scholarly journals Adverse effects of isoniazid preventative therapy for latent tuberculosis infection: a prospective cohort study

2014 ◽  
pp. 145 ◽  
Author(s):  
Justin Denholm ◽  
Emma McBryde ◽  
Damon Eisen ◽  
Caroline Chen ◽  
Jocelyn Penington ◽  
...  
Keyword(s):  
Cohort Study ◽  
Adverse Effects ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Tuberculosis Infection ◽  
Preventative Therapy ◽  
Isoniazid Preventative Therapy

scholarly journals Treatment completion for latent tuberculosis infection in Norway: a prospective cohort study

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Yvette Louise Schein ◽  
Tesfaye Madebo ◽  
Hilde Elise Andersen ◽  
Trude Margrete Arnesen ◽  
Anne Ma Dyrhol-Riise ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Treatment Completion ◽  
Tuberculosis Infection

scholarly journals Mania induced by isoniazid preventive therapy during steroid treatment for rheumatoid arthritis and organising pneumonia

2019 ◽  
Vol 12 (11) ◽  
pp. e231919 ◽  
Author(s):  
Hiroyuki Nagano ◽  
Tomoaki Miura ◽  
Takeshi Ueda
Keyword(s):  
Rheumatoid Arthritis ◽  
Infectious Disease ◽  
Adverse Effects ◽  
Latent Tuberculosis Infection ◽  
Latent Tuberculosis ◽  
Preventive Therapy ◽  
Steroid Treatment ◽  
Preventative Therapy ◽  
Isoniazid Preventative Therapy ◽  
Long Time

Isoniazid preventative therapy is widely used for latent tuberculosis infection. Isoniazid is highly effective but has many adverse effects, including neuropsychiatric. We describe the case of an 80-year-old woman with mania. She had received isoniazid preventative therapy during steroid treatment for rheumatoid arthritis and organising pneumonia for the previous 5 months. Her mania resolved after discontinuation of isoniazid. Adverse effects of isoniazid should be considered even if a long time has elapsed since the start of administration. Physicians other than infectious disease and respiratory specialists also must be aware of the adverse effects of isoniazid preventative therapy.

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