scholarly journals A study of refractory cases of persistent epithelial defects associated with dry eye syndrome and recurrent corneal erosions successfully treated with cyclosporine A 0.05% eye drops

2019 ◽  
Vol Volume 13 ◽  
pp. 2001-2008 ◽  
Author(s):  
Pietro Emanuele Napoli ◽  
Mirco Braghiroli ◽  
Claudio Iovino ◽  
Giuseppe Demarinis ◽  
Maurizio Fossarello
Keyword(s):  
Dry Eye ◽  
Cyclosporine A ◽  
Dry Eye Syndrome ◽  
Eye Drops ◽  
Persistent Epithelial Defects

A Comparison of Vitamin A and Cyclosporine A 0.05% Eye Drops for Treatment of Dry Eye Syndrome

2009 ◽  
Vol 147 (2) ◽  
pp. 206-213.e3 ◽  
Author(s):  
Eun Chul Kim ◽  
Jun-Sub Choi ◽  
Choun-Ki Joo
Keyword(s):  
Vitamin A ◽  
Dry Eye ◽  
Cyclosporine A ◽  
Dry Eye Syndrome ◽  
Eye Drops

scholarly journals A Meta-Analysis of the Efficacy of Hyaluronic Acid Eye Drops for the Treatment of Dry Eye Syndrome

2021 ◽  
Vol 18 (5) ◽  
pp. 2383
Author(s):  
Yun-Jung Yang ◽  
Won-Young Lee ◽  
Young-jin Kim ◽  
Yeon-pyo Hong
Keyword(s):  
Hyaluronic Acid ◽  
Confidence Interval ◽  
Dry Eye ◽  
Test Scores ◽  
Meta Analysis ◽  
Mean Difference ◽  
Dry Eye Syndrome ◽  
Eye Drops ◽  
Cochrane Central Register ◽  
Standard Mean Difference

Hyaluronic acid (HA) is commonly used for treating dry eye syndrome (DES). This meta-analysis was performed to compare the efficacies of HA- and non-HA-based eye drops, including saline and conventional artificial tears (ATs), for the treatment of dry eye disease. Eight databases (PubMed, EMBASE, Cochrane Central Register of Controlled Trials, DBpia, KoreaMed, KMBASE, RISS, KISS) were searched for studies comparing the efficacies of HA- and non-HA-based ATs in patients with DES published up to September 2020. Two independent reviewers assessed the quality and extracted the relevant data. The mean differences of Schirmer’s (SH) test scores, tear breakup times (TBUT), corneal fluorescein staining scores (Oxford scale, 0–4), and ocular surface disease indexes were calculated. The standard mean difference and 95% confidence interval were calculated using a random effect model. Nineteen studies, including 2078 cases, were included. HA eye drops significantly improved tear production compared with non-HA-based eye drops (standard mean difference (SMD) 0.18; 95% confidence interval (CI) 0.03, 0.33). In a subgroup analysis, the SH test scores and TBUT values after using HA significantly increased compared to those measured after using saline (SMD 0.27; 95% CI 0.05, 0.49 and SMD 0.28; 95% CI 0.03, 0.52, respectively). Based on these results, HA eye drops may be superior to non-HA eye drops including normal saline and ATs. Further research is needed to assess the efficacies stratified by age, treatment duration, the severity of dry eye, and optimal dosages.

«Dry eye» syndrome and primary glaucoma: possibilities of treatment

Reflection ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 42-44
Author(s):  
L.I. Solovyova ◽  
◽  
T.V. Gavrilova ◽  
F.G. Mugumova ◽  
◽  
...  
Keyword(s):  
Dry Eye ◽  
Open Angle Glaucoma ◽  
Tear Film ◽  
Dry Eye Syndrome ◽  
Rupture Time ◽  
Eye Drops ◽  
Film Rupture ◽  
Good Tolerability ◽  
Primary Glaucoma ◽  
The Stability

The article presents the results of Ocuhyl C using in the treatment of «dry eye syndrome» (DES) in 47 eyes of 26 patients with different stages of compensated primary open-angle glaucoma. Experience of instillation of hypotensive eye drops with preservatives was from 1 year to 35 years. Assessment of subjective signs of DES was performed by questioning. Functional tests were performed (for the stability of the precorneal tear film –Norn test, for the level of total tear production –Shirmer test). Examinations were carried out at the first examination before prescribing the drug, then after 4 and 8 weeks of its use. All the patients noted good tolerability of the drug, no side effects. Indicators characterizing the feeling of a foreign body, dryness and redness of the eyes have significantly decreased. Precorneal tear film rupture time has significantly increased. Ocuhyl C can be recommended for clinical use. Key words: primary glaucoma; “dry eye” syndrome; tear forming; tear film rupture time; Ocuhyl C.

