scholarly journals Medication Errors Among Hospitalized Adults in Medical Wards of Nekemte Specialized Hospital, West Ethiopia: A Prospective Observational Study

2021 ◽  
Vol Volume 13 ◽  
pp. 221-228
Author(s):  
Mohammed Gebre ◽  
Nigatu Addisu ◽  
Ayantu Getahun ◽  
Jenber Workye ◽  
Busha Gamachu ◽  
...  

This case focuses on medication errors and adverse drug events occurring during the perioperative period by asking the question: What are the rates, types, severity, and preventability of medication errors (MEs) and adverse drug events (ADEs) in the perioperative setting during anesthesia care? This prospective observational study reported that approximately 1 in 20 perioperative medication administrations, and every second operation, resulted in an ME and/or an ADE. These rates are markedly higher than those reported by prior retrospective surveys. Process- and technology-based solutions may address the root causes of MEs to reduce their incidence.


2019 ◽  
Vol 2019 ◽  
pp. 1-8
Author(s):  
Alemseged Beyene Berha ◽  
Gizat Molla Kassie

Objective. The aim of the present study was to explore the current practice and its barriers to an early antimicrobial conversion from intravenous (IV) to oral (PO) therapy among hospitalized patients.Method. Hospital based prospective observational study was conducted to assess the practice of an early antimicrobial IV to PO conversion and its barriers using medical chart and case-specific physicians’ interviews, respectively, from February to September, 2014. Patient charts and medication records were reviewed for appropriateness of IV to PO conversion program every 24hrs using a pretested data collection abstraction format. Independent samplest-test was used to compare the duration of therapy and time to clinical stability between converted and nonconverted patients. Two-tailed P values of < 0.05 were regarded as statistically significant.Results. One hundred forty-two patients were included in the study, of whom two-thirds (67.6%) of the patients were eligible for IV to PO antimicrobial conversion. However, only 20.9% of patients’ timely conversion was made. A shorter duration of IV therapy was recorded for converted (2.80±1.87) versus nonconverted patients (8.50±6.32), (P=0.009). The most important barriers of not converting IV to PO in clinically stable patients were presence of comorbidity; clinicians perceived that the patient should always complete IV course of antimicrobials as a standard practice.Conclusion. Conversion from IV to PO antimicrobials was found to be unnecessarily delayed in a significant proportion of patients hospitalized with moderate to severe infection due to a range of different barriers. Addressing these issues has the potential to reduce inappropriate antimicrobial use and resistance.


BMJ ◽  
2004 ◽  
Vol 329 (7478) ◽  
pp. 1321 ◽  
Author(s):  
Eran Kozer ◽  
Winnie Seto ◽  
Zulfikaral Verjee ◽  
Chris Parshuram ◽  
Sohail Khattak ◽  
...  

2021 ◽  
Vol 9 ◽  
pp. 205031212198962
Author(s):  
Firomsa Bekele ◽  
Ginenus Fekadu ◽  
Kumera Bekele ◽  
Dinka Dugassa ◽  
Jiregna Sori

Introduction: Drug-related problems can affect the treatment outcomes of hospitalized patients and outpatients that lead to morbidity and mortality. Despite this, there were scanty of studies among patients with infectious diseases in Ethiopia. As the result, this study was tried to assess the magnitude and determinants of drug therapy problems among infectious disease patients admitted to the medical wards of Wollega University Referral Hospital. Methods: A prospective observational study was conducted from May to August 2019. The prevalence and types of drug- related therapy problems were studied using the Pharmaceutical Care Network Europe Foundation classification system, and adverse drug reaction was assessed by using the Naranjo algorithm. Multivariable logistic regression analysis was used to determine the predictors of drug-related problems, and a significant association was declared if p-value < 0.05. Result: Of the 172 study participants, 106 (61.6%) were males, and the patient’s mean age was 39.1 ± 14.31 years. Over the study period, 123 (71.51%) patients had drug-related problems. Need for additional drug therapy was the widely occurred drug-related problem that accounts for 107 (22.77%), and the most common drug-associated with the drug therapy problem was ceftriaxone (77 (44.77%)). This inappropriate use of ceftriaxone might be due to the preference of physicians to prescribe this broad spectrum antibiotic in which it was prescribed for the majority of the infectious disease etiology. Polypharmacy (adjusted odds ratio (AOR) = 2.505, 95% confidence interval (CI): 1.863–11.131), length of hospital stay ⩾ 7 days (AOR = 4.396, 95% CI: 1.964–7.310), and presence of co-morbidity (AOR = 2.107, 95% CI: 1.185–4.158, p = 0.016) were determinants of drug-related problems. Conclusion: The magnitude of drug-related problems was found to be high. Hence, the clinical pharmacy service should be established to tackle inappropriate indications, ineffective drug therapy, and adverse drug events in the study area.


2019 ◽  
Vol 9 (6-s) ◽  
pp. 103-106
Author(s):  
Peddolla Sushma Reddy ◽  
Vidya Biju ◽  
Inuganti Bhavana

Background: Medication error is defined as any avertable event that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient and consumer. Medication errors may occur at any stage of the medication use process including ordering, transcription, dispensing, administering and monitoring.  Objective: The objective of the study is to assess the medication errors in a tertiary care hospital and to categorize them based on their nature and type. Methodology: A prospective observational study was conducted over a period of 3 months in a tertiary care teaching hospital. This study was carried out among 240 inpatients, admitted in General Medicine department of the hospital, who were selected randomly. During the study, inpatients case records were reviewed, which includes patient’s case history, diagnosis, medication order sheets, progress chart, laboratory investigations. The data collected were analyzed for identifying medication errors such as prescribing errors and administration errors. Each reported medication error was assessed using the National Coordinating Council for Medication Error Reporting and Prevention (NCCMERP) proposed index for categorizing medication errors. Results: A total number of 240 inpatients were enrolled in the study, out of which 82 patients have developed medication errors. The overall percentage of observed medication error was 34.16%. In our study medication errors were found more in males (70.7%) than in the females (29.3%). Prescribing errors (62.19%) were the most frequently occurring type of error, which was followed by administration errors (37.8%). In our study, we found that medication errors were more with antibiotics (37) followed by NSAIDs (19). 96 prescriptions were found having drug interactions. Conclusion: This study concludes that the overall incidence of medication error was found to be 34.16%. Most of the medication errors are clinically significant and it can prevent by working together in a health care team.  


2019 ◽  
Vol 1 (8) ◽  
pp. e403-e412 ◽  
Author(s):  
Sarah P Slight ◽  
Clare L Tolley ◽  
David W Bates ◽  
Rachel Fraser ◽  
Theophile Bigirumurame ◽  
...  

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