scholarly journals Potential role of the antimicrobial peptide Tachyplesin III against multidrug-resistant P. aeruginosa and A. baumannii coinfection in an animal model

2019 ◽  
Vol Volume 12 ◽  
pp. 2865-2874 ◽  
Author(s):  
Jialong Qi ◽  
Ruiyu Gao ◽  
Cunbao Liu ◽  
Bin Shan ◽  
Fulan Gao ◽  
...  
Keyword(s):  
Animal Model ◽  
Antimicrobial Peptide ◽  
Potential Role ◽  
Multidrug Resistant

scholarly journals Potential role of an antimicrobial peptide, KLK in inhibiting lipopolysaccharide-induced macrophage inflammation

PLoS ONE ◽  
2017 ◽  
Vol 12 (8) ◽  
pp. e0183852 ◽  
Author(s):  
Pornpimon Jantaruk ◽  
Sittiruk Roytrakul ◽  
Sutthirat Sitthisak ◽  
Duangkamol Kunthalert
Keyword(s):  
Antimicrobial Peptide ◽  
Potential Role

scholarly journals Borrelia burgdorferi Resistance to a Major Skin Antimicrobial Peptide Is Independent of Outer Surface Lipoprotein Content

2009 ◽  
Vol 53 (10) ◽  
pp. 4490-4494 ◽  
Author(s):  
Amit Sarkar ◽  
Kit Tilly ◽  
Philip Stewart ◽  
Aaron Bestor ◽  
James M. Battisti ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Antimicrobial Peptide ◽  
Immune Evasion ◽  
Essential Role ◽  
Potential Role ◽  
Innate Immune ◽  
Initial Stage ◽  
Mammalian Infection ◽  
Innate Immune Evasion

ABSTRACT We hypothesize a potential role for Borrelia burgdorferi OspC in innate immune evasion at the initial stage of mammalian infection. We demonstrate that B. burgdorferi is resistant to high levels (>200 μg/ml) of cathelicidin and that this antimicrobial peptide exhibits limited binding to the spirochetal outer membrane, irrespective of OspC or other abundant surface lipoproteins. We conclude that the essential role of OspC is unrelated to resistance to this component of innate immunity.

Enhancing of anthracnose disease resistance indicates a potential role of antimicrobial peptide genes in cassava

Genetica ◽  
2020 ◽  
Vol 148 (3-4) ◽  
pp. 135-148
Author(s):  
Pattaraporn Hormhuan ◽  
Unchera Viboonjun ◽  
Punchapat Sojikul ◽  
Jarunya Narangajavana
Keyword(s):  
Disease Resistance ◽  
Antimicrobial Peptide ◽  
Potential Role ◽  
Anthracnose Disease

scholarly journals High Prevalence and Diversity of Cephalosporin-Resistant Enterobacteriaceae Including Extraintestinal Pathogenic E. coli CC648 Lineage in Rural and Urban Dogs in Northwest Spain

Antibiotics ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 468 ◽  
Author(s):  
Fátima Abreu-Salinas ◽  
Dafne Díaz-Jiménez ◽  
Isidro García-Meniño ◽  
Pilar Lumbreras ◽  
Ana María López-Beceiro ◽  
...  
Keyword(s):  
High Risk ◽  
Antimicrobial Resistance ◽  
One Health ◽  
Potential Role ◽  
Multidrug Resistant ◽  
E Coli ◽  
Rural And Urban ◽  
High Prevalence ◽  
Healthy Dogs

The aim of this work was to assess the prevalence of extended spectrum-β-lactamase (ESBL)- and carbapenemase-producing Enterobacteriaceae in fecal samples recovered from rural and urban healthy dogs in Northwest Spain (Galicia) to identify potential high-risk clones and to molecularly characterize positive isolates regarding the genes coding for ESBL/pAmpC resistance and virulence. Thirty-five (19.6%) out of 179 dogs were positive for cephalosporin-resistant Enterobacteriaceae, including Escherichiacoli and Klebsiella pneumoniae (39 and three isolates, respectively). All the isolates were multidrug resistant, with high rates of resistance to different drugs, including ciprofloxacin (71.4%). A wide diversity of ESBL/pAmpC enzymes, as well as E. coli phylogroups (A, B1, C, D, E, F and clade I) were found. The eight isolates (20.5%) found to conform to the ExPEC status, belonged to clones O1:H45-clade I-ST770 (CH11-552), O18:H11-A-ST93-CC168 (CH11-neg), O23:H16-B1-ST453-CC86 (CH6-31), and O83:H42-F-ST1485-CC648 (CH231-58), with the latter also complying the uropathogenic (UPEC) status. The three K. pneumoniae recovered produced CTX-M-15 and belonged to the ST307, a clone previously reported in human clinical isolates. Our study highlights the potential role of both rural and urban dogs as a reservoir of high-risk Enterobacteriaceae clones, such as the CC648 of E. coli and antimicrobial resistance traits. Within a One-Health approach, their surveillance should be a priority in the fight against antimicrobial resistance.

scholarly journals Potential role of α-synuclein in neurodegeneration: studies in a rat animal model

2012 ◽  
Vol 122 (4) ◽  
pp. 812-822 ◽  
Author(s):  
George Stoica ◽  
Gina Lungu ◽  
Nicole L. Bjorklund ◽  
Giulio Taglialatela ◽  
Xing Zhang ◽  
...  
Keyword(s):  
Animal Model ◽  
Potential Role ◽  
Rat Animal Model

Potential role of non-antibiotics (helper compounds) in the treatment of multidrug-resistant Gram-negative infections: mechanisms for their direct and indirect activities

2008 ◽  
Vol 31 (3) ◽  
pp. 198-208 ◽  
Author(s):  
Marta Martins ◽  
Sujata G. Dastidar ◽  
Seamus Fanning ◽  
Jette E. Kristiansen ◽  
Joseph Molnar ◽  
...  
Keyword(s):  
Potential Role ◽  
Multidrug Resistant ◽  
Gram Negative

Potential role of Indian long pepper (Piper longum L.) volatiles against free radicals and multidrug resistant isolates

2021 ◽  
pp. 1-5
Author(s):  
Manaswini Dash ◽  
Subhashree Singh ◽  
Bhaskar Chandra Sahoo ◽  
Suprava Sahoo ◽  
Rajesh Kumar Sahoo ◽  
...  
Keyword(s):  
Free Radicals ◽  
Potential Role ◽  
Multidrug Resistant ◽  
Piper Longum
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