Using 20% honey solution eye drops in patients with dry eye syndrome

2007 ◽  
Vol 46 (4) ◽  
pp. 232-235 ◽  
Author(s):  
Jurate Jankauskiene ◽  
Dalia Jarushaitiene ◽  
Violeta Cheksteryte ◽  
Jurgis Rachys
Keyword(s):  
Dry Eye ◽  
Dry Eye Syndrome ◽  
Eye Drops ◽  
Honey Solution

scholarly journals Analysis of treatment results in dry eye syndrome patients after phacoemulsification by preservative-free 0.3% sodium hyaluronate eye drops

2017 ◽  
Vol 10 (2) ◽  
pp. 73-77
Author(s):  
Yury I Pirogov ◽  
Galina M Butina ◽  
Aleksandr A Oksentjuk ◽  
Ekaterina S Khromova
Keyword(s):  
Dry Eye ◽  
Sodium Hyaluronate ◽  
Dry Eye Syndrome ◽  
Surgical Trauma ◽  
Eye Drops ◽  
Mean Values ◽  
Tear Secretion ◽  
Mild Degree ◽  
Patient Symptom ◽  
Preservative Free

Postsurgical dry eye syndrome is found in a substantial proportion of patients after phacoemulsification. Its onset could be explained by surgical trauma and by use of preservative-containing eye drops. In some patients, it causes substantial discomfort that continues unabated after 3-4 weeks after surgery. Purpose. To investigate the results of 0.3% sodium hyaluronate instillation therapy used to treat dry eye syndrome after phacoemulsification. Materials and methods. Basal tear secretion (Schirmer II test) and tear breakup time (TBUT) test were investigated in 33 patients with symptoms characteristic of dry eye syndrome in 1 month after phacoemulsification. These patients received 0.3% preservative-free sodium hyaluronate instillations for 30 days, whereupon Schirmer II and TBUT tests were repeated. Symptom dynamics was estimated according to the OSDI questionnaire scale. Results. Mean values of basal tear secretion and TBUT tests were slightly below normal ones. In one month of treatment, the TBUT index associated with “Gilan Ultra Comfort” use became somewhat better: mean TBUT value appeared to be 9.8 ± 2.5 sec. OSDI questionnaire patient symptom score evaluation also revealed in patients a mild degree of xerosis severity. Mean score before treatment was 19.6 ± 10.0. Positive disease dynamics after “Gilan Ultra Comfort” use is confirmed by a significant decrease of OSDI score index up to 12.3 ± 6.3.

scholarly journals “DRY EYE” SYNDROME IN THE CHILDREN: CURRENT POSSIBILITIES FOR DIAGNOSTICS AND TREATMENT (THE GUIDELINES FOR PRACTITIONERS)

2017 ◽  
Vol 12 (2) ◽  
pp. 73-81
Author(s):  
Vladimir Vsevolodovich Brzheskiy
Keyword(s):  
Dry Eye ◽  
Specific Treatment ◽  
Diagnostic Value ◽  
Dry Eye Syndrome ◽  
Eye Drops ◽  
Congenital Diseases ◽  
Age Related ◽  
Ready Availability ◽  
Extensive Introduction ◽  
The One

Purpose. The «dry eye» syndrome in the children occurs much less frequently than in the adults, but it is often diagnosed in the contact lens wearers, the subjects presenting with the computer vision syndrome, and in the children with glaucoma (especially against the background of the instillations of the hypotensive eye drops with a preservative), chronic uveitis, diabetes mellitus, and certain congenital diseases of the eyelids and lacrimal glands. On the one hand, the pathology being considered is very similar in the children and adults in terms of etiology and pathogenesis, but on the other hand, it has a number of peculiar age-related features as regards the clinical course and the modes of treatment of this disease specific for either group of the patients. To begin with, the children very rarely complain about this condition and exhibit the relatively mild objective manifestations of the disorder (xerosis), with the exception of its extremely severe forms. Finally, the specific treatment of the children suffering from the «dry eye» syndrome with the majority of the medications currently available for the purpose is hampered by the age-related limitations whereas they are extensively and successfully used for the treatment of the same condition in the adults. Accordingly, the approaches to diagnostics of the «dry eye» syndrome in the children differ from those in the adults. Specifically, questioning of the children and their parents (to evaluate the complaints and the medical history) is of negligible diagnostic value whereas in the adults this approach provides the most valuable diagnostic information. In addition, it is very difficult to conduct a series of diagnostic tests in the young children due to their restless behavior during the examination. Conclusion. At the same time, there are currently the considerable opportunities for the diagnostics and treatment of the «dry eye» syndrome due to the ready availability of “artificial tear” preparations and stimulators of regeneration as well as the possibility of lacrimal duct obturation. It implies the necessity of the more extensive introduction of these modalities into the pediatric ophthalmological practiced.

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