scholarly journals Measurement of tumor necrosis factor-α, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary disease

2008 ◽  
pp. 79
Author(s):  
Fanny Ko
Keyword(s):  
Exhaled Breath Condensate ◽  
Leukotriene B4 ◽  
Chronic Obstructive ◽  
Exhaled Breath ◽  
Necrosis Factor Alpha ◽  
Obstructive Pulmonary Disease ◽  
Acute Exacerbations ◽  
Factor Alpha ◽  
Breath Condensate ◽  
Necrosis Factor

scholarly journals Detection of Erythropoietin in Exhaled Breath Condensate of Nonhypoxic Subjects Using a Multiplex Bead Array

2006 ◽  
Vol 2006 ◽  
pp. 1-5 ◽  
Author(s):  
Christian Schumann ◽  
Kathy Triantafilou ◽  
Stefan Krueger ◽  
Vinzenz Hombach ◽  
Martha Triantafilou ◽  
...  
Keyword(s):  
Exhaled Breath Condensate ◽  
Sleep Apnoea ◽  
Chronic Obstructive ◽  
Exhaled Breath ◽  
Obstructive Pulmonary Disease ◽  
Obstructive Sleep ◽  
Breath Condensate ◽  
Necrosis Factor ◽  
Multiplex Bead

As a noninvasive method, exhaled breath condensate (EBC) has gained importance to improve monitoring of lung diseases and to detect biomarkers. The aim of the study was to investigate, whether erythropoietin (EPO) is detectable in EBC. EBC was collected from 22 consecutive patients as well as from healthy individuals. Using a multiplex fluorescent bead immunoassay, we detected EPO in EBC, as well as tumour necrosis factor-α(TNF-α) in 13 out of 22 patients simultaneously (EPO 0.21±0.03 in U/mL and TNF-α34.6±4.2 in pg/mL, mean±SEM). No significant differences for EPO levels or correlation between EPO and TNF-αwere found but TNF-αwas significantly higher in patients with chronic obstructive pulmonary disease (COPD) than in non-COPD (obstructive sleep apnoea, OSA, and lung healthy patients). This is the first report of detection of EPO in EBC. Due to the small study size more data is needed to clarify the role of EPO in EBC.

scholarly journals Exhaled breath condensate cytokine patterns in chronic obstructive pulmonary disease

2005 ◽  
Vol 99 (10) ◽  
pp. 1229-1240 ◽  
Author(s):  
Christian Gessner ◽  
Robert Scheibe ◽  
Michael Wötzel ◽  
Stefan Hammerschmidt ◽  
Hartmut Kuhn ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Exhaled Breath Condensate ◽  
Chronic Obstructive ◽  
Exhaled Breath ◽  
Obstructive Pulmonary Disease ◽  
Breath Condensate
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