scholarly journals Effects of Eperisone Hydrochloride and Non-Steroid Anti-Inflammatory Drugs (NSAIDs) for Acute Non-Specific Back Pain with Muscle Spasm: A Prospective, Open-Label Study

2020 ◽  
Vol Volume 12 ◽  
pp. 221-228
Author(s):  
Rizaldy Taslim Pinzon ◽  
Vincent Ongko Wijaya ◽  
Dessy Paramitha ◽  
Raymondus Rangga Bagaskara
Keyword(s):  
Back Pain ◽  
Muscle Spasm ◽  
Open Label ◽  
Open Label Study ◽  
Label Study ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Fenbufen, a New Non-Steroidal Anti-Inflammatory Agent in Rheumatoid Arthritis, its Efficacy and Toxicity

1980 ◽  
Vol 8 (5) ◽  
pp. 333-338 ◽  
Author(s):  
Alfred Becker ◽  
Rex T Hoffmeister
Keyword(s):  
Rheumatoid Arthritis ◽  
Side Effects ◽  
Half Life ◽  
Butanoic Acid ◽  
Open Label ◽  
Open Label Study ◽  
Label Study ◽  
Inflammatory Agent ◽  
Anti Inflammatory ◽  
Mild Toxicity

Fenbufen, a new butanoic acid derivative with anti-inflammatory properties, was evaluated in an open-label study. It was found that fenbufen was an effective anti-inflammatory agent with tolerable and acceptable potential side-effects. Its advantages appeared to be its long clinical half-life and relatively mild toxicity and/or allergic response.

scholarly journals Evaluation of Recovery Rate in COVID-19 Patients Treated with Steroidal Drugs

2021 ◽  
pp. 249-255
Author(s):  
V. V. Rajesham ◽  
B. Rekha ◽  
Gayathri Kothawar ◽  
N. Lavanya ◽  
B. Pallavi ◽  
...  
Keyword(s):  
Inflammatory Responses ◽  
Open Label ◽  
Open Label Study ◽  
Beneficial Effects ◽  
Time Period ◽  
The Family ◽  
Recovery Percentage ◽  
Inflammatory Drugs ◽  
Males And Females ◽  
Anti Inflammatory

Introduction: Coronavirus belongs to the family coronaviridae that majorly affects the respiratory system this group of virus outbreak previously as SARS and MERS in various countries and recently as COVID-19. COVID-19 has symptoms like fever, dry cough, breathing problems, loss of smell and taste, body aches. COVID-19 has spread to 210 countries and infected 272.51 million people worldwide, reached over 5.34 million deaths. Treatment includes antivirals, antibiotics, Non Steroidal Anti-Inflammatory Drugs, corticosteroids. Methodology: It is a hospital-based retro-prospective study was conducted for 6 months in the Inpatient department. 100 patients were taken who met the inclusion criteria. Data collected and evaluated, analyzed by open label study. Results and Discussion: severe COVID-19 can develop systemic inflammatory responses that can lead to lung injury and multisystem organ dysfunction. It has been proposed that the potent anti-inflammatory effects of corticosteroids might prevent or mitigate these deleterious effects. Both beneficial and deleterious clinical outcomes have been reported with the use of corticosteroids in patients with other pulmonary infections From study, The Recovery% using steroids in the time period of 0-10 and 11-20 days was found to be 34 and 27% respectively. The Recovery percentage using steroids in the time period of 0-10 and 11-20 days was found to be 18 and 8% respectively. Dexamethasone was most commonly used in males and females, 77.08 and 84% respectively. Conclusion: Considering beneficial effects of corticosteroids in COVID -19, prescribing steroids is safe by dose tapering continued up to 10days or hospital discharge

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