scholarly journals The antiulcer effect of Cibotium barometz leaves in rats with experimentally induced acute gastric ulcer

2017 ◽  
Vol Volume11 ◽  
pp. 995-1009 ◽  
Author(s):  
Nahla Saeed AL-Wajeeh ◽  
Maryam Hajrezaei ◽  
Nawal Al-Henhena ◽  
Sareh Kamran ◽  
Elham Bagheri ◽  
...  
1997 ◽  
Vol 28 (3) ◽  
pp. 469-473 ◽  
Author(s):  
Zhen-Tao Wang ◽  
Qun Du ◽  
Guo-Jun Xu ◽  
Ru-Jun Wang ◽  
Ding-Zhong Fu ◽  
...  

2021 ◽  
Vol 13 (1) ◽  
pp. 308-315
Author(s):  
Vivek Srivastava ◽  
Santosh Kumar Verma ◽  
Neha Mathur ◽  
Kapil Kumar Goel

Albizzia procera belongs to family Fabaceae and has several phytoconstituents like flavonoids, terpenes, alkaloids, saponins etc. The plant is commonly used in traditional medicines. The objective of the present study was to assess the ameliorative effect of A. procera leaves extract against an experimentally induced gastric ulcer in albino rats. The antiulcer, antisecretory and cytoprotective properties of an ethanolic extract prepared from the leaves was evaluated. When given in a 200 mg/kg oral (per. os) dose, the extract produced 74% and 85% protection index in ethanol-induced ulcer model and pylorus ligation model, respectively.  Additionally, the extract also prohibited the formation of haemorrhage and edema, significantly lessened catalase activity (p<0.0001) and the lipid peroxidation level (p<0.0001) in the glandular tissue of Wistar albino rats. Furthermore, the extract also significantly diminished the total acidity(p<0.0001) of the gastric fluid by increasing its pH (p<0.0001). The occupancy of different phytoconstituents in the extract, such as flavonoids and tannins were identified that may be responsible for its gastro-protective activity. All these results provide a basis explaining the antiulcer ability of A. procera being useful in the management of gastric ulcers.


Heliyon ◽  
2020 ◽  
Vol 6 (8) ◽  
pp. e04761
Author(s):  
Alaa E. El-Sisi ◽  
Samia S. Sokar ◽  
Sally E. Abu-Risha ◽  
Doaa Y. Khira

1990 ◽  
Vol 183 (2) ◽  
pp. 310
Author(s):  
H.A. Shabayek ◽  
A.G. Radwan ◽  
A.A. Mostafa ◽  
Z.Y. Abdel-Kader ◽  
I. El-Naggar ◽  
...  

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