scholarly journals Gender-Specific Independent and Combined Effects of the Progesterone and 17-Hydroxyprogesterone on Metabolic Syndrome: From the Henan Rural Cohort Study

2021 ◽  
Vol Volume 14 ◽  
pp. 4297-4306
Author(s):  
Mian Wang ◽  
Luting Nie ◽  
Dandan Wei ◽  
Pengling Liu ◽  
Li Zhang ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Combined Effects ◽  
17 Hydroxyprogesterone ◽  
Gender Specific

scholarly journals Combined Effects of Smoking and Alcohol on Metabolic Syndrome: The LifeLines Cohort Study

PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e96406 ◽  
Author(s):  
Sandra N. Slagter ◽  
Jana V. van Vliet-Ostaptchouk ◽  
Judith M. Vonk ◽  
H. Marieke Boezen ◽  
Robin P. F. Dullaart ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Combined Effects

scholarly journals Combined Effects of Sleep Disordered Breathing and Metabolic Syndrome on Endothelial Function: The Wisconsin Sleep Cohort Study

SLEEP ◽  
2014 ◽  
Vol 37 (10) ◽  
pp. 1707-1713 ◽  
Author(s):  
Claudia E. Korcarz ◽  
James H. Stein ◽  
Paul E. Peppard ◽  
Terry B. Young ◽  
Jodi H. Barnet ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Endothelial Function ◽  
Sleep Disordered Breathing ◽  
Combined Effects ◽  
Disordered Breathing

Thyroid function and metabolic syndrome: results from the population-based LifeLines Cohort study

2017 ◽  
Author(s):  
Bruce Wolffenbuttel ◽  
Hanneke Wouters ◽  
Sandra Slagter ◽  
Waateringe Robert van ◽  
Vliet-Ostaptchouk Jana van ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Thyroid Function ◽  
Population Based

1603-P: Changes in Age- and Gender-Specific All-Cause Mortality Rates and Ratios in People with T2DM in Hungary between 2001-2016: A Nationwide Cohort Study

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1603-P
Author(s):  
GYORGY JERMENDY ◽  
ZOLTAN KISS ◽  
GYÖRGY ROKSZIN ◽  
IBOLYA FÁBIÁN ◽  
ISTVAN WITTMANN ◽  
...  
Keyword(s):  
Cohort Study ◽  
Mortality Rates ◽  
Age And Gender ◽  
All Cause Mortality ◽  
And Gender ◽  
Gender Specific

2453-PUB: Changes in Metabolic Syndrome and Diabetes Risk: A Nationwide Longitudinal Cohort Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2453-PUB
Author(s):  
MIN-KYUNG LEE ◽  
HYUK-SANG KWON ◽  
KI-HO SONG ◽  
JAE HYUK LEE
Keyword(s):  
Metabolic Syndrome ◽  
Cohort Study ◽  
Diabetes Risk ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort

scholarly journals Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kosuke Honda ◽  
Satoru Kuriyama ◽  
Kimiyoshi Ichida ◽  
Tomoko Nakano ◽  
Naoki Sugano ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Renal Function ◽  
Uric Acid ◽  
Cohort Study ◽  
Serum Uric Acid Level ◽  
Human Growth ◽  
Longitudinal Cohort Study ◽  
Longitudinal Cohort

Abstract Background Insulin-like growth factor-1 (IGF-1) acts on glucose and protein metabolism and human growth and also influences blood pressure and renal function. This study investigated whether the single-nucleotide polymorphism of IGF-1, rs35767, plays a role in metabolic syndrome indicators, including blood pressure, glucose metabolism, uric acid levels, and renal function. Methods In this retrospective longitudinal cohort study, blood samples from 1506 Japanese individuals were collected and used for genotyping for variant rs35767: T > C in the IGF-1 upstream promoter. Data were analyzed to identify associations between IGF-1 genotypes and patient biochemical parameters, including the components of metabolic syndrome and the long-term change in renal function. Results The cohort rs35767 genotypes included 650 CC carriers (43.2%), 687 TC carriers (45.6%), and 169 TT carriers (11.2%). Multiple regression analysis revealed no association between IGF-1 genotype and blood pressure, glycated hemoglobin level, and serum uric acid level. However, in females, blood pressure was negatively correlated with the TT genotype. Longitudinal observation revealed that the decline in eGFR over 10 years was greater in TT (− 18.51 ± 1.04 mL/min/1.73m2) than in CC carriers (− 16.38 ± 0.52 mL/min/1.73m2; P < 0.05). Conclusion The present study suggests that renal function declines faster in individuals with the TT genotype at the IGF-1 rs35767 locus than in those with the CC genotype, suggesting that the TT genotype is associated with the long-term chronological decline in renal function.

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