scholarly journals Activity-related dyspnea in chronic obstructive pulmonary disease: physical and psychological consequences, unmet needs, and future directions

2019 ◽  
Vol Volume 14 ◽  
pp. 1127-1138 ◽  
Author(s):  
Nicola A Hanania ◽  
Denis E O'Donnell
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Unmet Needs ◽  
Chronic Obstructive ◽  
Psychological Consequences ◽  
Future Directions ◽  
Obstructive Pulmonary Disease

scholarly journals From Biomarkers to Novel Therapeutic Approaches in Chronic Obstructive Pulmonary Disease

Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1638
Author(s):  
Hsu-Hui Wang ◽  
Shih-Lung Cheng
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Unmet Needs ◽  
Chronic Obstructive ◽  
Biological Therapies ◽  
Therapeutic Approaches ◽  
Comprehensive Overview ◽  
Obstructive Pulmonary Disease ◽  
Complex Disorder ◽  
Treatment Support

Chronic obstructive pulmonary disease (COPD) is a heterogeneous and complex disorder. In this review, we provided a comprehensive overview of biomarkers involved in COPD, and potential novel biological therapies that may provide additional therapeutic options for COPD. The complex characteristics of COPD have made the recommendation of a generalized therapy challenging, suggesting that a tailored, personalized strategy may lead to better outcomes. Existing and unmet needs for COPD treatment support the continued development of biological therapies, including additional investigations into the potential clinical applications of this approach.

scholarly journals Understanding the role of the microbiome in chronic obstructive pulmonary disease: principles, challenges, and future directions

2017 ◽  
Vol 179 ◽  
pp. 71-83 ◽  
Author(s):  
Yvonne J. Huang ◽  
John R. Erb-Downward ◽  
Robert P. Dickson ◽  
Jeffrey L. Curtis ◽  
Gary B. Huffnagle ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Future Directions ◽  
Obstructive Pulmonary Disease

Exploring the interactional sphere of a systemic self-management intervention for chronic obstructive pulmonary disease (COPD)

2014 ◽  
Vol 3 (4) ◽  
pp. 291-304
Author(s):  
Ingeborg Farver-Vestergaard ◽  
Frances Early ◽  
Jonathan Fuld ◽  
Christina Gundgaard Pedersen
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Self Management ◽  
Chronic Obstructive ◽  
Management Support ◽  
Psychological Consequences ◽  
Obstructive Pulmonary Disease ◽  
Management Intervention ◽  
Management Interventions ◽  
Based Medicine

Patients with chronic obstructive pulmonary disease (COPD) face challenges in managing the physical and psychological consequences of the condition. Systemic self-management interventions based on the Wagner chronic care model seek to facilitate change in patient, healthcare professional (HCP) and healthcare system in order to support patients to self-manage their condition. Few studies have investigated the interactional sphere between patients and HCPs in the context of a systemic self-management intervention. The aim of the present study was to evaluate such an intervention and explore the discursive implications for self-management in COPD. Data were collected via interviews with patients and HCPs, observations of patient-provider interaction and document analysis of documents given to the patients to support self-management. An illustrative analytical model was developed on the basis of Willig’s discourse analysis guidelines. The findings suggested two different ways of talking about self-management – biomedical and patient-centred – that seemed to have implications for what speakers drawing on these discursive repertoires could say, do and experience in relation to self-management support and practice. Whilst the analytical method does not pass judgement on which discourse is ‘best’, results of this study show how the two identified discourses are oriented to different actions and positions, and highlight their relative strengths and limitations. The findings of the present study are relevant to the issue of how the ‘healthcare institution’, and evidence-based medicine as we know it, should be manifested – empirically and practically – in the future.

‘I’m fine’: exploring patient and carer assertions of status in advanced chronic obstructive pulmonary disease (COPD) and implications for primary care

2018 ◽  
Vol 68 (suppl 1) ◽  
pp. bjgp18X697145
Author(s):  
Carole Gardener ◽  
Caroline Moore ◽  
Morag Farquhar ◽  
Gail Ewing ◽  
Robbie Duschinsky
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Primary Care ◽  
Pulmonary Disease ◽  
Narrative Analysis ◽  
Service Use ◽  
Unmet Needs ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Mental Health Settings ◽  
Treatment Plans

BackgroundPatients can be reluctant to say that they need support, telling clinicians they are ‘fine’ despite having unmet needs. Research in mental health settings suggests patients who do this they are less likely to follow treatment plans, and their carers are at a risk of depression. To-date these findings have not been explored in patients with advancing physical health conditions, or their carers.AimTo explore the presence, role and impact of assertions of ‘I’m Fine’ in patients with advanced chronic obstructive pulmonary disease (COPD) and their carers.MethodCriteria based on Attachment Theory were used to identify ‘I’m Fine’ cases from the Living with Breathlessness Study (LwB) dataset of 235 patients and 115 carers. Quantitative analysis explored variables such as health service use between ‘I’m Fine’ and non ‘I’m Fine’ cases, whilst narrative analysis is being used to explore discourses within cases.Results21 patients and six carers asserted they were ‘fine’ despite unmet needs. Patients’ minimised disease impact and symptoms, avoided thinking about the future and used stoical language. Despite ‘I’m Fine’ cases being more likely to report no exacerbations and more likely to score less on the COPD Assessment Test (CAT), all wanted to see more of their GP. Carers focused on the needs of the patient whilst downplaying their own problems.ConclusionThe existence of a sub-group of patients with advanced COPD who assert that they are ‘fine’ may have implications for primary care. This will be explored in planned focus groups with clinicians.

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