scholarly journals Clinicopathological significance and a potential drug target of RARβ in non-small-cell lung carcinoma: a meta-analysis and a systematic review

2016 ◽  
pp. 1345 ◽  
Author(s):  
Yi Han ◽  
Xiaoyun Song ◽  
Kang Shi ◽  
Shi-Jie Zhou ◽  
Da-Ping Yu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Drug Target ◽  
Small Cell Lung Carcinoma ◽  
Meta Analysis ◽  
Small Cell ◽  
Potential Drug Target ◽  
Potential Drug ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma ◽  
Clinicopathological Significance

scholarly journals Prognostic Value of Survivin in Patients with Non-Small Cell Lung Carcinoma: A Systematic Review with Meta-Analysis

PLoS ONE ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. e34100 ◽  
Author(s):  
Lou Qian Zhang ◽  
Jun Wang ◽  
Feng Jiang ◽  
Lin Xu ◽  
Fu Yin Liu ◽  
...  
Keyword(s):  
Systematic Review ◽  
Lung Carcinoma ◽  
Prognostic Value ◽  
Small Cell Lung Carcinoma ◽  
Meta Analysis ◽  
Small Cell ◽  
Small Cell Lung ◽  
Cell Lung Carcinoma

scholarly journals MALAT-1 Expression Correlates with Prognosis in Non-Small-Cell Lung Carcinoma: A Systematic Review and Meta-analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Ran Ran ◽  
Jian-wei Jin ◽  
Wei-ping Zhang
Keyword(s):  
Systematic Review ◽  
Lung Carcinoma ◽  
Noncoding Rna ◽  
Small Cell Lung Carcinoma ◽  
Meta Analysis ◽  
Small Cell ◽  
Cochrane Library ◽  
Small Cell Lung ◽  
China National Knowledge Infrastructure ◽  
Cell Lung Carcinoma

Background. Non-small-cell lung carcinoma (abbreviated as NSCLC) progresses rapidly and lacks appropriate biological markers. Recent studies have shown that long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT-1) has potential application value for clinically diagnosing lung carcinoma. Thus, this study conducted a systematic review and meta-analysis for assessing if MALAT-1 has a relationship to NSCLC outcome. Methods. This study conducted the search of China National Knowledge Infrastructure, China Science and Technology Journal, SinoMed, EMBASE, Cochrane library, Web of Science, Wanfang database, and PubMed from inception to September, 1, 2021. The published article about MALAT-l expression for NSCLC patients was analyzed. We used combined hazard rates under the confidence interval of 95% for examining the relationship of MALAT-l and NSCLC.Results. In this meta-analysis, we found that 10 studies were included, and MALAT-1 expressions were distinctly related to an unfavorable overall survival (HR: 2.34 (1.65, 3.33); I2 = 76%). Considering the merger’s clinical heterogeneity, for meta-analysis, we used the random-effects method. Conclusion. Overexpression of MALAT-1 showed correlations to the less effective outcome of NSCLC. MALAT-1 might be a new NSCLC prognosis marker.

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