scholarly journals Microbial Spectrum and Resistance Patterns in Ocular Infections: A 15-Year Review in East China

2021 ◽  
Vol Volume 14 ◽  
pp. 2165-2171
Author(s):  
Chunhong Liu ◽  
Baixing Ding ◽  
Jian Ji ◽  
Zhujian Wang ◽  
Huiwen Chen ◽  
...  
Keyword(s):  
East China ◽  
Ocular Infections ◽  
Resistance Patterns ◽  
Microbial Spectrum

scholarly journals Bacterial Spectrum and Antibiotic Resistance Patterns of Ocular Infection: Differences between External and Intraocular Diseases

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Nan Wang ◽  
Qian Yang ◽  
Yiwei Tan ◽  
Liping Lin ◽  
Qiang Huang ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Retrospective Study ◽  
Ocular Surface ◽  
Bacterial Infections ◽  
Ocular Infection ◽  
Vitreous Fluid ◽  
Ocular Infections ◽  
Resistance Patterns ◽  
Antibiotic Resistance Patterns ◽  
Microbial Spectrum

This study aimed to compare the differences of microbial spectrum and antibiotic resistance patterns between external and intraocular bacterial infections in an eye hospital in South China. A total of 737 bacteria isolates from suspected ocular infections were included in this retrospective study covering the period 2010–2013. The organisms cultured from the ocular surface (cornea, conjunctiva) accounted for the majority of the isolates (82.77%,n= 610), followed by the intraocular (aqueous humor, vitreous fluid), which accounted for 17.23% (n= 127). The top three species accounting for the external ocular infections wereS. epidermidis(35.25%),P. aeruginosa(8.03%), andS. simulans(4.43%). The top three species for the intraocular infections wereS. epidermidis(14.96%),S. hominis(8.66%), andB. subtilis(7.87%). The bacteria from the external ocular surface were more sensitive to neomycin, while those from the intraocular specimens were more sensitive to levofloxacin (P< 0.01). Multidrug resistance was found in 89 bacteria (12.08%), including isolates from both external (13.28%) and intraocular samples (6.30%). The results of this study indicate that the bacteria spectrum of external and intraocular infections is variable in the setting. A high percentage of bacterial organisms were found to be primarily susceptible to neomycin for external infection and levofloxacin for intraocular infection.

scholarly journals Antibiotic Resistance Pattern of Staphylococcus Aureus Isolated From Pediatrics With Ocular Infections: A 6-Year Hospital-Based Study in China

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiao-Yu Zheng ◽  
Bonnie Nga Kwan Choy ◽  
Ming-Ming Zhou ◽  
Zheng-Yan Zhao
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Resistance Rate ◽  
Resistance Pattern ◽  
Ocular Infection ◽  
Ocular Infections ◽  
Resistance Patterns ◽  
Mrsa Infection ◽  
Resistance Rates ◽  
Antibiotic Resistance Patterns

Staphylococcus aureus (S. aureus) is an important pathogen of ocular infections in pediatrics. The study aimed to identify the prevalence and resistance pattern of S. aureus, especially methicillin-resistant S. aureus (MRSA), in Chinese children with ocular infections. All patients with S. aureus infections were reviewed at a tertiary children's hospital during 2015–2020, and those with ocular infections were investigated for susceptibility results. Of 1,668 S. aureus strains, there were 177 unique isolates from ocular infection. Among them, 45 (25.4%) were MRSA and 132 (74.6%) were methicillin-sensitive S. aureus (MSSA). The proportion of MRSA did not change over time. Most of the strains were obtained from the neonate ward and ophthalmology department (n = 88, 49.7%, and n = 85, 48.0%, respectively), while eye secretion and pus were the main specimen types (n = 128, 72.3%, and n = 37, 20.9%, respectively). MRSA was significantly resistant against penicillin class (97.8%), erythromycin (71.1%), clindamycin (71.1%), and tetracycline (32.1%), with a high multidrug resistance (MDR) rate of 71.1%. However, MRSA was highly sensitive to levofloxacin. Resistance rates against erythromycin and ciprofloxacin as well as MDR percentage all increased among MSSA in children above 1 year of age, ophthalmology department, and outpatient population and decreased in eye secretion specimen. The mean resistance percentage remained stable for MRSA and MSSA during the study period. The survey of ocular S. aureus pathogens in pediatrics and their antibiotic resistance patterns helps in clinical treatment. MRSA with many strains demonstrating MDR is highly prevalent in children with ocular infections in Southeast China. Levofloxacin is an effective topical antibiotic for ocular MRSA infection, while erythromycin has a high resistance rate. The antibiotic resistance patterns of MRSA and MSSA differs and varies by different stratifications. A cautious use of antibiotics should be considered.

Changing antimicrobial resistance patterns and trends of Shigella isolates in Ningbo, mid-east China, 2005–2013

2015 ◽  
Vol 45 (5) ◽  
pp. 559-560 ◽  
Author(s):  
Qifa Song ◽  
Wenping Lin ◽  
Hong Gao ◽  
Yuanbin Yang ◽  
Jingye Xu ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
East China ◽  
Resistance Patterns

Dual stain kit for the microscopic gram classification of ocular infection bacteria

1993 ◽  
Vol 51 ◽  
pp. 248-249
Author(s):  
Jacob S. Hanker ◽  
Dale N. Holdren ◽  
Kenneth L. Cohen ◽  
Beverly L. Giammara
Keyword(s):  
Contact Lenses ◽  
Ocular Infection ◽  
Gram Negative Bacteria ◽  
Gram Negative ◽  
Gram Staining ◽  
Ocular Infections ◽  
Different Types ◽  
Culture Positive ◽  
Increased Susceptibility

Keratitis and conjunctivitis (infections of the cornea or conjunctiva) are ocular infections caused by various bacteria, fungi, viruses or parasites; bacteria, however, are usually prominent. Systemic conditions such as alcoholism, diabetes, debilitating disease, AIDS and immunosuppressive therapy can lead to increased susceptibility but trauma and contact lens use are very important factors. Gram-negative bacteria are most frequently cultured in these situations and Pseudomonas aeruginosa is most usually isolated from culture-positive ulcers of patients using contact lenses. Smears for staining can be obtained with a special swab or spatula and Gram staining frequently guides choice of a therapeutic rinse prior to the report of the culture results upon which specific antibiotic therapy is based. In some cases staining of the direct smear may be diagnostic in situations where the culture will not grow. In these cases different types of stains occasionally assist in guiding therapy.

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