scholarly journals Progressive Loss of Corneal Nerve Fibers and Sensitivity in Rats Modeling Obesity and Type 2 Diabetes Is Reversible with Omega-3 Fatty Acid Intervention: Supporting Cornea Analyses as a Marker for Peripheral Neuropathy and Treatment

2020 ◽  
Vol Volume 13 ◽  
pp. 1367-1384
Author(s):  
Lawrence Coppey ◽  
Eric Davidson ◽  
Hanna Shevalye ◽  
Alexander Obrosov ◽  
Michael Torres ◽  
...  
2019 ◽  
Vol 74 ◽  
pp. 108249 ◽  
Author(s):  
Yu Zhang ◽  
Pan Zhuang ◽  
Lei Mao ◽  
Xiaoqian Chen ◽  
Jun Wang ◽  
...  

JAMA ◽  
2019 ◽  
Vol 322 (19) ◽  
pp. 1899 ◽  
Author(s):  
Ian H. de Boer ◽  
Leila R. Zelnick ◽  
John Ruzinski ◽  
Georgina Friedenberg ◽  
Julie Duszlak ◽  
...  

2012 ◽  
Vol 6 (1) ◽  
pp. 122-125 ◽  
Author(s):  
Vasilios G Athyros ◽  
Dimitri P Mikhailidis

This is a case report that describes a 67-year-old woman with mixed hyperlipidemia and diabetic nephropathy. She was initially prescribed a combination of simvastatin plus gemfibrozil by her general practitioner (GP). When referred to our cardiovascular unit, we further diagnosed the patient to have mixed hyperlipidemia and rhabdomyolysis. Because of concerns with her chronic kidney disease (CKD), we temporarily stopped all her drug treatments and started insulin treatment for her type 2 diabetes (T2D). A month later when her T2D was stabilised, we prescribed atorvastatin and an omega-3 fatty acid ethyl ester supplement to treat her hypertriglyceridemia. Within two months her blood lipids were within the recommended range. In patients with stage 3–5 CKD, it is not advisable to prescribe the fibrate gemfibrozil, particularly in combination with a statin that is metabolised predominantly in the kidneys. To minimise adverse events without compromise on efficacy, we used a combination of omega-3 fatty acid ethyl esters, which are not metabolised in the kidneys, with a statin that is minimally metabolised in the kidneys for the treatment of her hyperlipidemia.


2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Joan A Vaccaro ◽  
Joel C Exebio ◽  
Sahar Ajabshir ◽  
Gustavo G Zarini ◽  
Fatma G Huffman

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