scholarly journals The role of plasma N-terminal brain natriuretic pro-peptide in diagnosing elderly patients with acute exacerbation of COPD concurrent with left heart failure

2018 ◽  
Vol Volume 13 ◽  
pp. 2931-2940 ◽  
Author(s):  
Xuxue Guo ◽  
Hanxiang Nie ◽  
Qianhui Chen ◽  
Shuo Chen ◽  
Nishan Deng ◽  
...  
2004 ◽  
Vol 6 (2) ◽  
pp. 181-185 ◽  
Author(s):  
Laurent Fauchier ◽  
Dominique Babuty ◽  
Alexandre Melin ◽  
Pierre Bonnet ◽  
Pierre Cosnay ◽  
...  

CHEST Journal ◽  
2007 ◽  
Vol 132 (4) ◽  
pp. 480A ◽  
Author(s):  
Anant Mohan ◽  
Randeep Guleria ◽  
Charu Mohan ◽  
Surya P. Bhatt ◽  
Sneh Arora ◽  
...  

2017 ◽  
Vol 41 (S1) ◽  
pp. S142-S142
Author(s):  
I. Bonfitto ◽  
G. Moniello ◽  
M. Pascucci ◽  
A. Bellomo

IntroductionChronic obstructive pulmonary disease (COPD) represents the most common cause of chronic respiratory failure and it's associated with several comorbidities such as depression. Depression is about four times more frequent in elderly patients with COPD compared to peers who are not affected and its prevalence increases with the degree of disease severity.ObjectiveTo assess mood and perception of the quality of life in elderly patients hospitalized for acute exacerbation of COPD.MethodsThirty-five elderly patients hospitalized for reactivation of COPD were examined; they were subjected to spirometry test for the calculation of FEV1 and to COPD Assessment Test (CAT) and Hamilton Rating Scale for Depression (HAM-D) to evaluate impact of COPD on patients’ quality of life and depressive symptomatology, respectively. The number of COPD exacerbations in the last year prior to hospitalization and the number of recovery days required for the stabilization of patients were also recorded.ResultsThere were strongly significative correlations (P < 0.001), positive between HAM-D scores, CAT scores, number of exacerbation in the last year and hospital length of stay and negative between HAM-D scores and FEV1 values. Furthermore, females were more depressed, with lower FEV 1 (P = 0.043) and with a longer length of stay (P = 0.039) as compared to males.ConclusionsA greater severity of depressive symptoms is related to a greater severity of COPD exacerbations, disability associated with it and perceived by the patient, as well as a higher number of recovery days and annual acute exacerbations, particularly in female gender.


2020 ◽  
Vol 8 (10) ◽  
pp. 955-966
Author(s):  
Pankaj Kumar Singh ◽  
◽  
Mohit Bhatnagar ◽  
Sandeep Nimba Deore ◽  
Mandeep Joshi ◽  
...  

Aim and Objective: To investigate the role of Pneumonia Severity Index and CURB-65 score in patients with acute exacerbation of COPD with reference to Duration of hospital stay. Methods:In our study a total of 100 patients of COPD with acute exacerbation were included in the study from the tertiary care Centre, Kolkata for a period of 12 months from December 2015 to November 2016. Results: The relationship between Respiratory rate, Arterial pH, Urea and BUN levels, Blood glucose, Hematocrit level, pO2 as well as PSI and CURB-65 score in reference with duration of hospital was found to be significant. Our study revealed that PSI and CURB-65 score have good predictive capacity for in hospital deaths as well as duration of hospital stay. Conclusion: PSI and CURB -65 can predict the duration of hospital stay, with a good prognostic capacity. The role of PSI and CURB-65 in defining duration of hospital stay needs to be assessed by further studies on larger samples using Indian data for reference value. The present study is a stimulus to future research on role of PSI, CURB-65 as well as comorbidities in defining the outcome of acute exacerbations in COPD, one of the most dreaded respiratory diseases.


Diagnostics ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 554
Author(s):  
Silvia Terraneo ◽  
Rocco Francesco Rinaldo ◽  
Giuseppe Francesco Sferrazza Papa ◽  
Fulvia Ribolla ◽  
Carlo Gulotta ◽  
...  

Discriminating between cardiac and pulmonary dyspnea is essential for patients’ management. We investigated the feasibility and ability of forced oscillation techniques (FOT) in distinguishing between acute exacerbation of COPD (AECOPD), and acute decompensated heart failure (ADHF) in a clinical emergency setting. We enrolled 49 patients admitted to the emergency department (ED) for dyspnea and acute respiratory failure for AECOPD, or ADHF, and 11 healthy subjects. All patients were able to perform bedside FOT measurement. Patients with AECOPD showed a significantly higher inspiratory resistance at 5 Hz, Xrs5 (179% of predicted, interquartile range, IQR 94–224 vs. 100 IQR 67–149; p = 0.019), and a higher inspiratory reactance at 5 Hz (151%, IQR 74–231 vs. 57 IQR 49–99; p = 0.005) than patients with ADHF. Moreover, AECOPD showed higher heterogeneity of ventilation (respiratory system resistance difference at 5 and 19 Hz, Rrs5-19: 1.49 cmH2O/(L/s), IQR 1.03–2.16 vs. 0.44 IQR 0.22–0.76; p = 0.030), and a higher percentage of flow limited breaths compared to ADHF (10%, IQR 0–100 vs. 0 IQR 0–12; p = 0.030). FOT, which resulted in a suitable tool to be used in the ED setting, has the ability to identify distinct mechanical properties of the respiratory system in AECOPD and ADHF.


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