control ◽  
Multiple Variables ◽  
Vancomycin Resistant ◽  
Debre Markos

Abstract Background: Staphylococcus aureus is one of the leading wound infections. It is considered as a super bug. The epidemiology of Methicillin Resistant S. aureus (MRSA) and Vancomycin Resistant S. aureus (VRSA) is not well studied in Ethiopia particularly in Debre Markos Referral Hospital (DMRH). The objective of the study was to determine the prevalence of MRSA and VRSA and associated factors from wound cases admitted to surgical ward in DMRH, Northwest Ethiopia.Methods: A cross-sectional study was conducted from February-April 2020 at DMRH. A structured questionnaire was used to collect demographic and clinical characteristics. Wound swabs were collected using sterile cotton swab followed by culturing on Blood agar and Mannitol Salt agar. Then isolates were characterized by gram stain and biochemical tests. The presence of MRSA and VRSA was determined using the cefoxitin (30μg) antibiotic disc diffusion and vancomycin E-test, respectively. The data was analyzed using Statistical Package for Social Sciences, version 20 software. P-value <0.05 was considered statistically significant.Results: A total of 242 wound cases were enrolled and a majority of them were males (172, 71.1%). Among the total wound cases, the isolation rate of S. aureus was 29.3%. The proportion of MRSA was 13.22% and that of VRSA was 4.1%. The proportion of vancomycin intermediate S. aureus (VISA) was gauged at 4.5%. Hospital stay >72h (p=0.014), wound depth (p=0.043), antibiotic use (p=0.017) and previous history of wound infection (p=0.001) showed statistical significant association with MRSA. No variables showed significant association with VRSA.Conclusion: High proportions of S. aureus isolates are resistant to methicillin and vancomycin. Moreover, multiple variables demonstrated associations with drug resistance. Hence, hospital infection control and antibiotic stewardship program shall be strengthened.

Prevalence of Intestinal Parasites and Associated Factors among HIV Patients who had Follow up at Debre Markos Referral Hospital,Northwest Ethiopia,from 2015-2019.

2019 ◽  
Author(s):  
Wodaje Gietaneh ◽  
Ayalnesh Agegne ◽  
Getnet Gedif
Keyword(s):  
Immune Deficiency ◽  
Associated Factors ◽  
Intestinal Parasites ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Northwest Ethiopia ◽  
Referral Hospital ◽  
Human Immune Deficiency Virus ◽  
Debre Markos

Abstract Objective To assess prevalence of intestinal parasite and associated factors among patients with human immune deficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) in Debre markos referral hospital, Amhara region, Ethiopia from 2015-2019RESULTS This study revealed that, out of 380 patients, the prevalence of intestinal parasites was found to be 24.2% with95%CI (18.9, 28.4). The most predominant parasite was both forms of Entamoeba histolytica 11.3% followed by G.lambilia 8.9%, Strongyloides sterocoralis 2.4%, but A.lumbricoid 0.8% and H.worm 0.8% were the least detected. ART status had significant association with prevalence of intestinal parasites (AOR =3.566, CI: 1.882, 6.758).

scholarly journals Magnitude of anemia and associated factors among children aged 6–59 months at Debre Markos referral hospital, Northwest Ethiopia: a hospital-based cross-sectional study

2021 ◽  
Vol 47 (1) ◽  
Author(s):  
Yoseph Merkeb Alamneh ◽  
Tadesse Yirga Akalu ◽  
Abtie Abebaw Shiferaw ◽  
Aytenew Atnaf
Keyword(s):  
Public Health ◽  
Associated Factors ◽  
Family Income ◽  
Dietary Diversity ◽  
Intestinal Parasites ◽  
Public Health Problem ◽  
Northwest Ethiopia ◽  
Referral Hospital ◽  
Cross Sectional ◽  
Debre Markos

Abstract Background Anemia, the most common micro-nutrient deficiency disorder, is the world’s second leading cause of morbidity and morbidity, affecting 24.8% of the population, of which 47.4% are under-five children. The prevalence of anemia ranges from 44 to 56% in Ethiopia. Although its magnitude has shown decreases across regions; it continues to be a significant public health problem, particularly in developing countries including Ethiopia. Despite this evidence, the magnitude and associated factors of anemia was not systematically explored and there is a limited information or limited evidences in the study area. Hence, the aim of this study was to assess the magnitude and associated factors of anemia among children aged 6–59 months attending at Debre Markos Referral Hospital, Northwest Ethiopia. Methods A hospital-based cross-sectional study was conducted at Debre Markos referral hospital Northwest Ethiopia from September 30 to December 30, 2019. Data on socio-demographic and socio-economic factors, health and nutritional features of children and their mothers were obtained using pre-tested structured questionnaires in a face-to-face interview with child care providers. Blood samples and stool examination for intestinal parasites were performed. Hemoglobin level was analyzed using the HemoCue device (HemoCueHb 301). The collected data were coded, cleared and entered into Epi-Data version 3.1, and analyzed using Stata version 14 software. To identify candidates and predictor variables, bivariate and multivariate logistic regressions were applied respectively. The significance level was determined at a confidence interval of 95% at p-value < 0.05. Results Of the total of 341 participants planned to be participated, about 310 mother-child pairs participated in the study, giving a response rate of 91%; and data were collected from children as well as their parents or guardians. In this study, the magnitude of anemia was 11.9% (95% CI, 8.5, 16.2%). Poor dietary diversity (AOR = 2.3; 95% CI: 1.12, 5.14), food-insecure households (AOR = 3.24; 95% CI: 1.85, 4.52), complementary feeding initiation time (AOR = 3.20; 95% CI:1.23, 6.61), intestinal parasites infection (AOR = 3.20; 95% CI:1.23, 6.61) and family income (AOR = 2.87; 95% CI:1.57, 5.0) were found to be factors significantly associated with anemia. Conclusion Overall, anemia is considered a public health problem among children aged 6–59 months attending at Debre Markos referral hospital, based on the cut-off point of the World Health Organization. Poor dietary diversity, complementary feeding initiation time, household food insecurity, intestinal parasite infection and family income were significantly associated with childhood anemia. Thus, it needs for proven interventions in public health such as food diversification, anti-helmintic drug provision and household food security. In addition, educating women about nutrition and diet diversification, as well as involving them in alternative sources of income-generating activity, can be vital in the study area.

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